β3-Adrenoceptor agonist-induced increases in lipolysis, metabolic rate, facial flushing, and reflex tachycardia in anesthetized rhesus monkeys

Journal of Pharmacology and Experimental Therapeutics

Volumn 297, Issue 1, 2001, Pages 299-307

  Hom, G J ^a   Forrest, M J ^a   Bach, T J ^a   Brady, E ^a   Candelore, M R ^a   Cascieri, M A ^a   Fletcher, D J ^a   Fisher, M H ^a   Iliff, S A ^a   Mathvink, R ^a   Metzger, J ^a   Pecore, V ^a   Saperstein, R ^a   Shih, T ^a   Weber, A E ^a   Wyvratt, M ^a   Zafian, P ^a   Macintyre, D E ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 [4 (3 CYCLOPENTYLPROPYL) 4,5 DIHYDRO 4 OXO 1H TETRAZOL 1 YL] N [4 [2 [[2 HYDROXY 2 (3 PYRIDINYL)ETHYL]AMINO]ETHYL]PHENYL]BENZENESULFONAMIDE; BENZENESULFONAMIDE DERIVATIVE; BETA 3 ADRENERGIC RECEPTOR STIMULATING AGENT; N [4 2 [[2 HYDROXY 2 (3 PYRIDINYL)ETHYL]AMINO]ETHYL]PHENYL] 1 (4 OCTYLTHIAZOL 2 YL) 5 INDOLINESULFONAMIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIOVASCULAR FUNCTION; CONTROLLED STUDY; DRUG EFFECT; ENERGY EXPENDITURE; FLUSHING; LIFE EXPECTANCY; LIPOLYSIS; METABOLIC RATE; MITOCHONDRIAL MEMBRANE; NONHUMAN; NORADRENALIN RELEASE; PRIORITY JOURNAL; QUALITY OF LIFE; RHESUS MONKEY; TACHYCARDIA; VASCULAR RESISTANCE;

ADENYLATE CYCLASE; ADRENERGIC BETA-AGONISTS; ANESTHESIA; ANIMALS; CHO CELLS; CRICETINAE; DOSE-RESPONSE RELATIONSHIP, DRUG; FLUSHING; HEART RATE; INDOMETHACIN; LIPOLYSIS; MACACA MULATTA; MALE; PROPANOLAMINES; PROPRANOLOL; RECEPTORS, ADRENERGIC, BETA-3; REFLEX;

EID: 0035082116     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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