Improved characteristics of a human β-glucuronidase-antibody conjugate after deglycosylation for use in antibody-directed enzyme prodrug therapy

Bioconjugate Chemistry

Volumn 7, Issue 5, 1996, Pages 606-611

  Houba, Pieter H J ^a   Boven, Epie ^a   Haisma, Hidde J ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; ENZYME ACTIVITY; MAMMALS; MONOCLONAL ANTIBODIES; PLANTS (BOTANY); SODIUM BOROHYDRIDE;

ACTIVE DRUGS; ANTIBODY CONJUGATE; ANTIBODY-DIRECTED ENZYME PRODRUG THERAPIES; DEGLYCOSYLATION; GLUCURONIDASE; GLYCANS; IMMUNOGENICITY; PRODRUG ACTIVATION; PRODRUGS; TUMOR SITE;

TUMORS;

ANIMALIA; MUS MUSCULUS;

EID: 0030250635     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc960055j     Document Type: Article

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