SCOPUS 정보 검색 플랫폼

Volumn 30, Issue 7, 2002, Pages 771-777

The pharmacokinetics of a thiazole benzenesulfonamide β3-adrenergic receptor agonist and its analogs in rats, dogs, and monkeys: Improving oral bioavailability

(16) Stearns, Ralph A a Miller, Randy R b Tang, Wei b Kwei, Gloria Y c Tang, Frank S a Mathvink, Robert J b Naylor, Elizabeth M b Chitty, Dawn c Colandrea, Vincent J a Weber, Ann E b Colletti, Adria E b Strauss, John R c Keohane, Carol Ann a Feeney, William P a Iliff, Susan A b Chiu, Shuet Hing Lee b

a Drug Metabolism II (United States)

b Department of Medicinal Chemistry ^* (United States)

c MERCK RESEARCH LABORATORIES (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZENESULFONAMIDE DERIVATIVE; BETA 3 ADRENERGIC RECEPTOR STIMULATING AGENT; N [4 [2 [2 (3 PYRIDINYL)MORPHOLIN 4 YL]ETHYL]PHENYL] 4 [4 [4 (TRIFLUOROMETHYL)PHENYL]THIAZOL 2 YL]BENZENESULFONAMIDE; N [4 [2 [[2 HYDROXY 2 (PYRIDIN 2 YL)ETHYL]AMINO]ETHYL]PHENYL] 4 [4 (4 TRIFLUOROMETHYLPHENYL)THIAZOL 2 YL]BENZENESULFONAMIDE; N [4 [2 [[2 HYDROXY 2 (PYRIDIN 3 YL)ETHYL]AMINO]ETHYL]PHENYL] 4 [4 (4 TRIFLUOROMETHYLPHENYL)THIAZOL 2 YL]BENZENESULFONAMIDE; N [4 [2 [ETHYL [2 HYDROXY 2 (3 PYRIDINYL)ETHYL]AMINO]ETHYL]PHENYL] 4 [4 [4 (TRIFLUOROMETHYL)PHENYL]THIAZOL 2 YL]BENZENESULFONAMIDE; PRODRUG; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG; BENZENESULFONAMIDE; BETA 3 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; SULFONAMIDE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOG; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG DESIGN; DRUG DETERMINATION; DRUG EXCRETION; DRUG METABOLISM; DRUG STRUCTURE; FIRST PASS EFFECT; HYDROGEN BOND; INTESTINE ABSORPTION; LIVER BLOOD FLOW; LIVER METABOLISM; MALE; MONKEY; NONHUMAN; PRIORITY JOURNAL; RAT; SPECIES DIFFERENCE; ANIMAL; BIOAVAILABILITY; CHEMISTRY; DRUG POTENTIATION; DRUG SCREENING; MACACA; METABOLISM; ORAL DRUG ADMINISTRATION; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ADMINISTRATION, ORAL; ADRENERGIC BETA-AGONISTS; ANIMAL; BIOLOGICAL AVAILABILITY; DOGS; DRUG EVALUATION, PRECLINICAL; MACACA MULATTA; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, BETA-3; SULFONAMIDES; THIAZOLES; ANIMALS;

ANIMALIA; CANIS FAMILIARIS;

EID: 0035987890 PISSN: 00909556 EISSN: None Source Type: Journal
DOI: 10.1124/dmd.30.7.771 Document Type: Article

Times cited : (18)

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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.