메뉴 건너뛰기




Volumn 13, Issue 4, 1999, Pages 383-392

Acceleration of autoimmune diabetes by cyclophosphamide is associated with an enhanced IFN-γ secretion pathway

Author keywords

Autoimmune diabetes; Cyclophosphamide; Interferon gamma

Indexed keywords

ALPHA INTERFERON; CYCLOPHOSPHAMIDE;

EID: 0033376438     PISSN: 08968411     EISSN: None     Source Type: Journal    
DOI: 10.1006/jaut.1999.0331     Document Type: Article
Times cited : (41)

References (48)
  • 1
    • 0343690172 scopus 로고
    • Antineoplastic agents and immunosuppressants
    • London: The Pharmaceutical Press
    • Reinolds J.E.F. Antineoplastic agents and immunosuppressants. Martindale. The Extra Pharmacopoeia. 1993;The Pharmaceutical Press, London.
    • (1993) Martindale. the Extra Pharmacopoeia
    • Reinolds, J.E.F.1
  • 2
    • 0024584845 scopus 로고
    • Long-lasting skin allograft tolerance in adult mice induced across fully allogeneic (multimajor H-2 plus multiminor histocompatibility) antigen barrier by a tolerance- inducing method using cyclophosphamide
    • Mayumi H., Good R.A. Long-lasting skin allograft tolerance in adult mice induced across fully allogeneic (multimajor H-2 plus multiminor histocompatibility) antigen barrier by a tolerance- inducing method using cyclophosphamide. J. Exp. Med. 169:1989;213-238.
    • (1989) J. Exp. Med. , vol.169 , pp. 213-238
    • Mayumi, H.1    Good, R.A.2
  • 3
    • 0022473607 scopus 로고
    • A new approach to the adoptive immunotherapy of cancer with tumor-infiltrating lymphocytes
    • Rosenberg S.A., Spiess P., Lafreniere R. A new approach to the adoptive immunotherapy of cancer with tumor-infiltrating lymphocytes. Science. 233:1986;1318-1321.
    • (1986) Science , vol.233 , pp. 1318-1321
    • Rosenberg, S.A.1    Spiess, P.2    Lafreniere, R.3
  • 4
    • 0020061501 scopus 로고
    • Immunological responses to fed protein antigens in mice. I. Reversal of oral tolerance to ovalbumine by cyclophosphamide
    • Mowat A.M., Strobel S., Drummond H.E., Ferguson A. Immunological responses to fed protein antigens in mice. I. Reversal of oral tolerance to ovalbumine by cyclophosphamide. Immunology. 45:1982;105-113.
    • (1982) Immunology , vol.45 , pp. 105-113
    • Mowat, A.M.1    Strobel, S.2    Drummond, H.E.3    Ferguson, A.4
  • 5
    • 0027160041 scopus 로고
    • Cell-mediated transfer of collagen-induced arthritis in mice and its application to the analysis of the inhibitory effects of interferon-gamma and cyclophosphamide
    • Nakajima H., Hiyama Y., Takamori H., Tsukada W. Cell-mediated transfer of collagen-induced arthritis in mice and its application to the analysis of the inhibitory effects of interferon-gamma and cyclophosphamide. Clin. Exp. Immunol. 92:1993;328-335.
    • (1993) Clin. Exp. Immunol. , vol.92 , pp. 328-335
    • Nakajima, H.1    Hiyama, Y.2    Takamori, H.3    Tsukada, W.4
  • 6
    • 0018715997 scopus 로고
    • Effect of cyclophosphamide on suppressor cell activity in mice unresponsive to EAE
    • Lando Z., Teitelbaum D., Arnon R. Effect of cyclophosphamide on suppressor cell activity in mice unresponsive to EAE. J. Immunol. 123:1979;2156-2160.
    • (1979) J. Immunol. , vol.123 , pp. 2156-2160
    • Lando, Z.1    Teitelbaum, D.2    Arnon, R.3
  • 7
    • 0021716386 scopus 로고
    • Promotion of spontaneous diabetes in non-obese diabetes-prone mice by cyclophosphamide
    • Harada M., Makino S. Promotion of spontaneous diabetes in non-obese diabetes-prone mice by cyclophosphamide. Diabetologia. 27:1984;604-606.
    • (1984) Diabetologia , vol.27 , pp. 604-606
    • Harada, M.1    Makino, S.2
  • 8
    • 0023894971 scopus 로고
    • Anti-suppressor effect of cyclophosphamide on the development of spontaneous diabetes in NOD mice
    • Yasunami R., Bach J.-F. Anti-suppressor effect of cyclophosphamide on the development of spontaneous diabetes in NOD mice. Eur. J. Immunol. 18:1988;481-484.
    • (1988) Eur. J. Immunol. , vol.18 , pp. 481-484
    • Yasunami, R.1    Bach, J.-F.2
  • 10
    • 0028354067 scopus 로고
    • Immunoregulatory and cytokine imbalances in the pathogenesis of IDDM. Therapeutic intervention by immunostimulation
    • Rabinovitch R. Immunoregulatory and cytokine imbalances in the pathogenesis of IDDM. Therapeutic intervention by immunostimulation. Diabetes. 43:1994;613-621.
    • (1994) Diabetes , vol.43 , pp. 613-621
    • Rabinovitch, R.1
  • 11
    • 0031423760 scopus 로고    scopus 로고
    • The nonobese diabetic mouse as a model of autoimmune diabetes: Immune disregulation gets the NOD
    • Delovitch T.L., Singh B. The nonobese diabetic mouse as a model of autoimmune diabetes: Immune disregulation gets the NOD. Immunity. 7:1997;727-738.
    • (1997) Immunity , vol.7 , pp. 727-738
    • Delovitch, T.L.1    Singh, B.2
  • 12
    • 0025981388 scopus 로고
    • Essential role of interferon-γ And interleukin-6 in autoimmune insulin-dependent diabetes in NOD/Wehi mice
    • Campbell I.L., Kay T.W.H., Oxbrow L., Harrison L. Essential role of interferon-γ and interleukin-6 in autoimmune insulin-dependent diabetes in NOD/Wehi mice. J. Clin. Invest. 87:1991;739-742.
    • (1991) J. Clin. Invest. , vol.87 , pp. 739-742
    • Campbell, I.L.1    Kay, T.W.H.2    Oxbrow, L.3    Harrison, L.4
  • 13
    • 0031913650 scopus 로고    scopus 로고
    • Islet T cells secreting IFN-γ In NOD mouse diabetes: Arrest by p277 peptide treatment
    • Ablamunits V., Elias D., Reshef T., Cohen I.R. Islet T cells secreting IFN-γ in NOD mouse diabetes: arrest by p277 peptide treatment. J. Autoimmun. 11:1998;73-81.
    • (1998) J. Autoimmun. , vol.11 , pp. 73-81
    • Ablamunits, V.1    Elias, D.2    Reshef, T.3    Cohen, I.R.4
  • 14
    • 0032940596 scopus 로고    scopus 로고
    • The pathogenicity of islet-infiltrating lymphocytes in the non-obese diabetic (NOD) mouse
    • Ablamunits V., Elias D., Cohen I.R. The pathogenicity of islet-infiltrating lymphocytes in the non-obese diabetic (NOD) mouse. Clin. Exp. Immunol. 115:1999;260-267.
    • (1999) Clin. Exp. Immunol. , vol.115 , pp. 260-267
    • Ablamunits, V.1    Elias, D.2    Cohen, I.R.3
  • 15
    • 0017179001 scopus 로고
    • Streptozotocin-induced pancreatic insulitis: New model of diabetes mellitus
    • Like A.A., Rossini A.A. Streptozotocin-induced pancreatic insulitis: new model of diabetes mellitus. Science. 193:1976;415-417.
    • (1976) Science , vol.193 , pp. 415-417
    • Like, A.A.1    Rossini, A.A.2
  • 16
    • 0027953701 scopus 로고
    • Autoimmune diabetes induced by the β-cell toxin STZ. Immunity to the 60-kDa heat shock protein and to insulin
    • Elias D., Prigozhin H., Polak N., Rapaport M., Lohze A.W., Cohen I.R. Autoimmune diabetes induced by the β-cell toxin STZ. Immunity to the 60-kDa heat shock protein and to insulin. Diabetes. 43:1994;992-998.
    • (1994) Diabetes , vol.43 , pp. 992-998
    • Elias, D.1    Prigozhin, H.2    Polak, N.3    Rapaport, M.4    Lohze, A.W.5    Cohen, I.R.6
  • 17
    • 0026322837 scopus 로고
    • Vaccination against autoimmune mouse diabetes with a T-cell epitope of the human 65 kDa heat shock protein
    • Elias D., Reshef T., Birk O.S., van der Zee R., Walker M.D., Cohen I.R. Vaccination against autoimmune mouse diabetes with a T-cell epitope of the human 65 kDa heat shock protein. Proc. Natl. Acad. Sci. U S A. 88:1991;3088-3091.
    • (1991) Proc. Natl. Acad. Sci. U S a , vol.88 , pp. 3088-3091
    • Elias, D.1    Reshef, T.2    Birk, O.S.3    Van Der Zee, R.4    Walker, M.D.5    Cohen, I.R.6
  • 18
    • 0027263751 scopus 로고
    • A simple, sensitive, dual mAb based ELISA for murine gamma interferon determination: Comparison with common bioassays
    • Yang X., Hayglass K. A simple, sensitive, dual mAb based ELISA for murine gamma interferon determination: comparison with common bioassays. J. Immunoassays. 14:1993;129-148.
    • (1993) J. Immunoassays , vol.14 , pp. 129-148
    • Yang, X.1    Hayglass, K.2
  • 19
    • 0022633155 scopus 로고
    • The ELISA-plaque assay for the detection and enumeration of antibody-secreting cells
    • Sedgwick J.D., Holt P.G. The ELISA-plaque assay for the detection and enumeration of antibody-secreting cells. J. Immunol. Meth. 87:1986;37-44.
    • (1986) J. Immunol. Meth. , vol.87 , pp. 37-44
    • Sedgwick, J.D.1    Holt, P.G.2
  • 20
    • 0028055003 scopus 로고
    • Multiple low-dose streptozotocin-induced diabetes in NOD-scid/scid mice in the absence of functional lymphocytes
    • Gerling I.C., Friedman H., Greiner D.L., Shultz L.D., Leiter E.H. Multiple low-dose streptozotocin-induced diabetes in NOD-scid/scid mice in the absence of functional lymphocytes. Diabetes. 43:1994;433-440.
    • (1994) Diabetes , vol.43 , pp. 433-440
    • Gerling, I.C.1    Friedman, H.2    Greiner, D.L.3    Shultz, L.D.4    Leiter, E.H.5
  • 21
    • 0024563945 scopus 로고
    • Cyclophosphamide-induced diabetes in NOD/WEHI mice. Evidence for suppression in spontaneous autoimmune diabetes mellitus
    • Charlton B., Bacekj A., Slattery R.M., Mandel T. Cyclophosphamide-induced diabetes in NOD/WEHI mice. Evidence for suppression in spontaneous autoimmune diabetes mellitus. Diabetes. 38:1989;441-447.
    • (1989) Diabetes , vol.38 , pp. 441-447
    • Charlton, B.1    Bacekj, A.2    Slattery, R.M.3    Mandel, T.4
  • 22
    • 0024500755 scopus 로고
    • T cell mediated inhibition of the transfer of autoimmune diabetes in NOD mice
    • Boitard C., Yasunami R., Dardenne M., Bach J.-F. T cell mediated inhibition of the transfer of autoimmune diabetes in NOD mice. J. Exp. Med. 169:1989;1669-1680.
    • (1989) J. Exp. Med. , vol.169 , pp. 1669-1680
    • Boitard, C.1    Yasunami, R.2    Dardenne, M.3    Bach, J.-F.4
  • 23
    • 0025115596 scopus 로고
    • The transfer of autoimmune diabetes in NOD mice can be inhibited or accelerated by distinct cell populations present in normal splenocytes taken from young males
    • Hutchins P.R., Cooke A. The transfer of autoimmune diabetes in NOD mice can be inhibited or accelerated by distinct cell populations present in normal splenocytes taken from young males. J. Autoimmun. 3:1990;175-185.
    • (1990) J. Autoimmun. , vol.3 , pp. 175-185
    • Hutchins, P.R.1    Cooke, A.2
  • 24
    • 0030022742 scopus 로고    scopus 로고
    • Transfer of diabetes in the NOD- scid mouse by CD4 T-cell clones
    • Peterson J.D., Haskins K. Transfer of diabetes in the NOD- scid mouse by CD4 T-cell clones. Diabetes. 45:1996;328-336.
    • (1996) Diabetes , vol.45 , pp. 328-336
    • Peterson, J.D.1    Haskins, K.2
  • 26
    • 0027468997 scopus 로고
    • Adoptive transfer of diabetes into immunodeficient NOD-scid/scid mice. Relative contributions of CD4+and CD8+T-cells from diabetic versus pre-diabetic NOD.NON-Thy-1a donors
    • Christianson S.W., Shulz L.D., Leiter E.H. Adoptive transfer of diabetes into immunodeficient NOD-scid/scid mice. Relative contributions of CD4+and CD8+T-cells from diabetic versus pre-diabetic NOD.NON-Thy-1a donors. Diabetes. 42:1993;44-55.
    • (1993) Diabetes , vol.42 , pp. 44-55
    • Christianson, S.W.1    Shulz, L.D.2    Leiter, E.H.3
  • 27
    • 0022640843 scopus 로고
    • Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
    • Mosmann T.R., Cherwinski H., Bond M.W., Giedlin M.A., Coffman R.L. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J. Immunol. 136:1986;2348-2357.
    • (1986) J. Immunol. , vol.136 , pp. 2348-2357
    • Mosmann, T.R.1    Cherwinski, H.2    Bond, M.W.3    Giedlin, M.A.4    Coffman, R.L.5
  • 28
    • 0029773865 scopus 로고    scopus 로고
    • Diabetogenic T-cell clones
    • Haskins K., Wegmann D. Diabetogenic T-cell clones. Diabetes. 45:1996;1299-1305.
    • (1996) Diabetes , vol.45 , pp. 1299-1305
    • Haskins, K.1    Wegmann, D.2
  • 29
    • 0027291701 scopus 로고
    • Altered cytokine activity in adjuvant inhibition of autoimmune diabetes
    • Shehadeh N.N., LaRosa F., Lafferty K.J. Altered cytokine activity in adjuvant inhibition of autoimmune diabetes. J. Autoimmun. 6:1993;291-300.
    • (1993) J. Autoimmun. , vol.6 , pp. 291-300
    • Shehadeh, N.N.1    Larosa, F.2    Lafferty, K.J.3
  • 31
    • 0028882673 scopus 로고
    • Suppression of insulitis in NOD mice by oral insulin administration ia associated with selective expression of IL-4, IL-10, TGF-β And prostaglandin-E
    • Hancock W.W., Polanski M., Zhang J., Blogg N., Weiner H.L. Suppression of insulitis in NOD mice by oral insulin administration ia associated with selective expression of IL-4, IL-10, TGF-β and prostaglandin-E. Am. J. Pathol. 147:1995;1193-1199.
    • (1995) Am. J. Pathol. , vol.147 , pp. 1193-1199
    • Hancock, W.W.1    Polanski, M.2    Zhang, J.3    Blogg, N.4    Weiner, H.L.5
  • 33
    • 0029838995 scopus 로고    scopus 로고
    • Pancreatic expression of interleukin-4 abrogates insulitis and autoimmune diabetes in nonobese diabetic mice
    • Mueller R., Krahl T., Sarvetnick N. Pancreatic expression of interleukin-4 abrogates insulitis and autoimmune diabetes in nonobese diabetic mice. J. Exp. Med. 186:1996;1093-1099.
    • (1996) J. Exp. Med. , vol.186 , pp. 1093-1099
    • Mueller, R.1    Krahl, T.2    Sarvetnick, N.3
  • 35
    • 0030960632 scopus 로고    scopus 로고
    • Hsp60 peptide therapy of NOD mouse diabetes induces a Th2 cytokine burst and downregulates autoimmunity to various β-cell antigens
    • Elias D., Meilin A., Ablamunits V., Birk O.S., Carmi P., Könen-Waisman S., Cohen I.R. Hsp60 peptide therapy of NOD mouse diabetes induces a Th2 cytokine burst and downregulates autoimmunity to various β-cell antigens. Diabetes. 46:1997;758-764.
    • (1997) Diabetes , vol.46 , pp. 758-764
    • Elias, D.1    Meilin, A.2    Ablamunits, V.3    Birk, O.S.4    Carmi, P.5    Könen-Waisman, S.6    Cohen, I.R.7
  • 36
    • 0020024396 scopus 로고
    • Multiple low-dose streptozotocin-induced hyperglycemia and insulitis in C57BL mice: Influence of inbred background, sex, and thymus
    • Leiter E.H. Multiple low-dose streptozotocin-induced hyperglycemia and insulitis in C57BL mice: Influence of inbred background, sex, and thymus. Proc. Natl. Acad. Sci. U S A. 79:1982;630-634.
    • (1982) Proc. Natl. Acad. Sci. U S a , vol.79 , pp. 630-634
    • Leiter, E.H.1
  • 39
    • 0018074445 scopus 로고
    • Sex differences in the multiple-dose streptozo- tocin model of diabetes
    • Rossini A.A., Williams R.M., Appel M.C., Like A.A. Sex differences in the multiple-dose streptozo- tocin model of diabetes. Endocrinology. 108:1978;1518-1520.
    • (1978) Endocrinology , vol.108 , pp. 1518-1520
    • Rossini, A.A.1    Williams, R.M.2    Appel, M.C.3    Like, A.A.4
  • 40
    • 0031045622 scopus 로고    scopus 로고
    • Origin, maturation and antigen-presenting function of dendritic cells
    • Cella M., Salusto F., Lanzavecchia A. Origin, maturation and antigen-presenting function of dendritic cells. Curr. Opin. Immunol. 9:1997;10-16.
    • (1997) Curr. Opin. Immunol. , vol.9 , pp. 10-16
    • Cella, M.1    Salusto, F.2    Lanzavecchia, A.3
  • 41
    • 0032189552 scopus 로고    scopus 로고
    • The evolution of self-tolerance: A new cell arises to meet the challenge of self-reactivity
    • de StGroth B.F. The evolution of self-tolerance: a new cell arises to meet the challenge of self-reactivity. Immunol. Today. 19:1998;448-454.
    • (1998) Immunol. Today , vol.19 , pp. 448-454
    • De Stgroth, B.F.1
  • 42
    • 0030963614 scopus 로고    scopus 로고
    • Induction of Th1 and Th2 CD4+T cell responses: The alternative approaches
    • Constant S.L., Bottomly K. Induction of Th1 and Th2 CD4+T cell responses: The alternative approaches. Annu. Rev. Immunol. 15:1997;297-322.
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 297-322
    • Constant, S.L.1    Bottomly, K.2
  • 43
    • 0030032393 scopus 로고    scopus 로고
    • Interleukin-12 gene expression is associated with rapid development of diabetes mellitus in non-obese diabetic mice
    • Rothe H., Burkart V., Faust A., Kolb H. Interleukin-12 gene expression is associated with rapid development of diabetes mellitus in non-obese diabetic mice. Diabetologia. 39:1996;119-122.
    • (1996) Diabetologia , vol.39 , pp. 119-122
    • Rothe, H.1    Burkart, V.2    Faust, A.3    Kolb, H.4
  • 44
    • 0002484711 scopus 로고    scopus 로고
    • Spontaneous insulin-dependent diabetes mellitus (IDDM) in nonobese diabetic (NOD) mice: Comparisons with experimentally induced IDDM
    • J.H. McNeil. Boca Raton: CRC Press LLC
    • Leiter E.H., Gerling I.C., Flynn J.C. Spontaneous insulin-dependent diabetes mellitus (IDDM) in nonobese diabetic (NOD) mice: Comparisons with experimentally induced IDDM. McNeil J.H. Experimental models of diabetes. 1999;CRC Press LLC, Boca Raton.
    • (1999) Experimental Models of Diabetes
    • Leiter, E.H.1    Gerling, I.C.2    Flynn, J.C.3
  • 45
    • 0021162631 scopus 로고
    • Immunologic studies on the induction of diabetes in experimental animals. Cellular basis for the induction of diabetes by streptozotocin
    • Kim Y.T., Steinberg C. Immunologic studies on the induction of diabetes in experimental animals. Cellular basis for the induction of diabetes by streptozotocin. Diabetes. 33:1984;771-777.
    • (1984) Diabetes , vol.33 , pp. 771-777
    • Kim, Y.T.1    Steinberg, C.2
  • 47
    • 0021873134 scopus 로고
    • Recurrent diabetes mellitus in the pancreas iso- And allograft. A light and electron microscopic and immunohistochemical analysis of four cases
    • Sibley R.K., Sutherland D.E., Goets F., Michael A.F. Recurrent diabetes mellitus in the pancreas iso- and allograft. A light and electron microscopic and immunohistochemical analysis of four cases. Lab. Invest. 53:1985;132-144.
    • (1985) Lab. Invest. , vol.53 , pp. 132-144
    • Sibley, R.K.1    Sutherland, D.E.2    Goets, F.3    Michael, A.F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.