Cell cycle controlling the silencing and functioning of mammalian activators

Current Biology

Volumn 11, Issue 21, 2001, Pages 1695-1699

  Mullen, Alan C ^a   Hutchins, Anne S ^a   Villarino, Alejandro V ^a   Lee, Hubert W ^a   High, Frances A ^a   Cereb, Nezih ^b   Yang, Soo Y ^b   Hua, Xianxin ^a   Reiner, Steven L ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b and Center for Genetic Polymorphism   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALIA;

EID: 0035975987     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(01)00533-4     Document Type: Article

References (22)

1. Lineage commitment in the immune system: The T helper lymphocyte grows up
2. A novel transcription factor, T-bet, directs Th1 lineage commitment
3. H1 cells before IL-12-dependent selection
4. The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells
5. Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment
6. Heterogeneity of helper/inducer T lymphocytes. I. Lymphokine production and lymphokine responsiveness
7. Inhibition of Th1 development mediated by GATA-3 through an IL-4-independent mechanism
8. Role of DNA replication in the repression of silent mating type loci in yeast
9. Overcoming telomeric silencing: A trans-activator competes to establish gene expression in a cell cycle-dependent way
10. Induction of Cytotoxic T Lymphocyte Antigen 4 (CTLA-4) restricts clonal expansion of helper T cells
11. Reversibility of T helper I and 2 populations is lost after long-term stimulation
12. Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets
13. Abrogation of TGFβ signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease
14. Helper T cell differentiation is controlled by the cell cycle
15. Instruction for cytokine expression in T helper lymphocytes in relation to proliferation and cell cycle progression
16. Functional flexibility in T cells: Independent regulation of CD4+ T cell proliferation and effector function in vivo
17. Cell division is not a "clock" measuring acquisition of competence to produce IFN-γ or IL-4
18. Mimosine arrests proliferating human cells before onset of DNA replication in a dose-dependent manner
19. Regulated expression of the beta-globin gene locus in synthetic nuclei
20. Establishment of transcriptional silencing in the absence of DNA replication
21. DNA replication-independent silencing in S. cerevisiae
22. Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation