Diabetic retinopathy and the NMDA receptor

Drug News and Perspectives

Volumn 15, Issue 4, 2002, Pages 226-232

  Smith, Sylvia B ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

CALCIUM MOBILIZATION; DIABETES MELLITUS; DIABETIC RETINOPATHY; HUMAN; NERVE CELL DEGENERATION; NERVE CELL NECROSIS; NEUROMODULATION; NONHUMAN; PATHOPHYSIOLOGY; RETINA BLOOD FLOW; RETINA GANGLION CELL; REVIEW;

EID: 0036087824     PISSN: 02140934     EISSN: None     Source Type: Journal    
DOI: 10.1358/dnp.2002.15.4.840055     Document Type: Review

References (67)

1. Diabetic retinopathy
2. Diabetic retinopathy
3. Diabetic Retinopathy
4. The Wisconsin epidemiologic study of diabetic retinopathy II. Prevalence and risk of diabetic retinopathy when age at diagnosis is less than 30 years
5. Treatment of diabetic retinopathy
6. Diabetic retinopathy: An ophthalmoscopic study with a discussion of the morphologic changes and the pathogenetic factors in this disease
7. Proliferative diabetic retinopathy: Evolution of the retinal lesions
8. Vitreous contraction in proliferative diabetic retinopathy
9. The natural course of diabetic retinopathy
10. Diabetic retinopathy
11. ABC of arterial and venous disease: Vascular complications of diabetes
12. Early loss of blue-sensitive color vision in patients with type I diabetes
13. Color vision defects in early diabetic retinopathy
14. Contrast sensitivity in diabetics with and without background retinopathy
15. Reduced contrast sensitivity may precede clinically observable retinopathy in type I diabetes
16. Comparison of oscillatory potential and pattern electroretinogram measures in diabetic retinopathy
17. Development of electroretinographic alterations in streptozotocin-induced diabetes
18. Diabetic retinopathy viewed as a neurosensory disorder
19. Excitotoxins: A possible new mechanism for the pathogenesis of ischemic retinal damage
20. Early cellular and molecular changes induced by diabetes in the retina
21. Depletion of nitric oxide synthase-containing neurons in the diabetic retina: Reversal by aminoguanidine
22. Muller's cell involvement in proliferative diabetic retinopathy
23. Müller cell changes in human diabetic retinopathy
24. Neural apoptosis in the retina during experimental and human diabetes. Early onset and effect of insulin
25. Involvement of the visual evoked potentials in type I insulin-dependent diabetes
26. Visual evoked potentials in insulin-dependent diabetics
27. Retinal nerve fiber layer defect as an early manifestation of diabetic retinopathy
28. Impaired visual evoked potential and primary axonopathy of the optic nerve in the diabetic BB/W-rat
29. Vascular and neural changes in the rat optic nerve following induction of diabetes with streptozotocin
30. Glial reactivity and impaired glutamate metabolism in short-term experimental diabetic retinopathy
31. The toxic effect of sodium L-glutamate on the inner layers of the retina
32. Glutamate-induced retinal degeneration in neonatal mice: Electron microscopy of the acutely evolving lesion
33. Ultrastructural studies on the long-term effects of sodium glutamate on the rat retina
34. The toxic effect of sodium glutamate on rat retina: Changes in putative transmitters and corresponding enzymes
35. Chronic low-dose glutamate is toxic to retinal ganglion cells: Toxicity blocked by memantine
36. Histologic changes in the inner retina of albino rats following intravitreal injection of monosodium L-glutamate
37. Molecular basis of glutamate toxicity in retinal ganglion cells
38. Retinal glutamate in diabetes and effect of antioxidants
39. Elevated gamma-aminobutyric acid, glutamate, and vascular endothelial growth factor levels in the vitreous of patients with proliferative diabetic retinopathy
40. D-serine, an endogenous synaptic modulator: Localization to astrocytes and glutamate-stimulated release
41. Developmental change of endogenous glutamate and gamma-glutamyl transferase in cultured cerebral cortical interneurons and cerebellar granule cells, and in mouse cerebral cortex and cerebellum in vivo
42. The glial cell glutamate uptake carrier countertransports pH-changing anions
43. Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis
44. Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance
45. Depression of retinal glutamate transporter function leads to elevated intravitreal glutamate levels and ganglion cell death
46. Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex
47. Localization of the glutamate transporter GLT-1 in rat and macaque monkey retinae
48. Differential expression of three glutamate transporter subtypes in the rat retina
49. Developmental expression of excitatory amino acid transporter 5: A photoreceptor and bipolar cell glutamate transporter in rat retina
50. Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate
51. Peroxynitrite inhibits glutamate transporter subtypes
52. Gases as biological messengers: Nitric oxide and carbon monoxide in the brain
53. Nitric oxide and synaptic function
54. Nitric oxide in inflammation and immune responses
55. 2+ homeostasis
56. Caspasemediated apoptosis in neuronal excitotoxicity triggered by nitric oxide
57. Involvement of nitric oxide in development of tail-tremor induced by repeated nicotine administration in rats
58. Cytoskeletal breakdown and apoptosis elicited by NO donors in cerebellar granule cells require NMDA receptor activation
59. NMDA receptor activation induces glutamate release through nitric oxide synthesis in guinea pig dentate gyrus
60. Dual actions of nitric oxide in N-methyl-Daspartate receptor-mediated neurotoxicity in cultured retinal neurons
61. Role of EDRF (nitric oxide) in diabetic renal hyperfiltration
62. Role of endothelium-derived nitric oxide in the pathogenesis of renal hemodynamic changes of experimental diabetes
63. Nitric oxide and ocular blood flow in patients with IDDM
64. Defective homocysteine metabolism as a risk factor for diabetic retinopathy
65. Moderate hyperhomocysteinaemia and retinopathy in insulin-dependent diabetes
66. Involvement of N-methyl-D-aspartate receptor and free radical in homocysteine-mediated toxicity on rat cerebellar granule cells in culture
67. Apoptotic retinal ganglion cell death is induced in vivo by the excitatory amino acid homocysteine