Flies, clocks and evolution

Philosophical Transactions of the Royal Society B: Biological Sciences

Volumn 356, Issue 1415, 2001, Pages 1769-1778

  Rosato, E ^a   Kyriacou, C P ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Circadian; Clock; Drosophila; Evolution; Insects

Indexed keywords

ANTHERAEA PERNYI; CIRCADIAN RHYTHM; GENE EXPRESSION; GENE FUNCTION; GENETIC REGULATION; GENETIC SIMILARITY; GENETIC VARIANCE; MAMMAL CELL; MODEL; MOLECULAR EVOLUTION; PHENOTYPE;

CIRCADIAN RHYTHM;

ANTHERAEA PERNYI; BOMBYX MORI; DROSOPHILA MELANOGASTER; HEXAPODA; LEPIDOPTERA; MAMMALIA; MELANOGASTER;

EID: 0035969439     PISSN: 09628436     EISSN: None     Source Type: Journal    
DOI: 10.1098/rstb.2001.0961     Document Type: Conference Paper

References (85)

1. A mutant Drosophila homolog of mammalian Clock disrupts circadian rhythms and transcription of period and timeless
2. The period gene controls courtship song cycles in Drosophila melanogaster
3. Requirement of circadian genes for cocaine sensitization in Drosophila
4. Circadian regulation of a Drosophila homolog of the mammalian Clock gene: PER and TIM function as positive regulators
5. dCLOCK is present in limiting amounts and likely mediates daily interactions between the dCLOCK-CYC transcription factor and the PER-TIM complex
6. Restoration of circadian behavioural rhythms by gene transfer in Drosophila
7. A second timeless gene in Drosophila shares greater sequence similarity with mammalian tim
8. Cycling vrille expression is required for a functional Drosophila clock
9. Conformational study of the Thr-Gly repeat in the Drosophila clock protein period
10. Light-dependent sequestration of Timeless by Cryptochrome
11. Making time with the human genome: New clock gene relatives
12. Functional and evolutionary implications of natural variation in clock genes
13. Length polymorphism in the threonineglycine encoding repeat region of the period gene in Drosophila
14. A latitudinal cline in a Drosophila clock gene
15. Closing the circadian loop: CLOCK induced transcription of its own inhibitors, per and tim
16. The period E-box is sufficient to drive circadian oscillation of transcription in vivo
17. Temporal phosphorylation of the Drosophila period protein
18. CRY, a Drosophila clock and light-regulated cryptochrome, is a major contributor to circadian rhythm resetting and photosensitivity
19. A unique circadian-rhythm photoreceptor
20. The regulation of circadian clocks by light in fruitflies and mice
21. Alternative initiation of translation and time-specific phosphorylation yield multiple forms of the essential clock protein Frequency
22. L
23. The vrille gene of Drosophila is a maternal enhancer of decapentaplegic and encodes a new member of the bZIP family of transcription factors
24. Interlocked feedback loops within the Drosophila circadian oscillator
25. Sex-linked period genes in the silkmoth, Antheraea pernyi: Implications for circadian clock regulation and the evolution of sex chromosomes
26. A time-less function for mouse timeless
27. Different period gene repeats take 'turns' at fine tuning the circadian clock
28. Feedback of the Drosophila period gene product on circadian cycling of its messenger RNA levels
29. PAS is a dimerization domain common to Drosophila Period and several transcriptions factors
30. Regulation of the Drosophila protein timeless suggests a mechanism for resetting the circadian clock by light
31. DCRY is a Drosophila photoreceptor protein implicated in light entrainment of circadian rhythm
32. Genes, molecules and mechanisms of circadian clock outputs in insects
33. The Drosophila clock gene double-time encodes a protein closely related to human casein kinase Iε
34. Clock mutants of Drosophila melanogaster
35. Spectral analysis of Drosophila courtship songs
36. Squaring up the E-box
37. Clock mutations alter developmental timing in Drosophila
38. Resetting the Drosophila clock by photic regulation of PER and PER-TIM complex
39. The Drosophila CLOCK protein undergoes daily rhythms in abundance, phosphorylation and interactions with the PER-TIM complex
40. PER and TIM inhibit the DNA binding activity of a Drosophila CLOCK-CYC/dBMAL1 heterodimer without disrupting formation of the heterodimer: A basis for circadian transcription
41. Thermally regulated translational control of FRQ mediates aspects of temperature responses in the Neurospora circadian clock
42. Expression of a Drosophila mRNA is under circadian clock control during pupation
43. Positional syntenic cloning and functional characterization of the mammalian circadian mutation tau
44. Specific sequences outside of the E-box are required for proper per expression and behavioral rescue
45. A molecular rhythm mediating circadian clock output in Drosophila
46. How a circadian clock adapts to seasonal decreases in temperature and day length
47. Positional cloning and sequence analysis of the Drosophila clock gene, timeless
48. A role for the proteasome in the light response of the timeless clock protein
49. A new biological rhythm mutant of Drosophila melanogaster that identifies a gene with an essential embryonic function
50. Big flies, small repeats - The Thr-Gly region of the period gene in diptera
51. Conserved regions of the timeless (tim) clock gene in Drosophila analyzed through phylogenetic and functional studies
52. Differential regulation of circadian pacemaker output by separate clock genes in Drosophila
53. Molecular evolution of a repetitive region within the per gene of Drosophila
54. Molecular coevolution within a Drosophila clock gene
55. The period gene of Drosophila carries species-specific behavioural instructions
56. The clock gene period of the housefly, Musca domestica, rescues behavioral rhythmicity in Drosophila melanogaster. Evidence for intermolecular coevolution?
57. Double-time is a new Drosophila clock gene that regulates Period protein accumulation
58. Molecular analysis of the period locus in Drosophila melanogaster and identification of a transcript involved in biological rhythms
59. Evolution and phylogenetic utility of the period gene in Lepidoptera
60. A pdf neuropeptide gene mutation and ablation of PDF neurons each cause severe abnormalities of behavioral circadian rhythms in Drosophila
61. Comparing clockworks: Mouse versus fly
62. Cloning of a structural and functional homolog of the circadian clock gene period, from the giant silkmoth Antheraea pernyi
63. Circadian systems: Different levels of complexity
64. Mutational mechanisms, phylogeny, and evolution of a repetitive region within a clock gene of Drosophila melanogaster
65. Conceptual translation of timeless reveals alternative initiating methionines in Drosophila
66. Mutation rate, linkage disequilibrium, and selection in the repetitive region of the period gene in Drosophila melanogaster
67. A Timeless-independent function for Period proteins in the Drosophila clock
68. Cycle is a second bHLH-PAS clock protein essential for circadian rhythmicity and transcription of Drosophila period and timeless
69. Regulation of nuclear entry of the Drosophila clock proteins Period and Timeless
70. The Drosophila takeout gene is a novel molecular link between circadian rhythms and feeding behavior
71. Circadian clock neurons in the silkmoth Antheraea pernyi: Novel mechanisms of Period protein regulation
72. Period protein is necessary for circadian control of egg hatching behaviour in the silkmoth Antheraea pernyi
73. Natural variation in a Drosophila clock gene and temperature compensation
74. Loss of circadian behavioural rhythms and per RNA oscillations in the Drosophila mutant timeless
75. Rhythmic expression of timeless - A basis for promoting circadian cycles in period gene autoregulation
76. Interacting molecular loops in the mammalian circadian clock
77. Targeted disruption of the mPer3 gene: Subtle effects on circadian clock function
78. b mutation identifies cryptochrome as a circadian photoreceptor in Drosophila
79. Changes in period mRNA levels in the brain and division of labor in honey bee colonies
80. Nuclear entry of the circadian regulator mPER1 is controlled by mammalian casein kinase I epsilon
81. Circadian rhythms in Drosophila can be driven by period expression in a restricted group of central brain cells
82. Analysis of the circadian clock gene period in the sheep blow fly Lucilia cuprina
83. Dimerization and nuclear entry of mPER proteins in mammalian cells
84. A light entrainment mechanism for the Drosophila circadian clock
85. The mPer2 gene encodes a functional component of the mammalian circadian clock