Determination of protein allergenicity: Studies in rats

Toxicology Letters

Volumn 120, Issue 1-3, 2001, Pages 171-180

  Penninks, André H ^a   Knippels, Leon M J ^a  

^a TNO   (Netherlands)

Author keywords

BN rat model; GMOs; Oral sensitization; Protein allergenicity

Indexed keywords

FOOD ALLERGEN; IMMUNOGLOBULIN E; IMMUNOLOGICAL ADJUVANT; OVALBUMIN; PROTEIN ANTIBODY; PROTEIN CM; PROTEIN HEW; UNCLASSIFIED DRUG;

ALLERGENICITY; ALLERGY TEST; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; BLOOD PRESSURE; BREATHING RATE; CONFERENCE PAPER; CONTROLLED STUDY; FOOD ALLERGY; IMMUNOGLOBULIN PRODUCTION; INTESTINE MUCOSA PERMEABILITY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; RAT; RELIABILITY; SENSITIZATION;

ANIMALS; ANTIBODY FORMATION; DISEASE MODELS, ANIMAL; EGG PROTEINS; FOOD HYPERSENSITIVITY; LACTOGLOBULINS; MALE; MILK PROTEINS; OVALBUMIN; RATS; RATS, INBRED BN;

EID: 0035977910     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(01)00275-2     Document Type: Conference Paper

References (37)

1. Brown Norway rat model of food allergy: Effect of plant components on the development of oral sensitization
2. Production of circulating reaginic (IgE) antibodies by oral administration of ovalbumin to rats
3. Rapid transepithelial antigen transport in rat jejunum: Impact of sensitization and the hypersensitivity reaction
4. Allergenicity and antigenicity of chicken egg ovomucoid (Gal d III) compared with ovalbumin (Gal d I) in children with egg allergy and in mice
5. The induction of respiratory allergy in guinea pigs following intradermal injection of trimellitic anhydride: A comparison with the response to 2,4-dinitrochlorobenzene
6. Adverse reactions to food
7. Systemic tolerance and secretory immunity after oral immunisation
8. Gastrointestinal food hypersensitivity; basic mechanisms of pathophysiology
9. Divergent antibody isotope responses induced in mice by systemic exposure to proteins: A comparison of ovalbumin with bovine serum albumin
10. The modified anaphylaxis hypothesis for cot death. Anaphylactic sensitization in guinea pigs fed cow's milk
11. Purification of egg white allergens
12. The atopic dog: A model for food allergy
13. Mononuclear cells from infants allergic to cow's milk secrete tumor necrosis factor, altering intestinal function
14. Serological responses induced in mice by immunogenic proteins and by protein respiratory allergens
15. Characteristics of antibody responses induced in mice by protein allergens
16. Murine model of IgE production with a predominant Th2-response by feeding protein antigen without adjuvants
17. Nitric oxide synthesis inhibition increases epithelial permeability via mast cells
18. Oral sensitization to food proteins: A Brown Norway rat model
19. Continued expression of anti soy-protein antibodies in rats bred on a soy-protein free diet; the importance of dietary control in oral sensitization research
20. Humoral and cellular immune responses in different rat strains upon oral exposure to ovalbumin
21. Immune-mediated effects upon oral challenge of ovalbumin sensitized Brown Norway rats; further characterization of a rat food allergy model
22. Comparison of antibody responses to hen's egg and cow's milk-proteins in orally sensitized rats and human patients
23. A murine model for IgE-mediated cow's milk hypersensitivity
24. A murine model of peanut anaphylaxis: T- and B-cell responses to a major peanut allergen mimic human responses
25. Assessment of the allergenic potential of foods derived from genetically engineered crop plants
26. Nutrition and asthma
27. The regulation of the immune responses to dietary protein antigens
28. Passive cutaneous anaphylaxis
29. The effect of age on IgE production in rats
30. Ability of a new infant formula prepared from partially hydrolyzed whey to induce anaphylactic sensitization; evaluation in a guinea pig model
31. Release of the mucosal mast cell granule chymase, rat mast cell protease II, during anaphylaxis is associated with the rapid development of paracellular permeability to macromolecules in rat jejunum
32. Immunogenicity testing of food proteins: In vivo and in vitro trials in rats
33. Immune responses to fed protein antigens in mice. Systemic tolerance or priming is related to age at which antigen is first encountered
34. Modulation of intestinal and systemic immune responses to a fed protein antigen in mice
35. Principles and characteristics of food allergens
36. Mucosal mast cell activation patterns in the rat following repeated feeding of antigen
37. Assessment of allergic potential of (novel) foods