Crystal structure of an antagonist mutant of human growth hormone, G120R, in complex with its receptor at 2.9 Å resolution

Journal of Biological Chemistry

Volumn 271, Issue 50, 1996, Pages 32197-32203

  Sundström, Michael ^a   Lundqvist, Tomas ^a   Rödin, Joakim ^a   Giebel, Lutz B ^b   Milligan, Dan ^b   Norstedt, Gunnar ^a  

^a PFIZER INC   (United States)

^b Arris Pharmaceutical Corporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE; GROWTH HORMONE RECEPTOR;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; HORMONE STRUCTURE; HUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

CRYSTALLOGRAPHY, X-RAY; GROWTH HORMONE; HORMONE ANTAGONISTS; HUMAN GROWTH HORMONE; HUMANS; HYDROGEN BONDING; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; RECEPTORS, SOMATOTROPIN; RECOMBINANT PROTEINS;

EID: 0029770041     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.50.32197     Document Type: Article

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