Role of the actin cytoskeleton in T cell absorption and internalization of ligands from APC1

Journal of Immunology

Volumn 166, Issue 8, 2001, Pages 5099-5107

  Hwang, I ^a   Sprent, J ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CD28 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN; T LYMPHOCYTE RECEPTOR;

ABSORPTION; ACTIN FILAMENT; ANIMAL CELL; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ANTIGEN RECOGNITION; ARTICLE; INTERNALIZATION; LIGAND BINDING; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 0035871721     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.166.8.5099     Document Type: Article

References (41)

1. The immunological synapse and the actin cytoskeleton: Molecular hardware for T cell signaling
2. Three-dimensional segregation of supramolecular activation clusters in T cells
3. A receptor/cytoskeletal movement triggered by costimulation during T cell activation
4. T lymphocyte costimulation mediated by reorganization of membrane microdomains
5. CD28/B7 system of T cell co-stimulation
6. + T cells with Drosophila cell transfectants as antigen presenting cells
7. Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy
8. + T cells
9. Triggering the TCR complex causes the downregulation of nonengaged receptors by a signal transduction-dependent mechanism
10. Specific adsorption of IgM antibody onto H-2-activated mouse T lymphocytes
11. Specific binding of K- and I-region products of the H-2 complex to activated thymus-derived (T) cells belonging to different Ly subclasses
12. Cell surface appearance of unexpected host MHC determinants on thymocytes from radiation bone marrow chimeras
13. I-A antigens on cloned alloreactive murine T lymphocytes are acquired passively
14. Class II MHC/peptide complexes are released from APC and are acquired by T cell responders during specific antigen recognition
15. TCR-mediated internalization of peptide-MHC complexes acquired by T cells
16. T cells can use either TCR or CD28 receptors to absorb and internalize cell-surface molecules derived from antigen-presenting cells
17. Tolerance induction in double specific T cell receptor transgenic mice varies with antigen
18. Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells
19. Latrunculins: Novel marine toxins that disrupt microfilament organization in cultured cells
20. Latrunculins: Novel marine macrolides that disrupt microfilament organization and affect cell growth. I. Comparison with cytochalasin D
21. Differential T cell costimulatory requirements in CD28-deficient mice
22. Positive and negative selection of an antigen receptor on T cells in transgenic mice
23. B7-1 and B7-2 have overlapping, critical roles in immunoglobulin class switching and germinal center formation
24. + T cells
25. Resting and activated T cells display different requirements for CD8 molecules
26. High levels of a major histocompatibility complex II-self peptide complex on dendritic cells from the T cell areas of lymph nodes
27. 2m facilitates the folding of the α1 and α2 domains during de novo synthesis
28. Do effector and memory T helper cells also need B7 ligand costimulatory signals?
29. + mature thymocytes
30. Enhancement of LFA-1-mediated cell adhesion by triggering through CD2 or CD3 on T lymphocytes
31. T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1
32. Ins and outs of LFA-1
33. Antigen recognition by T cells activated in the mixed lymphocyte reaction: Specific binding of allogeneic cell material after removal of surface-bound antigen by trypsin
34. Specific binding of radiolabeled membrane vesicles by T cells activated in the mixed lymphocyte reaction
35. Eradication of established murine tumors using a novel cell-free vaccine: Dendritic cell-derived exosomes
36. The actin cytoskeleton is required for receptor-mediated endocytosis in mammalian cells
37. Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy: Role of T cell actin cytoskeleton
38. + T cells via signal 1 alone
39. Differential clustering of CD4 and CD3ζ during T cell recognition
40. Visualizing the dynamics of T cell activation: Intracellular adhesion molecule 1 migrates rapidly to the T cell/B cell interface and acts to sustain calcium levels
41. + T cells independently of the CD28/B7 and LFA-1/ICAM-1 costimulatory interactions