Two novel assays for the detection of haemin-binding properties of antimalarials evaluated with compounds isolated from medicinal plants

Journal of Antimicrobial Chemotherapy

Volumn 50, Issue 1, 2002, Pages 25-31

  Steele, J C P ^a,b   Phelps, R J ^a   Simmonds, M S J ^b   Warhurst, D C ^a   Meyer, D J ^a  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^b ROYAL BOTANIC GARDENS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ABUTA GRANDIFOLIA EXTRACT; ABUTA RUFESCENS EXTRACT; AMODIAQUINE; ANTIMALARIAL AGENT; ASPIDOSPERMA EXTRACT; BENFLUMETOL; CHLOROQUINE; CINCHONINE; CISSAMPELOS EXTRACT; DOPACHROME TAUTOMERASE; GLUTATHIONE; GRISSOSPERMUM EXTRACT; HALOFANTRINE; HEMIN; ISOQUINOLINE DERIVATIVE; MEFLOQUINE; MEPACRINE; MIGRATION INHIBITION FACTOR; MYRCIARIA EXTRACT; NATURAL PRODUCT; PLANT EXTRACT; PLECTRANTHUS EXTRACT; PRIMAQUINE; PROCATEROL; QUINIDINE; QUININE; QUINOLINE DERIVATIVE; SIMAROUBA EXTRACT; UNCLASSIFIED DRUG; UNINDEXED DRUG; ZANTHOXYLUM EXTRACT; MACROPHAGE MIGRATION INHIBITION FACTOR;

ABUTA GRANDIFOLIA; ABUTA RUFESCENS; ANTIPROTOZOAL ACTIVITY; ARTICLE; ASPIDOSPERMA; BINDING AFFINITY; CISSAMPELOS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; DATA ANALYSIS; DRUG BINDING; DRUG ISOLATION; GRISSOSPERMUM; IC 50; IN VITRO STUDY; INTERMETHOD COMPARISON; MACROPHAGE; MYRCIARIA; PLANT; PLASMODIUM FALCIPARUM; PLECTRANTHUS; PROTEIN INTERACTION; SCREENING TEST; SENSITIVITY AND SPECIFICITY; SIMAROUBACEAE; SOUTH AMERICA; TROPHOZOITE; ZANTHOXYLUM; ANIMAL; CHEMISTRY; DRUG EFFECT; DRUG SENSITIVITY; HUMAN; ISOLATION AND PURIFICATION; MALARIA FALCIPARUM; MEDICINAL PLANT; METABOLISM; METHODOLOGY;

PLASMODIUM FALCIPARUM;

ANIMALS; ANTIMALARIALS; GLUTATHIONE; HEMIN; HUMANS; INHIBITORY CONCENTRATION 50; MACROPHAGE MIGRATION-INHIBITORY FACTORS; MALARIA, FALCIPARUM; PARASITIC SENSITIVITY TESTS; PLANT EXTRACTS; PLANTS, MEDICINAL; PLASMODIUM FALCIPARUM;

EID: 0035996090     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/dkf089     Document Type: Article

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