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Journal of Pharmacology and Experimental Therapeutics

Volumn 302, Issue 1, 2002, Pages 43-49

Effect of albumin and cytosol on enzyme kinetics of tolbutamide hydroxylation and on inhibition of CYP2C9 by gemfibrozil in human liver microsomes

(4) Wang, Jun Sheng a Wen, Xia a Backman, Janne T a Neuvonen, Pertti J a

a UNIVERSITY OF HELSINKI (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 2C9; GEMFIBROZIL; HUMAN SERUM ALBUMIN; HYDROXYTOLBUTAMIDE; TOLBUTAMIDE;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; DRUG CLEARANCE; DRUG HYDROXYLATION; ENZYME INHIBITION; ENZYME KINETICS; FEMALE; HUMAN; HUMAN TISSUE; IN VIVO STUDY; LIVER CLEARANCE; LIVER MICROSOME; MALE; PRIORITY JOURNAL;

ALBUMINS; ALGORITHMS; ANTILIPEMIC AGENTS; ARYL HYDROCARBON HYDROXYLASES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 ENZYME SYSTEM; CYTOSOL; ENZYME INHIBITORS; GEMFIBROZIL; HUMANS; HYDROXYLATION; HYPOGLYCEMIC AGENTS; KINETICS; MICROSOMES, LIVER; STEROID 16-ALPHA-HYDROXYLASE; STEROID HYDROXYLASES; TOLBUTAMIDE;

EID: 0036085348 PISSN: 00223565 EISSN: None Source Type: Journal
DOI: 10.1124/jpet.302.1.43 Document Type: Article

Times cited : (19)

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