Computational stabilization of human growth hormone

Protein Science

Volumn 11, Issue 6, 2002, Pages 1452-1461

  Filikov, Anton V ^a   Hayes, Robert J ^a   Luo, Peizhi ^a   Stark, Diane M ^a   Chan, Cheryl ^a   Kundu, Anirban ^a   Dahiyat, Bassil I ^a  

^a Xencor Inc   (United States)

Author keywords

Entropy; Free energy; Human growth hormone; Protein design; Thermostability

Indexed keywords

HUMAN GROWTH HORMONE; HYDROGEN; GROWTH HORMONE;

ALGORITHM; ARTICLE; CELL PROLIFERATION; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG FORMULATION; DRUG STABILITY; ELECTRICITY; ENERGY; ENTROPY; MELTING POINT; PITUITARY DWARFISM; PRIORITY JOURNAL; SHELF LIFE; SUSTAINED RELEASE PREPARATION; THERMOSTABILITY; AMINO ACID SEQUENCE; ANIMAL; CELL DIVISION; CELL LINE; CHEMISTRY; COMPUTER SIMULATION; DRUG EFFECT; GENETICS; HUMAN; MOLECULAR GENETICS; MOUSE; MUTATION; PROTEIN FOLDING;

AMINO ACID SEQUENCE; ANIMALS; CELL DIVISION; CELL LINE; COMPUTER SIMULATION; DRUG STABILITY; ELECTROSTATICS; ENTROPY; GROWTH HORMONE; HUMANS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN FOLDING;

EID: 0036116419     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.3500102     Document Type: Article

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