Oral DNA vaccination with a plasmid encoding soluble ICAM-1 modulates cytokine expression profiles in nonobese diabetic mice

Journal of Molecular Medicine

Volumn 80, Issue 5, 2002, Pages 301-308

  Van Den Engel, Natasja K ^a   An Haack, Melanie ^a   Martin, Stephan ^a   Kolb, Hubert ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Adhesion molecule; DNA immunization; NOD mouse; Plasmid; Th1 Th2; Type 1 diabetes

Indexed keywords

CYCLOPHOSPHAMIDE; CYTOKINE; DNA VACCINE; GAMMA INTERFERON; IMMUNOMODULATING AGENT; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 12P40; MESSENGER RNA; PLASMID DNA; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ACTIVITY; CELL INFILTRATION; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE PREDISPOSITION; DRUG MECHANISM; FEMALE; GENDER; HISTOLOGY; IMMUNITY; INFLAMMATION; LEUKOCYTE MIGRATION; LYMPHOCYTE; MESENTERY LYMPH NODE; MOUSE; MOUSE STRAIN; NONHUMAN; OBESITY; PANCREAS; PANCREAS ISLET; PEYER PATCH; PLASMID; PROTEIN DETERMINATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; SMALL INTESTINE; TH1 CELL; VACCINATION; ANIMAL; GENETICS; IMMUNOLOGY; INSULIN DEPENDENT DIABETES MELLITUS; NONOBESE DIABETIC MOUSE; ORAL DRUG ADMINISTRATION;

ADMINISTRATION, ORAL; ANIMAL; CYTOKINES; DIABETES MELLITUS, INSULIN-DEPENDENT; FEMALE; INTERCELLULAR ADHESION MOLECULE-1; ISLETS OF LANGERHANS; MICE; MICE, INBRED NOD; PLASMIDS; SUPPORT, NON-U.S. GOV'T; VACCINES, DNA; ANIMALS; DIABETES MELLITUS, TYPE 1;

EID: 0036012798     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00109-002-0324-8     Document Type: Article

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