MDR1 P-glycoprotein Reduces Influx of Substrates without Affecting Membrane Potential

Journal of Biological Chemistry

Volumn 276, Issue 52, 2001, Pages 49053-49060

  Luker, Gary D ^a,b   Flagg, Thomas P ^b   Sha, Qun ^b,c   Luker, Kathryn E ^a,b   Pica, Christina M ^a,b   Nichols, Colin G ^b   Piwnica Worms, David ^a,b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MARYLAND MEDICAL SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; CELLS; CHEMOTHERAPY; DRUG PRODUCTS;

MACROSCOPIC CONDUCTANCE;

PROTEINS;

ANTINEOPLASTIC AGENT; DAUNORUBICIN; ELACRIDAR; METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M; MULTIDRUG RESISTANCE PROTEIN; PACLITAXEL; POTASSIUM ION; TETRAPHENYLBORON; TRITIUM; ZOSUQUIDAR; GLYCOPROTEIN P; IONOPHORE; TECHNETIUM COMPLEX; VALINOMYCIN;

ARTICLE; CELL STRAIN MCF 7; CYTOTOXICITY; DRUG TRANSPORT; HUMAN; HUMAN CELL; IMAGING; MEMBRANE CONDUCTANCE; MEMBRANE TRANSPORT; PRIORITY JOURNAL; PROTEIN EXPRESSION; ADENOCARCINOMA; BREAST TUMOR; CELL CULTURE; CELL MEMBRANE; CELL MEMBRANE POTENTIAL; FEMALE; METABOLISM; MULTIDRUG RESISTANCE; PATCH CLAMP; PHYSIOLOGY; TRANSPORT AT THE CELLULAR LEVEL;

MINK CELL FOCUS-FORMING VIRUS;

ADENOCARCINOMA; BIOLOGICAL TRANSPORT; BREAST NEOPLASMS; CELL MEMBRANE; DRUG RESISTANCE, MULTIPLE; FEMALE; HUMAN; IONOPHORES; MEMBRANE POTENTIALS; ORGANOTECHNETIUM COMPOUNDS; P-GLYCOPROTEIN; PATCH-CLAMP TECHNIQUES; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; TUMOR CELLS, CULTURED; VALINOMYCIN;

EID: 0035966014     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M105192200     Document Type: Article

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