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Volumn 151, Issue 1-2, 1999, Pages 79-87

Should prolactin be reconsidered as a therapeutic target in human breast cancer?

Author keywords

16K prolactin; Angiogenesis; Antagonist; Breast cancer; Prolactin; Prolactin receptor

Indexed keywords

BROMOCRIPTINE; DOPAMINE RECEPTOR STIMULATING AGENT; PROLACTIN; PROLACTIN RECEPTOR; SOMATOSTATIN;

EID: 0033603020     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0303-7207(99)00023-4     Document Type: Article
Times cited : (64)

References (71)
  • 1
    • 0028884033 scopus 로고
    • PD 098059 is a specific inhibitor of the activation of mitogen- activated protein kinase kinase in vitro and in vivo
    • Alessi D.R., Cuenda A., Cohen P., Dudley D.T., Saltiel A.R. PD 098059 is a specific inhibitor of the activation of mitogen- activated protein kinase kinase in vitro and in vivo. J. Biol. Chem. 270:1995;27489-27494.
    • (1995) J. Biol. Chem. , vol.270 , pp. 27489-27494
    • Alessi, D.R.1    Cuenda, A.2    Cohen, P.3    Dudley, D.T.4    Saltiel, A.R.5
  • 3
    • 0030451788 scopus 로고    scopus 로고
    • Extrapituitary prolactin: Distribution, regulation, functions, and clinical aspects
    • Ben-Jonathan N., Mershon J.L., Allen D.L., Steinmetz R.W. Extrapituitary prolactin: distribution, regulation, functions, and clinical aspects. Endocr. Rev. 17:1996;639-669.
    • (1996) Endocr. Rev. , vol.17 , pp. 639-669
    • Ben-Jonathan, N.1    Mershon, J.L.2    Allen, D.L.3    Steinmetz, R.W.4
  • 4
    • 0028277432 scopus 로고
    • Characterization of an up-stream promoter directing extrapituitary expression of the human prolactin gene
    • Berwaer M., Martial J.A., Davis J.R. Characterization of an up-stream promoter directing extrapituitary expression of the human prolactin gene. Mol. Endocrinol. 8:1994;635-642.
    • (1994) Mol. Endocrinol. , vol.8 , pp. 635-642
    • Berwaer, M.1    Martial, J.A.2    Davis, J.R.3
  • 5
    • 0032460226 scopus 로고    scopus 로고
    • Prolactin and its receptor: Actions, signal transduction pathways and phenotypes observed in prolactin receptor knockout mice
    • Bole-Feysot C., Goffin V., Edery M., Binart N., Kelly P.A. Prolactin and its receptor: actions, signal transduction pathways and phenotypes observed in prolactin receptor knockout mice. Endocr. Rev. 19:1998;225-268.
    • (1998) Endocr. Rev. , vol.19 , pp. 225-268
    • Bole-Feysot, C.1    Goffin, V.2    Edery, M.3    Binart, N.4    Kelly, P.A.5
  • 7
    • 0028357212 scopus 로고
    • In vitro and in vivo studies of antagonistic effects of human growth hormone analogs
    • Chen W.Y., Chen N.Y., Yun J., Wagner T.E., Kopchick J.J. In vitro and in vivo studies of antagonistic effects of human growth hormone analogs. J. Biol. Chem. 269:1994;15892-15897.
    • (1994) J. Biol. Chem. , vol.269 , pp. 15892-15897
    • Chen, W.Y.1    Chen, N.Y.2    Yun, J.3    Wagner, T.E.4    Kopchick, J.J.5
  • 8
    • 0031790107 scopus 로고    scopus 로고
    • Development of recombinant human prolactin receptor antagonists by molecular mimicry of the phosphorylated hormone
    • Chen T.J., Kuo C.B., Tsai K.F., Liu J.W., Chen D.Y., Walker A.M. Development of recombinant human prolactin receptor antagonists by molecular mimicry of the phosphorylated hormone. Endocrinology. 139:1998;609-616.
    • (1998) Endocrinology , vol.139 , pp. 609-616
    • Chen, T.J.1    Kuo, C.B.2    Tsai, K.F.3    Liu, J.W.4    Chen, D.Y.5    Walker, A.M.6
  • 9
    • 0026566153 scopus 로고
    • A specific, high affinity, saturable binding site for the 16-kilodalton fragment of prolactin on capillary endothelial cells
    • Clapp C., Weiner R.I. A specific, high affinity, saturable binding site for the 16-kilodalton fragment of prolactin on capillary endothelial cells. Endocrinology. 130:1992;1380-1386.
    • (1992) Endocrinology , vol.130 , pp. 1380-1386
    • Clapp, C.1    Weiner, R.I.2
  • 10
    • 0027236943 scopus 로고
    • The 16-kilodalton N-terminal fragment of human prolactin is a potent inhibitor of angiogenesis
    • Clapp C., Martial J.A., Guzman R.C., Rentier-Delrue F., Weiner R.I. The 16-kilodalton N-terminal fragment of human prolactin is a potent inhibitor of angiogenesis. Endocrinology. 133:1993;1292-1299.
    • (1993) Endocrinology , vol.133 , pp. 1292-1299
    • Clapp, C.1    Martial, J.A.2    Guzman, R.C.3    Rentier-Delrue, F.4    Weiner, R.I.5
  • 12
    • 0030621563 scopus 로고    scopus 로고
    • Prolactin as an autocrine/paracrine factor in breast cancer
    • Clevenger C.V., Plank T.L. Prolactin as an autocrine/paracrine factor in breast cancer. J. Mamm. Gland. Biol. Neopl. 2:1997;59-68.
    • (1997) J. Mamm. Gland. Biol. Neopl. , vol.2 , pp. 59-68
    • Clevenger, C.V.1    Plank, T.L.2
  • 13
    • 0029071065 scopus 로고
    • Activation of mitogen-activated protein kinases by vascular endothelial growth factor and basic fibroblasts growth factor in capillary endothelial cells is inhibited by the anti-angiogenic factor 16-kDa N-terminal fragment of prolactin
    • D'Angelo G., Struman I., Martial J.A., Weiner R.I. Activation of mitogen-activated protein kinases by vascular endothelial growth factor and basic fibroblasts growth factor in capillary endothelial cells is inhibited by the anti-angiogenic factor 16-kDa N-terminal fragment of prolactin. Proc. Natl. Acad. Sci. USA. 92:1995;6374-6378.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 6374-6378
    • D'Angelo, G.1    Struman, I.2    Martial, J.A.3    Weiner, R.I.4
  • 14
    • 0030840464 scopus 로고    scopus 로고
    • STATs and gene regulation
    • Darnell J.E. STATs and gene regulation. Science. 277:1997;1630-1635.
    • (1997) Science , vol.277 , pp. 1630-1635
    • Darnell, J.E.1
  • 15
    • 0029817335 scopus 로고    scopus 로고
    • Activation of raf-1 MEK, and MAP kinase in prolactin responsive mammary cells
    • Das R., Vonderhaar B.K. Activation of raf-1 MEK, and MAP kinase in prolactin responsive mammary cells. Breast Cancer Res. Treat. 40:1996a;141-149.
    • (1996) Breast Cancer Res. Treat. , vol.40 , pp. 141-149
    • Das, R.1    Vonderhaar, B.K.2
  • 16
    • 0029834929 scopus 로고    scopus 로고
    • Involvement of SHC, GRB2, SOS and RAS in prolactin signal transduction in mammary epithelial cells
    • Das R., Vonderhaar B.K. Involvement of SHC, GRB2, SOS and RAS in prolactin signal transduction in mammary epithelial cells. Oncogene. 13:1996b;1139-1145.
    • (1996) Oncogene , vol.13 , pp. 1139-1145
    • Das, R.1    Vonderhaar, B.K.2
  • 19
    • 0026598960 scopus 로고
    • Human growth hormone and extracellular domain of its receptor: Crystal structure of the complex
    • De Vos A.M., Ultsch M., Kossiakoff A.A. Human growth hormone and extracellular domain of its receptor: crystal structure of the complex. Science. 255:1992;306-312.
    • (1992) Science , vol.255 , pp. 306-312
    • De Vos, A.M.1    Ultsch, M.2    Kossiakoff, A.A.3
  • 20
    • 0027469936 scopus 로고
    • The transcription factor Pit-1/GHF-1 is expressed in hemopoietic and lymphoid tissues
    • Delhase M., Vergani P., Malur A., Hooghe-Peters E.L., Hooghe R.J. The transcription factor Pit-1/GHF-1 is expressed in hemopoietic and lymphoid tissues. Eur. J. Immunol. 23:1993a;951-955.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 951-955
    • Delhase, M.1    Vergani, P.2    Malur, A.3    Hooghe-Peters, E.L.4    Hooghe, R.J.5
  • 22
    • 0025109558 scopus 로고
    • Human prolactin gene expression. the use of an alternative non coding exon in decidua and the IM-9-P3 lymphoblast cell line
    • DiMattia G.E., Gellersen B., Duckworth M.L., Friesen H.G. Human prolactin gene expression. the use of an alternative non coding exon in decidua and the IM-9-P3 lymphoblast cell line. J. Biol. Chem. 265:1990;16412-16421.
    • (1990) J. Biol. Chem. , vol.265 , pp. 16412-16421
    • Dimattia, G.E.1    Gellersen, B.2    Duckworth, M.L.3    Friesen, H.G.4
  • 23
    • 0030666921 scopus 로고    scopus 로고
    • Mitogenic signaling of insulin-like growth factor I in MCF-7 human breast cancer cells requires phosphatidylinositol 3-kinase and is independent of mitogen-activated protein kinase
    • Dufourny B., Alblas J., van Teeffelen H.A., van Schaik F.M., van der Burg B., Steenbergh P.H., Sussenbach J.S. Mitogenic signaling of insulin-like growth factor I in MCF-7 human breast cancer cells requires phosphatidylinositol 3-kinase and is independent of mitogen-activated protein kinase. J. Biol. Chem. 272:1997;31163-31171.
    • (1997) J. Biol. Chem. , vol.272 , pp. 31163-31171
    • Dufourny, B.1    Alblas, J.2    Van Teeffelen, H.A.3    Van Schaik, F.M.4    Van Der Burg, B.5    Steenbergh, P.H.6    Sussenbach, J.S.7
  • 24
    • 0025949596 scopus 로고
    • The 16K fragment of rat prolactin specifically inhibits basal or FGF stimulated growth of capillary endothelial cells
    • Ferrara N., Clapp C., Weiner R.I. The 16K fragment of rat prolactin specifically inhibits basal or FGF stimulated growth of capillary endothelial cells. Endocrinology. 129:1991;896-906.
    • (1991) Endocrinology , vol.129 , pp. 896-906
    • Ferrara, N.1    Clapp, C.2    Weiner, R.I.3
  • 25
  • 26
    • 0027536507 scopus 로고
    • Mechanism-based design of prolactin receptor antagonists
    • Fuh G., Colosi P., Wood W.I., Wells J.A. Mechanism-based design of prolactin receptor antagonists. J. Biol. Chem. 268:1993;5376-5381.
    • (1993) J. Biol. Chem. , vol.268 , pp. 5376-5381
    • Fuh, G.1    Colosi, P.2    Wood, W.I.3    Wells, J.A.4
  • 27
    • 0029012232 scopus 로고
    • Prolactin receptor antagonists that inhibit the growth of breast cancer cell lines
    • Fuh G., Wells J.A. Prolactin receptor antagonists that inhibit the growth of breast cancer cell lines. J. Biol. Chem. 270:1995;13133-13137.
    • (1995) J. Biol. Chem. , vol.270 , pp. 13133-13137
    • Fuh, G.1    Wells, J.A.2
  • 28
    • 0028939826 scopus 로고
    • Clinical importance of the determination of tumor angiogenesis in breast carcinoma: Much more than a new prognostic tool
    • Gasparini G., Harris A.L. Clinical importance of the determination of tumor angiogenesis in breast carcinoma: much more than a new prognostic tool. J. Clin. Oncol. 13:1995;765-782.
    • (1995) J. Clin. Oncol. , vol.13 , pp. 765-782
    • Gasparini, G.1    Harris, A.L.2
  • 29
    • 0028258969 scopus 로고
    • Nonpituitary human prolactin gene transcription is independent of Pit-1 and differentially controlled in lymphocytes and in endometrial stroma
    • Gellersen B., Kempf R., Telgmann R., DiMattia G.E. Nonpituitary human prolactin gene transcription is independent of Pit-1 and differentially controlled in lymphocytes and in endometrial stroma. Mol. Endocrinol. 8:1994;356-373.
    • (1994) Mol. Endocrinol. , vol.8 , pp. 356-373
    • Gellersen, B.1    Kempf, R.2    Telgmann, R.3    Dimattia, G.E.4
  • 30
    • 84960569586 scopus 로고
    • Neovascularization induced by intraocular xenografts of normal, preneoplastic, and neoplastic mouse mammary tissues
    • Gimbrone M.A.J., Gullino P.M. Neovascularization induced by intraocular xenografts of normal, preneoplastic, and neoplastic mouse mammary tissues. J. Natl. Cancer Inst. 56:1976;305-318.
    • (1976) J. Natl. Cancer Inst. , vol.56 , pp. 305-318
    • Gimbrone, M.A.J.1    Gullino, P.M.2
  • 31
    • 0029005357 scopus 로고
    • Prolactin synthesis and secretion by human breast cancer cells
    • Ginsburg E., Vonderhaar B.K. Prolactin synthesis and secretion by human breast cancer cells. Cancer Res. 55:1995;2591-2595.
    • (1995) Cancer Res. , vol.55 , pp. 2591-2595
    • Ginsburg, E.1    Vonderhaar, B.K.2
  • 33
    • 0029972947 scopus 로고    scopus 로고
    • Antagonistic properties of human prolactin analogs that show paradoxical agonistic activity in the Nb2 bioassay
    • Goffin V., Kinet S., Ferrag F., Binart N., Martial J.A., Kelly P.A. Antagonistic properties of human prolactin analogs that show paradoxical agonistic activity in the Nb2 bioassay. J. Biol. Chem. 271:1996a;16573-16579.
    • (1996) J. Biol. Chem. , vol.271 , pp. 16573-16579
    • Goffin, V.1    Kinet, S.2    Ferrag, F.3    Binart, N.4    Martial, J.A.5    Kelly, P.A.6
  • 34
    • 0029825056 scopus 로고    scopus 로고
    • Sequence-function relationships within the expanding family of prolactin, growth hormone, placental lactogen and related proteins in mammals
    • Goffin V., Shiverick K.T., Kelly P.A., Martial J.A. Sequence-function relationships within the expanding family of prolactin, growth hormone, placental lactogen and related proteins in mammals. Endocr. Rev. 17:1996b;385-410.
    • (1996) Endocr. Rev. , vol.17 , pp. 385-410
    • Goffin, V.1    Shiverick, K.T.2    Kelly, P.A.3    Martial, J.A.4
  • 35
    • 0030621547 scopus 로고    scopus 로고
    • The prolactin/growth hormone receptor family: Structure/function relationships
    • Goffin V., Kelly P.A. The prolactin/growth hormone receptor family: structure/function relationships. J.Mamm. Gland. Biol. Neopl. 2:1997;7-17.
    • (1997) J.Mamm. Gland. Biol. Neopl. , vol.2 , pp. 7-17
    • Goffin, V.1    Kelly, P.A.2
  • 36
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • Hanahan D., Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell. 86:1996;353-364.
    • (1996) Cell , vol.86 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 38
    • 0032568817 scopus 로고    scopus 로고
    • Novel recombinant analogues of bovine placental lactogen: G133K and G133R provide a tool to understand the difference between the action of prolactin and growth hormone receptors
    • Helman D., Staten N.R., Grosclaude J., Daniel N., Nespoulous C., Djiane J., Gertler A. Novel recombinant analogues of bovine placental lactogen: G133K and G133R provide a tool to understand the difference between the action of prolactin and growth hormone receptors. J. Biol. Chem. 273:1998;16067-16074.
    • (1998) J. Biol. Chem. , vol.273 , pp. 16067-16074
    • Helman, D.1    Staten, N.R.2    Grosclaude, J.3    Daniel, N.4    Nespoulous, C.5    Djiane, J.6    Gertler, A.7
  • 39
    • 0028921573 scopus 로고
    • Jaks and Stats in signaling by the cytokine receptor superfamily
    • Ihle J.N., Kerr I.M. Jaks and Stats in signaling by the cytokine receptor superfamily. Trends Genet. 11:1995;69-74.
    • (1995) Trends Genet. , vol.11 , pp. 69-74
    • Ihle, J.N.1    Kerr, I.M.2
  • 40
    • 84995826606 scopus 로고
    • Receptor dimerization determines the effect of growth hormone in primary rat adipocytes and cultured human IM-9 lymphocytes
    • Ilondo M.M., Damholt A.B., Cunningham B.C., Wells J.A., De Meyts P., Shymko R.M. Receptor dimerization determines the effect of growth hormone in primary rat adipocytes and cultured human IM-9 lymphocytes. Endocrinology. 134:1994;2397-2403.
    • (1994) Endocrinology , vol.134 , pp. 2397-2403
    • Ilondo, M.M.1    Damholt, A.B.2    Cunningham, B.C.3    Wells, J.A.4    De Meyts, P.5    Shymko, R.M.6
  • 41
    • 0032540288 scopus 로고    scopus 로고
    • Insulin receptor substrate-1 is the predominant signaling molecule activated by insulin-like growth factor-I, insulin, and interleukin-4 in estrogen receptor-positive human breast cancer cells
    • Jackson J.G., White M.F., Yee D. Insulin receptor substrate-1 is the predominant signaling molecule activated by insulin-like growth factor-I, insulin, and interleukin-4 in estrogen receptor-positive human breast cancer cells. J. Biol. Chem. 273:1998;9994-10003.
    • (1998) J. Biol. Chem. , vol.273 , pp. 9994-10003
    • Jackson, J.G.1    White, M.F.2    Yee, D.3
  • 42
    • 0027375476 scopus 로고
    • William L. McGuire Memorial Symposium. Estrogen and progestin effects in human breast carcinogenesis
    • King R.J. William L. McGuire Memorial Symposium. Estrogen and progestin effects in human breast carcinogenesis. Breast Cancer Res. Treat. 27:1993;3-15.
    • (1993) Breast Cancer Res. Treat. , vol.27 , pp. 3-15
    • King, R.J.1
  • 43
    • 0028174290 scopus 로고
    • Prolactin-induced proliferation of Nb2 cells involves tyrosine phosphorylation of the prolactin receptor and its associated tyrosine kinase
    • Lebrun J.J., Ali S., Sofer L., Ullrich A., Kelly P.A. Prolactin-induced proliferation of Nb2 cells involves tyrosine phosphorylation of the prolactin receptor and its associated tyrosine kinase. J. Biol. Chem. 269:1994;14021-14026.
    • (1994) J. Biol. Chem. , vol.269 , pp. 14021-14026
    • Lebrun, J.J.1    Ali, S.2    Sofer, L.3    Ullrich, A.4    Kelly, P.A.5
  • 44
    • 0028956974 scopus 로고
    • Proline-rich sequence-mediated JAK2 association to the prolactin receptor is required but not sufficient for signal transduction
    • Lebrun J.J., Ali S., Ullrich A., Kelly P.A. Proline-rich sequence-mediated JAK2 association to the prolactin receptor is required but not sufficient for signal transduction. J. Biol. Chem. 270:1995;10664-10670.
    • (1995) J. Biol. Chem. , vol.270 , pp. 10664-10670
    • Lebrun, J.J.1    Ali, S.2    Ullrich, A.3    Kelly, P.A.4
  • 45
    • 0031730107 scopus 로고    scopus 로고
    • Inhibition of urokinase activity by the antiangiogenic factor 16K prolactin: Activation of plasminogen activator inhibitor 1 expression
    • Lee H., Struman I., Clapp C., Martial J., Weiner R.I. Inhibition of urokinase activity by the antiangiogenic factor 16K prolactin: activation of plasminogen activator inhibitor 1 expression. Endocrinology. 139:1998;3696-3703.
    • (1998) Endocrinology , vol.139 , pp. 3696-3703
    • Lee, H.1    Struman, I.2    Clapp, C.3    Martial, J.4    Weiner, R.I.5
  • 50
    • 0020700098 scopus 로고
    • Physiological concentrations of prolactin can promote the growth of human breast tumor cells in culture
    • Malarkey W.B., Kennedy M., Allred L.E., Milo G. Physiological concentrations of prolactin can promote the growth of human breast tumor cells in culture. J. Clin. Endocrinol. Metab. 56:1983;673-677.
    • (1983) J. Clin. Endocrinol. Metab. , vol.56 , pp. 673-677
    • Malarkey, W.B.1    Kennedy, M.2    Allred, L.E.3    Milo, G.4
  • 52
    • 0029156867 scopus 로고
    • Prolactin is a local growth factor in rat mammary tumors
    • Mershon J., Sall W., Mitchner N., Ben-Jonathan N. Prolactin is a local growth factor in rat mammary tumors. Endocrinology. 136:1995;3619-3623.
    • (1995) Endocrinology , vol.136 , pp. 3619-3623
    • Mershon, J.1    Sall, W.2    Mitchner, N.3    Ben-Jonathan, N.4
  • 55
    • 0030978808 scopus 로고    scopus 로고
    • Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides: Tyrphostin AG490 inhibits Stat3 activation and growth of mycosis fungoides tumor cell lines
    • Nielsen M., Kaltoft K., Nordahl M., Ropke C., Geisler C., Mustelin T., Dobson P., Svejgaard A., Odum N. Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides: tyrphostin AG490 inhibits Stat3 activation and growth of mycosis fungoides tumor cell lines. Proc. Natl. Acad. Sci. USA. 94:1997;6764-6769.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 6764-6769
    • Nielsen, M.1    Kaltoft, K.2    Nordahl, M.3    Ropke, C.4    Geisler, C.5    Mustelin, T.6    Dobson, P.7    Svejgaard, A.8    Odum, N.9
  • 57
    • 0030785696 scopus 로고    scopus 로고
    • Tyrphostin AG 494 blocks Cdk2 activation
    • Osherov N., Levitzki A. Tyrphostin AG 494 blocks Cdk2 activation. FEBS Lett. 410:1997;187-190.
    • (1997) FEBS Lett. , vol.410 , pp. 187-190
    • Osherov, N.1    Levitzki, A.2
  • 58
    • 0026750040 scopus 로고
    • Expression of prolactin and its receptor in human lymphoid cells
    • Pellegrini I., Lebrun J.J., Ali S., Kelly P.A. Expression of prolactin and its receptor in human lymphoid cells. Mol. Endocrinol. 6:1992;1023-1031.
    • (1992) Mol. Endocrinol. , vol.6 , pp. 1023-1031
    • Pellegrini, I.1    Lebrun, J.J.2    Ali, S.3    Kelly, P.A.4
  • 59
    • 0030916985 scopus 로고    scopus 로고
    • The last proline of Box 1 is essential for association with JAK2 and functional activation of the prolactin receptor
    • Pezet A., Buteau H., Kelly P.A., Edery M. The last proline of Box 1 is essential for association with JAK2 and functional activation of the prolactin receptor. Mol. Cell. Endocrinol. 129:1997;199-208.
    • (1997) Mol. Cell. Endocrinol. , vol.129 , pp. 199-208
    • Pezet, A.1    Buteau, H.2    Kelly, P.A.3    Edery, M.4
  • 60
    • 0032508227 scopus 로고    scopus 로고
    • Is tamoxifen effective in prevention of breast cancer?
    • Pritchard K.I. Is tamoxifen effective in prevention of breast cancer? Lancet. 352:1998;80-81.
    • (1998) Lancet , vol.352 , pp. 80-81
    • Pritchard, K.I.1
  • 62
    • 0030749427 scopus 로고    scopus 로고
    • Expression of the prolactin gene in normal and neoplastic human breast tissues and human mammary cell lines: Promoter usage and alternative mRNA splicing
    • Shaw-Bruha C.M., Pirrucello S.J., Shull J.D. Expression of the prolactin gene in normal and neoplastic human breast tissues and human mammary cell lines: promoter usage and alternative mRNA splicing. Breast Cancer Res. Treat. 44:1997;243-253.
    • (1997) Breast Cancer Res. Treat. , vol.44 , pp. 243-253
    • Shaw-Bruha, C.M.1    Pirrucello, S.J.2    Shull, J.D.3
  • 63
    • 0029035666 scopus 로고
    • Structural variants of prolactin: Occurence and physiological significance
    • Sinha Y.N. Structural variants of prolactin: occurence and physiological significance. Endocr. Rev. 16:1995;354-369.
    • (1995) Endocr. Rev. , vol.16 , pp. 354-369
    • Sinha, Y.N.1
  • 64
    • 0033573994 scopus 로고    scopus 로고
    • Opposing actions of intact and N-terminal fragments of the human prolactin/growth hormone family members on angiogenesis: Novel mechanism for the regulation of angiogenesis
    • Struman I., Bentzein F., Lee H., Mainfroid V., D'Angelo G., Goffin V., Weiner R.I., Martial J.A. Opposing actions of intact and N-terminal fragments of the human prolactin/growth hormone family members on angiogenesis: novel mechanism for the regulation of angiogenesis. Proc. Natl. Acad. Sci. USA. 96:1999;1246-1251.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 1246-1251
    • Struman, I.1    Bentzein, F.2    Lee, H.3    Mainfroid, V.4    D'Angelo, G.5    Goffin, V.6    Weiner, R.I.7    Martial, J.A.8
  • 65
    • 0014724529 scopus 로고
    • Multiple hormone interactions in the development of mammary gland in vitro
    • Topper Y.J. Multiple hormone interactions in the development of mammary gland in vitro. Recent. Prog. Horm. Res. 26:1970;287-308.
    • (1970) Recent. Prog. Horm. Res. , vol.26 , pp. 287-308
    • Topper, Y.J.1
  • 69
    • 0031851198 scopus 로고    scopus 로고
    • Prolactin: The forgotten hormone of human breast cancer
    • Vonderhaar B.K. Prolactin: the forgotten hormone of human breast cancer. Pharmacol. Ther. 79:1998;169-178.
    • (1998) Pharmacol. Ther. , vol.79 , pp. 169-178
    • Vonderhaar, B.K.1
  • 70
    • 0030050701 scopus 로고    scopus 로고
    • Binding in the growth hormone receptor complex
    • Wells J.A. Binding in the growth hormone receptor complex. Proc. Natl. Acad. Sci. USA. 93:1996;1-6.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 1-6
    • Wells, J.A.1
  • 71
    • 0031454715 scopus 로고    scopus 로고
    • Activation of the prolactin receptor but not the growth hormone receptor is important for induction of mammary tumors in transgenic mice
    • Wennbo H., Gebre-Medhin M., Gritli-Linde A., Ohlsson C., Isaksson O.G., Tornell J. Activation of the prolactin receptor but not the growth hormone receptor is important for induction of mammary tumors in transgenic mice. J. Clin. Invest. 100:1997;2744-2751.
    • (1997) J. Clin. Invest. , vol.100 , pp. 2744-2751
    • Wennbo, H.1    Gebre-Medhin, M.2    Gritli-Linde, A.3    Ohlsson, C.4    Isaksson, O.G.5    Tornell, J.6


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