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Current Pharmaceutical Design

Volumn 8, Issue 15, 2002, Pages 1391-1403

Beta-glucuronidase-mediated drug release

(5) de Graaf, Michelle a Boven, Epie a Scheeren, Hans W a Haisma, Hidde J a Pinedo, Herbert M a

a UNIVERSITY OF GRONINGEN (Netherlands)

Author keywords

glucuronidase prodrugs; Gene therapy; Molecular chemotherapy; Suicide genes

Indexed keywords

ANILINE MUSTARD DERIVATIVE; ANTHRACYCLINE DERIVATIVE; ANTIBODY CONJUGATE; ANTINEOPLASTIC AGENT; BETA GLUCURONIDASE; CAMPTOTHECIN DERIVATIVE; DAUNORUBICIN; DOXORUBICIN; EPIRUBICIN; FLUOROURACIL; GLUCURONIDE; IMMUNOLIPOSOME; N (4 BETA GLUCURONYL 3 NITROBENZYLOXYCARBONYL)DOXORUBICIN; PACLITAXEL; PRODRUG; CANCER ANTIBODY;

ANTIBODY DIRECTED ENZYME PRODRUG THERAPY; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CELL PERMEABILIZATION; DRUG ACTIVATION; DRUG CLEARANCE; DRUG EFFICACY; DRUG GLUCURONIDATION; DRUG HALF LIFE; DRUG RELEASE; DRUG SAFETY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; DRUG UPTAKE; EXPERIMENTAL MODEL; GENE THERAPY; GENETIC CODE; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; HYDROPHILICITY; MONOTHERAPY; MOUSE; NONHUMAN; OVARY CANCER; PRIORITY JOURNAL; TUMOR CELL; TUMOR NECROSIS; ANIMAL; BIOSYNTHESIS; CHEMISTRY; ENZYME INDUCTION; GENETICS; IMMUNOLOGY; METABOLISM; NEOPLASM; REVIEW;

ANIMAL; ANTIBODIES, NEOPLASM; ANTINEOPLASTIC AGENTS; ENZYME INDUCTION; GLUCURONIDASE; GLUCURONIDES; HUMAN; MICE; NEOPLASMS; PRODRUGS; ANIMALS; HUMANS;

EID: 0036015566 PISSN: 13816128 EISSN: None Source Type: Journal
DOI: 10.2174/1381612023394485 Document Type: Article

Times cited : (144)

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