Hormone/growth factor interactions mediating epithelial/stromal communication in mammary gland development and carcinogenesis

Journal of Steroid Biochemistry and Molecular Biology

Volumn 80, Issue 2, 2002, Pages 213-230

  Imagawa, Walter ^a   Pedchenko, Vadim K ^a   Helber, Jennifer ^a   Zhang, Hongzheng ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

Fibroblast growth factors; Stroma; Tumor progression

Indexed keywords

ACTIVIN A; CYTOKINE; ENDOTHELIAL CELL GROWTH FACTOR; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR; FIBROBLAST GROWTH FACTOR; GROWTH FACTOR; INHIBIN B; ISOPROTEIN; KERATINOCYTE GROWTH FACTOR; LIPID; MYELOPID; NEU DIFFERENTIATION FACTOR; PARATHYROID HORMONE RELATED PROTEIN; PROGESTERONE; PROGESTERONE RECEPTOR; PROLACTIN; PROLACTIN RECEPTOR; SCATTER FACTOR; SEX HORMONE; SOMATOMEDIN B; SOMATOMEDIN C; TRANSFORMING GROWTH FACTOR BETA; WNT PROTEIN;

ARTICLE; BODY FAT; BREAST CANCER; BREAST CARCINOGENESIS; BREAST TUMOR; CANCER GROWTH; CELL COMMUNICATION; DRUG ACTIVITY; DRUG POTENTIATION; EPITHELIUM CELL; ESTROGEN ACTIVITY; HORMONAL REGULATION; HORMONE ACTION; HORMONE PROTEIN COMPLEX; HUMAN; INTERCELLULAR SPACE; MAMMARY GLAND; MICROENVIRONMENT; MITOGENESIS; NONHUMAN; ORGANOGENESIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; STROMA CELL;

ANIMALS; CELL COMMUNICATION; CELL TRANSFORMATION, NEOPLASTIC; EPITHELIAL CELLS; FEMALE; GROWTH SUBSTANCES; HORMONES; HUMANS; MAMMARY GLANDS, ANIMAL; MAMMARY NEOPLASMS, EXPERIMENTAL; STROMAL CELLS;

EID: 0036129964     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-0760(01)00188-1     Document Type: Article

References (185)

1. Role of mesenchymal-epithelial interactions in normal and abnormal development of the mammary gland and prostate
2. Paracrine mechanisms of mouse mammary ductal growth
3. The role of mammary stroma in modulating the proliferative response to ovarian hormones in the normal mammary gland
4. Organ specificity in mesenchymal induction demonstrated in the embryonic development of the mammary gland of the mouse
5. Mammary embryogenesis
6. Epithelium-mesenchyme interactions in the fetal mammary gland
7. Tissue interaction in androgen response of embryonic mammary rudiment of mouse: Identification of target tissue for testosterone
8. Mammary transplantation and its histogenesis in mice
9. New aspects of stroma-parenchyma relations in mammary gland differentiation
10. Capacity of mammary fat pads of adult C3H/HeMs mice to interact morphogenetically with fetal mammary epithelium
11. The effects of hormones on the vascular pattern of the mouse mammary gland
12. Changes in the fat cell morphology during lactation in the mouse
13. The mammary fat pad
14. Regulation of mammary gland growth and morphogenesis by the mammary fat pad: A species comparison
15. Multiple hormone interactions in the developmental biology of the mammary gland
16. Regulation of mammary epithelial cell growth in mice and rats
17. Hormones and mammary carcinogenesis in mice, rats, and humans: A unifying hypothesis
18. Postnatal mammary gland morphogenesis
19. Progestins and antiprogestins in mammary tumor growth and metastasis
20. The molecular biology of RU486: Is there a role for antiprogestins in the treatment of breast cancer
21. Prolactin involvement in breast cancer
22. Should prolactin be reconsidered as a therapeutic target in human breast cancer?
23. Plasma prolactin levels and subsequent risk of breast cancer in postmenopausal women
24. A reappraisal of progesterone action in the mammary gland
25. EGF receptor regulation in normal mouse mammary gland
26. Tissue distribution and quantitative analysis of estrogen receptor-α (ER-α) and estrogen receptor-β (ER-β) messenger ribonucleic acid in the wild-type and ER-α-knockout mouse
27. Direct action of 17 β-estradiol on mouse mammary ducts analyzed by sustained release implants and steroid autoradiography
28. Estrogen receptor-negative epithelial cells in mouse mammary gland development and growth
29. Estrogen receptors-α and -β in the rodent mammary gland
30. Stimulation of mammary epithelial cell growth in vitro: Interaction of epidermal growth factor and mammogenic hormones
31. The lack of effect of phenol red and estradiol on the growth response of human, rat and mouse mammary epithelial cells in primary culture
32. Elucidation of a role for stromal steroid hormone receptors in mammary gland growth and development using tissue recombinants
33. Mechanism of estrogen action: Lessons from the estrogen receptor-α knockout mouse
34. Regulation of estrogen and progesterone receptor levels in mouse mammary epithelial cells grown in serum-free collagen gel cultures
35. Induction of mammary gland development in estrogen receptor-α knockout mice
36. Local versus systemically mediated effects of estrogen on normal mammary epithelial cell deoxyribonucleic acid synthesis
37. Prolactin controls mammary gland development via direct and indirect mechanisms
38. Prolactin (PRL) receptor gene expression in mouse adipose tissue: Increases during lactation and in PRL-transgenic mice
39. In situ localization of progesterone receptors in normal mouse mammary glands: Absence of receptors in connective and adipose stroma and heterogeneous distribution in the epithelium
40. Progesterone induces side-branching of the ductal epithelium in the mammary glands of peripubertal mice
41. Progesterone signaling and mammary gland morphogenesis
42. HGF/SF in mammary epithelial growth and morphogenesis: In vitro and in vivo models
43. Roles of hepatocyte growth factor/scatter factor and transforming growth factor-β1 in mammary gland ductal morphogenesis
44. Sequential requirement of hepatocyte growth factor and neuregulin in the morphogenesis and differentiation of the mammary gland
45. HGF/SF: A potent cytokine for mammary growth, morphogenesis and development
46. Identification of mouse mammary fibroblast-derived mammary growth factor as hepatocyte growth factor
47. Mammary fibroblast-derived hepatocyte growth factor and mammogenic hormones stimulate the growth of mouse mammary epithelial cells in primary culture
48. Reconstitution of mammary gland development in vitro: Requirement of c-MET and c-ErbB2 signaling for branching and alveolar morphogenesis
49. Modulation of hepatocyte growth factor and c-MET in the rat mammary gland during pregnancy, lactation, and involution
50. Dynamic expression and activation of ErbB receptors in the developing mouse mammary gland
51. Modulation of hepatocyte growth factor gene expression by estrogen in mouse ovary
52. Transcriptional regulation of the hepatocyte growth factor gene by the nuclear receptors chicken ovalbumin upstream promoter transcription factor and estrogen receptor
53. Up-regulation of hepatocyte growth factor gene expression by interleukin-1 in human skin fibroblasts
54. Novel function of prostaglandins as inducers of gene expression of HGF and putative mediators of tissue regeneration
55. Induction of hepatocyte growth factor in human skin fibroblasts by epidermal growth factor, platelet-derived growth factor and fibroblast growth factor
56. Modulation of c-MET proto-oncogene (HGF receptor) mRNA abundance by cytokines and hormones: Evidence for rapid decay of the 8 kb c-MET transcript
57. Regulation of HGF and HGFR gene expression
58. Induction of hepatocyte growth factor in fibroblasts by tumor-derived factors affects invasive growth of tumor cells: In vitro analysis of tumor-stromal interactions
59. Negative regulation of hepatocyte growth factor gene expression in human lung fibroblasts and leukemic cells by transforming growth factor-β1 and glucocorticoids
60. Overexpression of a kinase-deficient transforming growth factor-β type II receptor in mouse mammary stroma results in increased epithelial branching
61. IGF and insulin action in the mammary gland: Lessons from transgenic and knockout models
62. The insulin-like growth factors (IGFs) and IGF binding proteins in postnatal development of murine mammary glands
63. IGF-I: An essential factor in terminal end bud formation and ductal morphogenesis
64. Evidence that the mammary fat pad mediates the action of growth hormone in mammary gland development
65. Differential expression of the growth hormone receptor and growth hormone-binding protein in epithelia and stroma of the mouse mammary gland at various physiological stages
66. Estradiol enhances the stimulatory effect of insulin-like growth factor-I (IGF-I) on mammary development and growth hormone-induced IGF-I messenger ribonucleic acid
67. The insulin-like growth factors (IGF) and IGF type I receptor during postnatal growth of the murine mammary gland: Sites of messenger ribonucleic acid expression and potential functions
68. Role of growth hormone and insulin-like growth factor-I in mammary development
69. Somatomedin-C substitutes for insulin for the growth of mammary epithelial cells from normal virgin mice in serum-free collagen gel cell culture
70. Function of the IGF-I receptor in breast cancer
71. Insulin-like growth factor binding proteins (IGFBPs) in breast cancer
72. Expression of a lactogen-dependent insulin-like growth factor-binding protein in cultured mouse mammary epithelial cells
73. Inhibins and activins regulate mammary epithelial cell differentiation through mesenchymal-epithelial interactions
74. Immunolocalization of inhibin in the mammary gland of rats treated with HCG
75. Inhibin/activin subunits and activin receptors in human breast cell-lines and lactating rat mammary glands
76. Physiological bases of breast cancer prevention
77. Localization and quantification of Wnt-2 gene expression in mouse mammary development
78. Developmental and hormonal regulation of Wnt gene expression in the mouse mammary gland
79. Tyrosine kinase signalling in breast cancer: Fibroblast growth factors and their receptors
80. A role for fibroblast growth factor signaling in the lobuloalveolar development of the mammary gland
81. Differential temporal and spatial gene expression of fibroblast growth factor family members during mouse mammary gland development
82. Pattern of expression of the KGF receptor and its ligands KGF and FGF-10 during postnatal mouse mammary gland development
83. Basic fibroblast growth factor stimulates the growth and inhibits casein accumulation in mouse mammary epithelial cells in vitro
84. In vivo and in vitro evidence of basic fibroblast growth factor action in mouse mammary gland development
85. Keratinocyte growth factor as a cytokine that mediates mesenchymal-epithelial interaction
86. Pattern of keratinocyte growth factor and keratinocyte growth factor receptor expression during mouse fetal development suggests a role in mediating morphogenetic mesenchymal-epithelial interactions
87. FGF-FGFR signaling in vertebrate organogenesis
88. Structure and expression of the rat mRNA encoding a novel member of the fibroblast growth factor family
89. Mouse fibroblast growth factor-10: cDNA cloning, protein characterization, and regulation of mRNA expression
90. Structure and expression of human fibroblast growth factor-10
91. Fibroblast growth factor-10 (FGF-10) and branching morphogenesis in the embryonic mouse lung
92. Characterization of recombinant human fibroblast growth factor (FGF)-10 reveals functional similarities with keratinocyte growth factor (FGF-7)
93. Keratinocyte growth factor is required for hair development but not for wound healing
94. FGF-10 is essential for limb and lung formation
95. FGF-10 is a growth factor for preadipocytes in white adipose tissue
96. Immunohistochemical distribution of epimorphin in human and mouse tissues
97. Epimorphin functions as a key morphoregulator for mammary epithelial cells
98. Influences of keratinocyte-fibroblast interaction on the expression of epimorphin by fibroblasts in vitro
99. The role of TGF-β in patterning and growth of the mammary ductal tree
100. Dominant-negative interference of the transforming growth factor-β type II receptor in mammary gland epithelium results in alveolar hyperplasia and differentiation in virgin mice
101. The primary culture of mouse adipocyte precursor cells in defined medium
102. Transforming growth factor-β (TGF-β) inhibits the differentiation of human adipocyte precursor cells in primary culture
103. Autocrine secretion of TGF-β1 and TGF-β2 by preadipocytes and adipocytes: A potent negative regulator of adipocyte differentiation and proliferation of mammary carcinoma cells
104. Decrease in transforming growth factor-β1 binding during differentiation of rat adipocyte precursors in primary culture
105. Epithelium-dependent extracellular matrix synthesis in transforming growth factor-β1-growth-inhibited mouse mammary gland
106. Induction of transforming growth factor-β by the antiestrogens droloxifene, tamoxifen, and toremifene in MCF-7 cells
107. Role of TGF-β in the anti-estrogen response/resistance of human breast cancer
108. Complex role of tumor cell transforming growth factor (TGF)-β on breast carcinoma progression
109. Latency and activation in the control of TGF-β
110. Colony stimulating factor 1 is required for mammary gland development during pregnancy
111. Postnatal mammary gland development requires macrophages and eosinophils
112. The role of CSF-1 in normal and neoplastic breast physiology
113. Expression of CSF-I and CSF-I receptor by normal lactating mammary epithelial cells
114. Regulation of rat mammary epithelial cell proliferation and differentiation by tumor necrosis factor-α
115. Tumor necrosis factor-α: A multifunctional regulator of mammary gland development
116. Breast cancer and the role of cytokines in regulating estrogen synthesis: An emerging hypothesis
117. Stromal cells are critical targets in the regulation of mammary ductal morphogenesis by parathyroid hormone-related protein
118. Rescue of the parathyroid hormone-related protein knockout mouse demonstrates that parathyroid hormone-related protein is essential for mammary gland development
119. The mammary gland: A model for development
120. Regulation of mammary gland development by tissue interaction
121. Parathyroid hormone-related protein signaling is necessary for sexual dimorphism during embryonic mammary development
122. Targeted inactivation of the EGF and amphiregulin genes reveals distinct roles for EGF receptor ligands in mouse mammary gland development
123. Growth factors in breast cancer
124. EGF-related peptides in the pathophysiology of the mammary gland
125. EGF-related peptides and their receptors in mammary gland development
126. The epidermal growth factor receptor in breast cancer
127. Hormonal regulation of type I receptor tyrosine kinase expression in the mammary gland
128. Detection and location of amphiregulin and cripto-1 expression in the developing postnatal mouse mammary gland
129. Transforming growth factor-α messenger RNA localization in the developing adult rat and human mammary gland by in situ hybridization
130. Detection and location of amphiregulin and cripto-1 expression in the developing postnatal mouse mammary gland
131. Estrogen enhances epidermal growth factor-induced DNA synthesis in mammary epithelial cells
132. Role of epidermal growth factor in the acquisition of ovarian steroid hormone responsiveness in the normal mouse mammary gland
133. Activation and function of the epidermal growth factor receptor and ErbB2 during mammary gland morphogenesis
134. Signaling through the stromal epidermal growth factor receptor is necessary for mammary ductal development
135. Changes in epidermal growth factor concentrations of submandibular gland, plasma, and urine of normal and sialoadenectomized female mice during various reproductive stages
136. Evidence for the involvement of the submandibular gland epidermal growth factor in mouse mammary tumorogenesis
137. Large induction of keratinocyte growth factor expression by serum growth factors and pro-inflammatory cytokines in cultured fibroblasts
138. Adipocyte-epithelial interactions regulate the in vitro development of normal mammary epithelial cells
139. Bioactive lysophospholipids and their G-protein-coupled receptors
140. The FGF family of growth factors and oncogenes
141. Purification and characterization of a newly identified growth factor specific for epithelial cells
142. Keratinocyte growth factor
143. Expression of keratinocyte growth factor and its receptor in human breast cancer
144. Detection of aromatase and keratinocyte growth factor expression in breast tumors using reverse transcription-polymerase chain reaction
145. Hepatocyte growth factor (HGF), keratinocyte growth factor (KGF), and their receptors in human breast cells and tissues: Alternative receptors
146. Mammogenic hormones differentially modulate keratinocyte growth factor (KGF)-induced proliferation and KGF receptor expression in cultured mouse mammary gland epithelium
147. Estrogen treatment in vivo increases keratinocyte growth factor expression in the mammary gland
148. Fibroblast growth factor-10: A second candidate stromal to epithelial cell andromedin in prostate
149. FGF-10 is a chemotactic factor for distal epithelial buds during lung development
150. Attenuation and loss of hormonal modulation of KGF (FGF-7)/KGF receptor expression and mitogenesis during mammary tumor progression
151. Genetically engineered mouse models of mammary intraepithelial neoplasia
152. Mammary gland neoplasia: Insights from transgenic mouse models
153. Growth factors, apoptosis, and survival of mammary epithelial cells
154. Transgenic mouse models of breast cancer
155. Regulation of proliferation, invasion and growth factor synthesis in breast cancer by steroids
156. Transgenic mouse models of tumor angiogenesis: The angiogenic switch, its molecular controls, and prospects for preclinical therapeutic models
157. Oncogenes and angiogenesis: Signaling three-dimensional tumor growth
158. Growth factor and sex steroid interactions in breast cancer
159. The role of stroma in breast carcinoma growth in vivo
160. Cellular changes involved in conversion of normal to malignant breast: Importance of the stromal reaction
161. Structural cues from the tissue microenvironment are essential determinants of the human mammary epithelial cell phenotype
162. Tissue structure, nuclear organization, and gene expression in normal and malignant breast
163. The potential influence of radiation-induced microenvironments in neoplastic progression
164. Earlier appearance of murine mammary tumor virus-associated antigens in duct-alveolus nodules induced by transplantation of fetal salivary mesenchyme into C3H mouse mammary glands
165. Accelerated mammary cancer development by fetal salivary mesenchyma isografted to adult mouse mammary epithelium
166. Acceleration of mammary cancer development by grafting of fetal mammary mesenchymes in C3H mice
167. Transformed growth phenotype of mouse mammary epithelium in primary culture induced by specific fetal mesenchymes
168. In vitro transformation of mouse mammary epithelial cells grown serum-free inside collagen gels
169. Neoplastic transformation of mouse mammary epithelial cells by in vitro exposure to N-methyl-N-nitrosourea
170. Induction of mammary carcinomas by N-methyl-N-nitrosourea in ovariectomized rats treated with epidermal growth factor
171. Refractoriness to mammary tumorigenesis in parous rats: Is it caused by persistent changes in the hormonal environment or permanent biochemical alterations in the mammary epithelia?
172. A transplantable pregnancy-dependent mammary tumor line (TPDMT-4) in strain DDD mice
173. Accelerated progression to autonomy of a pregnancy-dependent mouse mammary tumor (TPDMT-4) by hormones
174. Pregnancy-dependent to ovarian-independent progression in mammary tumors delineated in primary culture: Changes in signal transduction, growth factor regulation
175. Basic fibroblast growth factor confers a less malignant phenotype in MDA-MB-231 human breast cancer cells
176. Localization of basic fibroblast growth factor and transforming growth factor-β1 in the human mammary gland
177. Fibroblast growth factor receptor-2 limits and receptor-1 accelerates tumorigenicity of prostate epithelial cells
178. Inhibition of growth of malignant rat prostate tumor cells by restoration of fibroblast growth factor receptor-2
179. Expression of FGF and FGF receptor genes in human breast cancer
180. Fibroblast growth factor overexpressing breast carcinoma cells as models of angiogenesis and metastasis
181. Expression of epidermal growth factor-related proteins in the aged adult mouse mammary gland and their relationship to tumorigenesis
182. Role of IGF-I in normal mammary development
183. Regulation of mammary morphogenesis: Evidence for extracellular matrix-mediated inhibition of ductal budding by transforming growth factor-β1
184. Regulated expression and growth inhibitory effects of transforming growth factor-β isoforms in mouse mammary gland development
185. In vivo inhibition of keratinocyte growth factor receptor expression by estrogen and antagonism by progesterone in the mouse mammary gland