Involvement of DNA mismatch repair in folate deficiency-induced apoptosis

Journal of Nutritional Biochemistry

Volumn 13, Issue 6, 2002, Pages 355-363

  Gu, Liya ^a   Wu, Jianxin ^a   Qiu, Lu ^a   Jennings, C Darrell ^a  

^a CAPITAL INSTITUTE OF PEDIATRICS   (China)

Author keywords

Apoptosis; DNA repair; Folate deficiency

Indexed keywords

FOLIC ACID; PROTEIN; PROTEIN MUTLALPHA; PROTEIN MUTSALPHA; PROTEIN P53; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BASE PAIRING; BIOCHEMISTRY; CARCINOGENESIS; CELL DAMAGE; CELL DEATH; CELL PROTECTION; CONTROLLED STUDY; DNA DAMAGE; FOLIC ACID DEFICIENCY; HUMAN; HUMAN CELL; IN VITRO STUDY; MISMATCH REPAIR;

EID: 0036089964     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0955-2863(02)00178-X     Document Type: Article

References (47)

1. Folate deficiency beyond megaloblastic anemia: Hyperhomocysteinemia and other manifestations of dysfunctional folate status
2. A polymorphism of the methionine synthase gene: Association with plasma folate, vitamin B12, homocyst(e)ine, and colorectal cancer risk
3. Folate, colitis, dysplasia, and cancer
4. A prospective study of folate intake and the risk of breast cancer
5. Pancreatic cancer risk and nutrition-related methyl-group availability indicators in male smokers
6. Cancer prevention and diet: Help from single nucleotide polymorphisms
7. Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: Implications for cancer and neuronal damage
8. Uracil misincorporation in human DNA detected using single cell gel electrophoresis
9. DNA instability (strand breakage, uracil misincorporation, and defective repair) is increased by folic acid depletion in human lymphocytes in vitro
10. Folate, vitamin B12, homocysteine status and DNA damage in young Australian adults
11. Nutritional folate-deficiency in Chinese hamster ovary cells. Chromosomal abnormalities associated with perturbations in nucleic acid precursors
12. Folate depletion impairs DNA excision repair in the colon of the rat
13. Microsatellite instability in non-neoplastic mucosa of patients with ulcerative colitis: Effect of folate supplementation
14. Mismatch repair in replication fidelity, genetic recombination, and cancer biology
15. Mammalian DNA mismatch repair
16. Molecular mechanisms of DNA mismatch repair
17. Biochemistry and genetics of eukaryotic mismatch repair
18. DNA mismatch repair in tumor suppression
19. Isolation of an hMSH2-p160 heterodimer that restores DNA mismatch repair to tumor cells
20. GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells
21. Isolation of MutSβ from human cells and comparison of the mismatch repair specificities of MutSβ and MutSα
22. HMutSbeta, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA
23. The Saccharomyces cerevisiae MLH3 gene functions in MSH3-dependent suppression of frameshift mutations
24. Identification of a second MutL DNA mismatch repair complex (hPMS1 and hMLH1) in human epithelial cells
25. Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs
26. MLH3: A DNA mismatch repair gene associated with mammalian microsatellite instability
27. Identification of hMutLbeta, a Heterodimer of hMLH1 and hPMS1
28. Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines
29. + tumor cells
30. Human MutSα specifically binds to DNA containing aminofluorene and acetylaminofluorene adducts
31. Mismatch repair processing of carcinogen-DNA adducts triggers apoptosis
32. Folate deficiency induces a cell cycle-specific apoptosis in HepG2 cells
33. A role for p53 in DNA end rejoining by human cell extracts
34. Altered p53 status correlates with differences in sensitivity to radiation-induced mutation and apoptosis in two closely related human lymphoblast lines
35. The role of mismatch repair in DNA damage-induced apoptosis
36. Isolation and partial characterization of human cell mutants differing in sensitivity to killing and mutation by methylnitrosourea and N-methyl-N′-nitro-nitrosoguanidine
37. An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair
38. Mutations in GTBP in genetically unstable cells
39. Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N′-nitro-N- nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation [published erratum appears in Cancer Res 1995 Jan 1;55(1):201]
40. Apoptosis and proliferation under conditions of deoxynucleotide pool imbalance in liver of folate/methyl deficient rats
41. Apoptosis mediates and thymidine prevents erythroblast destruction in folate deficiency anemia
42. Apoptosis of late-stage erythroblasts in megaloblastic anemia: Association with DNA damage and macrocyte production
43. Folate and colorectal carcinogenesis: Is DNA repair the missing link?
44. The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage [In Process Citation]
45. HMutSa- and hMutLa-dependent phosphorylation of p53 in response to DNA methylator damage
46. Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents