Active trans-synaptic capture of membrane fragments by natural killer cells

European Journal of Immunology

Volumn 32, Issue 5, 2002, Pages 1502-1508

  Tabiasco, Julie ^a   Espinosa, Eric ^a   Hudrisier, Denis ^a   Joly, Etienne ^a   Fournié, Jean Jacques ^a   Vercellone, Alain ^a,b  

^a INSERM   (France)

^b CHU PURPAN   (France)

Author keywords

Activation; Cytoskeleton; NK cell; Signal; Synapse

Indexed keywords

ACTIN; ADENOSINE TRIPHOSPHATE; CALCIUM ION; CELL RECEPTOR; INTERLEUKIN 2; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PROTEIN KINASE C; PROTEIN TYROSINE KINASE;

ALLELE; ARTICLE; CELL FUNCTION; CELL ISOLATION; CELL LINE; CELL MEMBRANE; CONTROLLED STUDY; CYTOSKELETON; DOWN REGULATION; HUMAN; HUMAN CELL; MOLECULAR RECOGNITION; NATURAL KILLER CELL; POLYCLONAL ACTIVATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SYNAPSE; TARGET CELL;

ACTINS; CELL ADHESION; CELL LINE; CELL MEMBRANE; CYTOSKELETON; CYTOTOXICITY, IMMUNOLOGIC; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; INTERLEUKIN-2; KILLER CELLS, NATURAL; MICROSCOPY, CONFOCAL; RECEPTORS, IMMUNOLOGIC; SIGNAL TRANSDUCTION;

EID: 0036113274     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200205)32:5<1502::AID-IMMU1502>3.0.CO;2-Y     Document Type: Article

References (30)

1. The immunological synapse: A molecular machine controlling T cell activation
2. Costimulation: Building an immunological synapse
3. The immunological synapse and the actin cytoskeleton: Molecular hardware for T cell signaling
4. The immunological synapse
5. TCR-Mediated internalization of peptide-MHC complexes acquired by T cells
6. B cells extract and present immobilized antigen: Implications for affinity discrimination
7. Cutting edge: CTLs rapidly capture membrane fragments from target cells in a TCR signaling-dependent manner
8. B cells acquire antigen from target cells after synapse formation
9. Signaling pathways engaged by NK cell receptors: Double concerto for activating receptors, inhibitory receptors and NK cells
10. Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis
11. The human natural killer cell immune synapse
12. Spatial organization of signal transduction molecules in the NK cell immune synapses during MHC class I-regulated noncytolytic and cytolytic interactions
13. Characterization of a cell line, NKL, derived from an aggressive human natural killer cell leukemia
14. Latrunculins: Novel marine toxins that disrupt microfilament organization in cultured cells
15. Rottlerin is a mitochondrial uncoupler that decreases cellular ATP levels and indirectly blocks protein kinase cdelta tyrosine phosphorylation
16. Transfer and expression of three cloned human non-HLA-A,B,C class I major histocompatibility complex genes in mutant lymphoblastoid cells
17. Inhibition of selective signaling events in natural killer cells recognizing major histocompatibility complex class I
18. The immunological relay race: B cells take antigen by synapse
19. Role of the actin cytoskeleton in T cell absorption and internalization of ligands from APC
20. Environmental control of immunological synapse formation and duration
21. The Vav-Rac1 pathway in cytotoxic lymphocytes regulates the generation of cell-mediated killing
22. Role of actin in anchoring postsynaptic receptors in cultured hippocampal neurons: Differential attachment of NMDA versus AMPA receptors
23. Direct interaction in T cells between thetaPKC and the tyrosine kinase p59fyn
24. Pivotal role of phosphoinositide-3 kinase in regulation of cytotoxicity in natural killer cells
25. Engagement of natural cytotoxicity programs regulates AP-1 expression in the NKL human NK cell line
26. Functional role for Syk tyrosine kinase in natural killer cell-mediated natural cytotoxicity
27. Surface markers on human b and t lymphocytes. VI. Cytotoxicity against cell lines as a functional marker for lymphocyte subpopulations
28. Surface IgM-kappa specificity on a Burkitt lymphoma cell in vivo and in derived culture lines
29. Specificity of HLA class I antigen recognition by human NK clones: Evidence for clonal heterogeneity, protection by self and non-self alleles, and influence of the target cell type
30. Mutations that impair a posttranscriptional step in expression of HLA-A and -B antigens