Optimizing drug development: Strategies to assess drug metabolism/transporter interaction potential - Towards a consensus

British Journal of Clinical Pharmacology

Volumn 52, Issue 1, 2001, Pages 107-117

  Tucker, Geoffrey T ^a   Houston, J Brian ^b   Huang, Shiew Mei ^c  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETANILIDE; ASTEMIZOLE; BUFURALOL; CAFFEINE; CHLORZOXAZONE; CISAPRIDE; COUMARIN; CYTOCHROME; CYTOCHROME P450 1A2; CYTOCHROME P450 2A6; CYTOCHROME P450 2B6; CYTOCHROME P450 2C19; CYTOCHROME P450 2C8; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 2E1; CYTOCHROME P450 3A4; DEXTROMETHORPHAN; ENZYME INHIBITOR; ETHOXYRESORUFIN; FURAFYLLINE; MIBEFRADIL; MIDAZOLAM; PACLITAXEL; PHENACETIN; SORIVUDINE; TERFENADINE; TESTOSTERONE; THEOPHYLLINE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ACCURACY; CONFERENCE PAPER; CONTROLLED STUDY; DRUG APPROVAL; DRUG CONCENTRATION; DRUG METABOLISM; DRUG TRANSPORT; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INDUCTION; ENZYME INHIBITION; ENZYME SUBSTRATE; FOOD AND DRUG ADMINISTRATION; HUMAN; HUMAN CELL; HUMAN TISSUE; LAW SUIT; LIVER CELL; MICROSOME; ORGANIZATION; PHENOTYPE; PRESCRIPTION; PRIORITY JOURNAL; REGULATORY MECHANISM; STANDARDIZATION;

ALGORITHMS; BIOLOGICAL TRANSPORT; CYTOCHROME P-450 ENZYME SYSTEM; DRUG DESIGN; DRUG INTERACTIONS; HUMANS; LIVER; PHARMACEUTICAL PREPARATIONS; SWITZERLAND;

EID: 0034824312     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0306-5251.2001.Temp.1441.x     Document Type: Conference Paper

References (0)