Amiloride blockades lipopolysaccharide-induced proinflammatory cytokine biosynthesis in an IκB-α/NF-κB-dependent mechanism: Evidence for the amplification of an antiinflammatory pathway in the alveolar epithelium

American Journal of Respiratory Cell and Molecular Biology

Volumn 26, Issue 1, 2002, Pages 114-126

  Haddad, J J ^a   Land, S C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 (N,N HEXAMETHYLENE)AMILORIDE; 5-(N,N-HEXAMETHYLENE)AMILORIDE; AMILORIDE; ANTINEOPLASTIC AGENT; CYTOKINE; DIURETIC AGENT; DNA BINDING PROTEIN; DNA BINDING PROTEINS; DRUG DERIVATIVE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; RECOMBINANT PROTEIN; TUMOR NECROSIS FACTOR;

ACTIVE TRANSPORT; ANIMAL; ARTICLE; BIOLOGICAL MODEL; BIOSYNTHESIS; CELL CULTURE; CYTOLOGY; DOSE RESPONSE; DOWN REGULATION; EMBRYOLOGY; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; GENE EXPRESSION REGULATION; IMMUNOLOGY; LUNG; METABOLISM; PHOSPHORYLATION; PROMOTER REGION; RAT; SIGNAL TRANSDUCTION; TIME; UPREGULATION;

ACTIVE TRANSPORT, CELL NUCLEUS; AMILORIDE; ANIMAL; ANTINEOPLASTIC AGENTS; CELLS, CULTURED; CYTOKINES; DIURETICS; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; INTERLEUKIN-1; INTERLEUKIN-10; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; LUNG; MODELS, BIOLOGICAL; NF-KAPPA B; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); RATS; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; SUPPORT, NON-U.S. GOV'T; TIME FACTORS; TUMOR NECROSIS FACTOR; UP-REGULATION;

EID: 0036006805     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.26.1.4657     Document Type: Article

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