Aspartate 171 is the major primate-specific determinant of human growth hormone: Engineering porcine growth hormone to activate the human receptor

Journal of Biological Chemistry

Volumn 272, Issue 43, 1997, Pages 27077-27083

  Behncken, Stuart N ^a   Rowlinson, Scott W ^a,b   Rowland, Jennifer E ^a   Conway Campbell, Becky L ^a   Monks, Thea A ^a   Waters, Michael J ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ARGININE; ASPARTIC ACID; GROWTH HORMONE; GROWTH HORMONE BINDING PROTEIN; GROWTH HORMONE RECEPTOR; HISTIDINE; HUMAN GROWTH HORMONE; LEUCINE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; SPECIES DIFFERENCE;

AMINO ACID SUBSTITUTION; ANIMALS; ARGININE; ASPARTIC ACID; BINDING SITES; CELL DIVISION; CELL LINE; GROWTH HORMONE; HISTIDINE; HUMAN GROWTH HORMONE; HUMANS; KINETICS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PRIMATES; RABBITS; RECEPTORS, SOMATOTROPIN; SWINE; TRANSFECTION;

ANIMALIA; ORYCTOLAGUS CUNICULUS; PRIMATES; SUIDAE;

EID: 0030854395     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.43.27077     Document Type: Article

References (24)

1. Wells, J. A. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 1-6
2. Takahashi, Y., Kaji, H., Okimura, Y., Goji, K., Abe, H., and Chihara, K. (1996) N. Engl. J. Med. 334, 432-436
3. De Vos, A. M., Ultsch, M., and Kossiakoff, A. A. (1992) Science 255, 306-312
4. Cunningham, B. C., and Wells, J. A. (1993) J. Mol. Biol. 234, 554-563
5. Clackson, T., and Wells, J. A. (1995) Science 267, 383-386
6. Cunningham, B. C., and Wells, J. A. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 3407-3411
7. Lauterio, T. J., Trivedi, B., Kapadia, M., and Daughaday, W. H. (1988) Comp. Biochem. Physiol. 91, 15-19
8. Gobius, K. S., Rowlinson, S. W., Barnard, R., Mattick, J. S., and Waters, M. J. (1992) J. Mol. Endocrinol. 9, 213-220
9. Souza, S. C., Frick, G. P., Wang, X., Kopchick, J. J., Lobo, R. B., and Goodman, H. M. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 959-963
10. Rowlinson, S. W., Barnard, R., Bastiras, S., Robins, A. J., Senn, C., Wells, J. R. E., Brinkworth, R., and Waters, M. J. (1994) Biochemistry 33, 11724-11733
11. Rowlinson, S. W., Barnard, R., Bastiras, S., Robins, A. J., Brinkworth, R., and Waters, M. J. (1995) J. Biol. Chem. 270, 16833-16839
12. Waters, M. J., and Friesen, H. G. (1979) J. Biol. Chem. 254, 6815-6825
13. Fuh, G., Cunningham, B. C., Fukunaga, R., Nagata, S., Goeddel, D. V., and Wells, J. A. (1992) Science 256, 1677-1680
14. Cunningham, B. C., Ultsch, M., Abraham, M., DeVos, A. M., Mulkerrin, M. G., Clauser, K. R., and Wells, J. A. (1991) Science 254, 821-825
15. Nicoll, C. S., Mayer, G. L., and Russel, S. M. (1986) Endocr. Rev 7, 169-203
16. Aston, R., Holder, A. T., Preece, M. A., and Ivanyi, J. (1986) J. Endocrinol. 110, 381-388
17. Layton, M. J., Owczarek, C. M., Metcalf, D., Clark, R. L., Smith, D. K., Treutlein, H. R., and Nicola, N. A. (1994) J. Biol. Chem. 269, 29891-29896
18. Shanafelt, A. B., Johnson, K. E., and Kastelein, R. A. (1991) J. Biol. Chem. 266, 13804-13810
19. Cunningham, B. C., Jhurani, P., Ng, P., and Wells, J. A. (1989) Science 243, 1330-1336
20. Barnard, R., Rowlinson, S. W., and Waters, M. J. (1989) J. Theor. Biol. 140, 355-367
21. Staten, N. R., Byatt, J. C., and Krivi, G. G. (1993) J. Biol. Chem. 268, 18467-18473
22. Philo, J. S., Aoki, K. H., Arakawa, T., Narhi, L. O., and Wen, J. (1996) Biochemistry 35, 1681-1691
23. Rozakis-Adcock, M., and Kelly, P. A. (1992) J. Biol. Chem. 267, 7428-7433
24. Cunningham, B. C., and Wells, J. A. (1989) Science 244, 1081-1085