Specific sequences outside the E-box are required for proper per expression and behavioral rescue

Journal of Biological Rhythms

Volumn 15, Issue 6, 2000, Pages 472-482

  Lyons, Lisa C ^a   Darlington, Thomas K ^b   Hao, Haiping ^c   Houl, Jerry ^a   Kay, Steve A ^b   Hardin, Paul E ^a  

^a University of Houston   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c ROHM AND HAAS COMPANY   (United States)

Author keywords

Behavior; Circadian rhythms; Drosophila; Gene expression; Period; Transcription

Indexed keywords

ANIMALIA; INSECTA;

EID: 0034465626     PISSN: 07487304     EISSN: None     Source Type: Journal    
DOI: 10.1177/074873040001500604     Document Type: Article

References (34)

1. A mutant Drosophila homolog of mammalian Clock disrupts circadian rhythms and transcription of period and timeless
2. Cycling vrille expression is required for a fully functional Drosophila clock
3. Drosophila photoreceptors contain an autonomous circadian oscillator that can function without period mRNA cycling
4. Temporally regulated entry of the Drosophila period protein contributes to the circadian clock
5. The period E-box is sufficient to drive circadian oscillation of transcription in vivo
6. Closing the circadian feedback loop: CLOCK induced transcription of its own inhibitors, period and timeless
7. Molecular bases for circadian clocks
8. Temporal phosphorylation of the Drosophila period protein
9. Requirement for period gene expression in the adult and not during development for locomotor activity rhythms of imaginal Drosophila melanogaster
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11. Molecular and behavioral analysis of four period mutants in Drosophila melanogaster encompassing extreme short, novel long, and unorthodox arrhythmic types
12. 0 and per- mutants
13. A circadian enhancer mediates PER-dependent mRNA cycling in Drosophila
14. The 69 bp circadian regulatory sequence (CPS) mediates per-like developmental, spatial, and circadian expression and behavioral rescue in Drosophila
15. Feedback of the Drosophila period gene product on circadian cycling of its messenger RNA levels
16. Circadian oscillations in period gene mRNA levels are transcriptionally regulated
17. Octamer primed cycle sequencing: Design of an optimized primer library
18. The basic-helix-loop-helix-PAS orphan MOP3 forms transcriptionally active complexes with circadian and hypoxia factors
19. A molecular mechanism regulating rhythmic output from the suprachiasmatic circadian clock
20. The Drosophila clock gene double-time encodes a protein closely related to human casein kinase Iε
21. PER and TIM inhibit the DNA binding activity of a dCLOCK-CYC/dBMAL1 heterodimer without disrupting formation of the heterodimer: A basis for circadian transcription
22. Spatial and temporal expression of the period gene in Drosophila melanogaster
23. The period gene encodes a predominantly nuclear protein in adult Drosophila
24. Localized heat-shock induction in Drosophila melanogaster
25. Double-time is a new Drosophila clock gene that regulates PERIOD protein accumulation
26. Suppression of PERIOD protein abundance and circadian cycling by the Drosophila clock mutation timeless
27. CYCLE is a second bHLH-PAS clock protein essential for circadian rhythmicity and transcription of Drosophila period and timeless
28. Loss of circadian behavioral rhythms and per RNA oscillations in the Drosophila mutant timeless
29. Rhythmic expression of timeless: A basis for promoting circadian cycles in period gene autoregulation
30. Construction of mutant and chimeric genes using the polymerase chain reaction
31. Block in nuclear localization of period protein by a second clock mutation, timeless
32. CNS midline enhancers of the Drosophila slit and Toll genes
33. Circadian fluctuations of period protein immunoreactivity in the CNS and the visual system of Drosophila
34. A post-transcriptional mechanism contributes to circadian cycling of a per-b-galactose fusion protein