What is the precise role of human MDR 1 protein in chemotherapeutic drug resistance?

Current Pharmaceutical Design

Volumn 6, Issue 3, 2000, Pages 241-260

  Roepe, Paul D ^a  

^a GEORGETOWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; MULTIDRUG RESISTANCE PROTEIN;

CANCER CHEMOTHERAPY; CANCER RESEARCH; DRUG TRANSPORT; DRUG UPTAKE; HUMAN; MULTIDRUG RESISTANCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REVIEW;

EID: 0034083415     PISSN: 13816128     EISSN: None     Source Type: Journal    
DOI: 10.2174/1381612003401163     Document Type: Review

References (115)

1. Danø, K. Biochim. et Biophys. Acta 1973, 323, 466.
2. Burchenal, J.H., Robinson, E., Johnston, S.F. & Kushida, M.M. Science 1950, 111, 116.
3. Houghton, P.J. & Kaye, S.B. J. Natl. Inst. Of Health 1994, 6, 55.
4. Wadkins, R. M. & Roepe, P.D. Int. Rev. Cytol. 1997, 171, 121.
5. Robinson, L.J., Roberts, W.K., Ling, T.T., Lamming, D., Sternberg, S.S. & Roepe, P.D. Biochemistry 1997, 36, 11169.
6. Biedler, J.L. & Riehm, H. Cancer Res. 1970, 30, 1174.
7. Endicott, J.A. & Ling, V. Annu. Rev. Biochem. 1989, 58, 137.
8. Chen, C.-j., Chin, J.E., Ueda, K., Clark, D.P., Pastan, I., Gottesman, M.M. & Roninson, I.B. Cell 1986, 47, 381.
9. Gros, P., Croop, J. & Housman, D. Cell 1986, 47, 371.
10. Scotto, K. W. , Biedler, J.L. & Melera, P. W. Science 1986, 232, 751.
11. Gerlach, J.H., Endicott, J.A., Juranka, P.F., Henderson, G., Sarangi, F. , Deuchars, K.L. & Ling, V. (Nature London) 1986, 324, 485.
12. Cornwell, M.M., Safa, A.R., Felsted, R.L., Gottesman, M.M. & Pastan, I. Proc. Natl. Acad. Sci. 1986, 83, 3847.
13. Safa, A.R., Stern, R.K., Choi, K., Agresti, M., Tamai, L, Mehta, N.D. & Roninson, I.B. Proc. Natl. Acad. Sci. 1990, 87, 7225.
14. Lankelma, J., Spoelstra, E.C., Dekker, H. & Broxterman, H.J. Biochim. et Biophys. Acta 1990, 1055, 217.
15. Roepe, P.D. Biochemistry 1992, 31, 12555.
16. Ruetz, S. & Gros, P. J. Biol. Chem. 1994, 269, 12277.
17. Sharom, F.J., Yu, X. & Doige, C.A. J. Biol. Chem. 1993, 268, 24197.
18. Schlemmer, S.R. & Sirotnak, F.M. J. Biol. Chem. 1994, 269, 31059.
19. Bornmann, W. G. & Roepe, P.D. Biochemistry 1994, 33, 12665.
20. Valverde, M., Diaz, M., Sepulveda, F.V., Gill, D.R., Hyde, S.C. & Higgins, C.F. Nature 1992, 355, 830.
21. Gill, D.R., Hyde, S., Higgins, C.F., Valverde, M.A., Mintenig, G.M. & Sepúlveda, F.V. Cell 1992, 71, 23.
22. Altenberg, G.A., Deitmer, J.W., Glass, D.C. & Reuss, L. Cancer Res. 1994, 54, 618.
23. Bear, C.E. Biochem. & Biophys. Res. Comm. 1994, 200, 513.
24. Ehring, G.R., Osipchuk, Y.V. & Cahalan, M.D. J. Gen. Physiol. 1994, 104, 1129.
25. Luckie, D.B., Krouse, M.E., Harper, K.L., Law, T.C. & Wine, J.J. Am. J. Physiol. 1994, 267, C650.
26. Dong, Y.-j., Chen, G., Duran, G.E., Kouyama, K., Chao, A., Sikic, B.I., Gollapudi, S.V., Gupta, S. & Gardner, P. Cancer Res. 1994, 54, 5024.
27. Luckie, D.B., Harper, K.L., Krouse, M.E., Law, T.C., Sikic, B. & Wine, J.J. Biophys. J. 1995, 68, A272.91
28. Han, E.S., Vanoye-Trevino, C., Altenberg, G.A. & Reuss, L. Biophys. J. 1995, 68, A273.95.
29. Hardy, S.P., Goodfellow, H.R., Valverde, M.A., Gill, D.R., Sepulveda, F.V. & Higgins, C.F. EMBO J. 1995, 14 , 68.
30. Hoffman, M.M., Wei, L.Y. & Roepe, P.D. J. Gen. Physiol. 1996, 108, 295.
31. Hoffman, M.M. & Roepe, P.D. Biochemistry 1997, 36, 11153.
32. Riordan, J.R., Rommens, J.M., Kerem, B.-S., Alon, N., Rozmahel, R., Grzelczak, Z., Zielenski, J., Lok, S., Plavsic, N., Chou, J.-L., Drumm, M.L., Iannuzzi, M.C., Collins, F.C. & Tsui, L.-C. Science 1989, 245, 1066.
33. Bear, C.E., Li, C., Kartner, N., Bridges, R.J., Jensen, T.J., Ramjeesingh, M. & Riordan, J.R. Cell 1992, 68, 809.
34. Aguilar-Bryan, L., Nichols, C.G., Wechsler, S.W., Clement, J.P., Boyd, A.E. Gonzalez, G., Herrera-Sosa, H., Nguy, K., Bryan, J. & Nelson, D.A. Science 1995, 268, 423.
35. Higgins, C.F. Ann. Rev. Cell Biol. 1992, 8, 67.
36. Stein, W.D. Physiol. Rev. 1997, 77, 545.
37. Gottesman, M.M. & Pastan, I. Annu. Rev. Biochem. 1993, 62, 385.
38. Higgins, C.F. & Gottesman, M.M. Trends in Biochem. Sci. 1992, 17, 18.
39. Pearce, H.L., Safa, A.R., Bach, N.J., Winter, M.A., Cirtain, M.C. & Beck, W.T. Proc. Natl. Acad. Sci. U.S.A. 1989, 86, 5128.
40. Wigler, P.W. J. Bioenerg. and Biomembr. 1996, 28, 279.
41. Wadkins, R.M. & Houghton, P.J. Biochim. et Biophys. Acta 1993, 1153, 225.
42. Horio, M., Gottesman, M.M. & Pastan, I. Proc. Natl. Acad. Sci., U.S.A. 1988, 85, 3580.
43. Ruetz, S., Raymond, M. & Gros, P. Proc. Natl. Acad. Sci. 1993, 90, 11588.
44. Fritz, F., Howard, E., Hoffman, M.M. & Roepe, P.D. Biochemistry 1999, 38, 4214.
45. Santai, C.T., Fritz, F. & Roepe, P.D. Biochemistry 1999, 38, 4227.
46. Roepe, P.D., Wei, L.-Y., Hoffman, M.M. & Fritz, F. J. of Bioenergetics and Biomembranes 1996, 28, 541.
47. Demant, E.J.F., Sehested, M. & Jensen, P.B. Biochim et Biophys. Acta 1990, 1055 ,117.
48. Roepe, P.D. Trends, in Pharm. Sci. 1994, 15, 445.
49. Hammond, J.R., Johnstone, R.M. & Gros, P. Cancer Res. 1989, 49, 3867.
50. Robinson, L.J. & Roepe, P.D. Biochem. Pharm. 1996, 52, 1081.
51. Roepe, P.D. Biochim. et Biophys. Acta 1995, 1241, 385.
52. Eytan, G.D., Regev, R. & Assaraf, Y.G. J. Biol. Chem. 1996, 271, 3172.
53. Ambudkar, S.V., Cardarelli, C.O., Pashinsky, I. & Stein, W.D. J. Biol. Chem. 1997, 272, 21160.
54. Ruetz, S. & Gros, P. Cell 1994, 77, 1071.
55. Schaffer J.E. & Lodish, H.F. Cell 1994, 79, 427.
56. Coley, H.M., Amos, W.B., Twentyman, P.R. & Workman, P. Br. J. Cancer 1993, 67, 1316.
57. Roepe, P.D., Wei, L.-Y., Cruz, J. & Carlson, D. Biochemistry 1993, 32, 11042.
58. Mayer, L.D., Bally, M.B., Hope, M.J. & Cullis, P.R. Biochim. et Biophys. Acta 1985, 816, 294.
59. Praet, M., Defrise-Quertain, F., & Ruysschaert, J.M. Biochim. et Biophys. Acta 1993, 1148, 342.
60. Mayer, L.D., Bally, M.B. & Cullis, P.R. Biochim. et Biophys. Acta 1986, 857, 123.
61. Bally, M.B., Hope, M.J., Van Echteid, C.J.A. & Cullis P.R. Biochim. et Biophys. Acta 1985, 812, 66.
62. Maurer-Spurej, E., Wong, K.F., Maurer, N., Fenske, D.B. & Cullis, P.R. Biochimica et Biophysica Acta 1999, 1416, 1.
63. Luz, J.G., Wei, L.-Y., Basu, S. & Roepe, P.D. Biochemistry 1994, 33, 7239.
64. Altenberg, G.A., Young, G., Horton, J.K., Glass, D., Belli, J.A. & Reuss, L. Proc. Natl. Acad. Sci. U.S.A. 1993, 90, 9735.
65. Lee, B.S., Gunn, R. & Kopito, R.R. J. Biol. Chem. 1991, 266, 11488.
66. Belhoussine, R., Morjani, H., Sharanov, S., Ploton, D. & Manfait, M. Int. J. Cancer 1999, 81, 8 1.
67. Altan, N., Chen, Y., Schindler, M. & Simon, S. M. J. Exp. Med. 1998, 187, 1583.
68. Stutts, M.J., Gabriel, S.E., Olsen, J.C., Gatzy, J.T., O'Connell, T.L., Price, E.M. & Boucher, R.C. J. Biol. Chem. 1993, 268, 20653.
69. Wei, L.Y., Stutts, M.J., Hoffman, M.M. & Roepe, P.D. Biophys. J. 1995, 69, 883.
70. Gadsby, D.C. & Nairn, A. Trends, in Biochem. Sci. 1994, 19, 513.
71. Smit, J.J.M., Schinkel, A.H., Oude Elferink, R.P.J., Groen, A.K., Wagenaar, E., van Deemter, L., Mol, C.A.A.M., Ottenhoff, R., van der Lugt, N.M.T., van Roon, M.A., van der Valk, M.A., Offerhaus, G.J.A., Berns, A.J.M. & Borst, P. Cell 1993, 75, 451.
72. Schinkel, A.H. Int. J. of Clin. Pharm. & Ther. 1998, 36, 9.
73. Komura, J., Tamai, I., Senmaru, M., Terasaki, T., Sai, Y., & Tsuji, A. J. of Neurochemistry 1996, 67, 330.
74. Hirohashi, T., Terasaki, T., Shigetoshi, M., & Sugiyama, Y. J. of Pharm. & Exp. Therapeutics 1997, 280, 813.
75. Go, K.G. Advances & Tech. Standards in Neurosurgery 1997, 23, 47.
76. Wei, L.Y., Hoffman, M.M. & Roepe, P.D. Am. J. Physiol. 1997, 272, C1642.
77. Schmitt, E., Sane, A.T., Steyaert, A., Cimoli, G. & Bertrand, R. Biochem. Cell Biol. 1997, 75, 301.
78. Adams, J.M. & Cory, S. Science 1998, 281, 1322.
79. Schendel S.L., Xie, Z., Montai, M.O., Matsuyama, S., Montal, M. & Reed, J.C. Proc. Natl. Acad. Sci. 1997, 94, 5113.
80. Johnstone, R.W., Cretney, E. & Smyth, M.J. Blood 1999, 93, 1075.
81. Kojima, H., Endo, K., Moriyama, H., Tanaka, Y., Alnemri, E.S., Slapak, C.A., Teicher, B., Kufe, D. & Datta, R. J. Biol. Chem. 1998, 273, 16647.
82. Weisburg, J.H., Curcio, M., Caron, P.C., Raghi, G., Mechetner, E.B., Roepe, P.D. & Scheinberg, D.A. J. Exp. Med. 1996, 183, 2699.
83. Weisburg, J.H., Roepe, P.D., Dzekunov, S. & Scheinberg, D.A. J. Biol. Chem. 1999, 274, 10877.
84. Wang, C., Castro, A.F., Wilkes, D.M. & Altenberg, G.A. Biochem. J. 1999, 338, 77.
85. Bibi, E., Gros, P. & Kaback, H.R. Proc. Natl. Acad. Sci. 1993, 90, 9209.
86. Chambers, T.C. Germann, U.A., Gottesman, M.M., Pastan, I., Kuo, J.F. & Ambudkar, S.V. Biochemistry 1995, 34, 14156.
87. Bibi, E. & Beja, O. J. Biol. Chem. 1994, 269, 19910.
88. Dayan, G., Baubichon-Cortay, H., Jault, J.M., Cortay, J.C., Deleage, G. & DiPietro, A. J. Biol. Chem. 1996, 271, 11652.
89. Beja, O. & Bibi, E. Proc. Natl. Acad. Sci. 1996, 93, 5969.
90. George, A.M., Davey, M.W. & Mir, A.A. Arch. Biochem. Biophys. 1996, 333, 66.
91. Kuchler, K. & Thorner, J. Proc. Natl. Acad. Sci. 1992, 89, 2302.
92. Ballarin - Denti, A., Den Hollander, J.A., Sanders, D., Slayman, C.W. & Slayman, C.L. Biochim. et Biophys. Acta 1984, 778, 1.
93. Eytan, G.D., Borgnia, M.J., Regev, R., Assaraf, Y.G. J. Biol. Chem. 1994, 269, 26058.
94. Eytan, G.D., Regev, R., Oren, G. Assaraf, Y.G. J. Biol. Chem. 1996, 271, 3172.
95. Dong, M. Penin, F., Baggetoto, L.G. J. Biol. Chem. 1996, 46, 28875.
96. Shapiro, A.B. & Ling, V. J. Biol. Chem. 1995, 270, 16167.
97. Su, X.Z., Kirkman, L., Fujioka, H. & Wellems, T.E. Cell 1997, 91, 593.
98. Fiddock, D.A., Nomura, T., Talley, A.K., Su, X.Z., Cooper, R., Wooton, C. & Wellems, T.E. Proc. of Molec. Parasitol. Meeting 1999, 10, 18.
99. Martiney, J.A., Ferrer, A.S., Cerami, A., Dzekunov, S. & Roepe, P. In Transport and Trafficking in the Malaria - infected erythrocyte. Wiley, Chichester (Novartis Symposia Proceedings) 1999, 226, 265.
100. Martiney, J.A. & Roepe, P.D. Trends in Pharm. Sci. 1999, 20, 65.
101. Dzekunov, S. Ursos, L. & Roepe, P.D. Proc. of Molec. Parasitol. Meeting 1999, 10, 247C.
102. Wünsch, S., Sanchez, C.P., Gekle, M., Große - Wortmann, L., Wiesner, J. & Lanzer, M. J. Cell Biol. 1998, 140, 335.
103. Wellems, T.E., Wootton, J.C., Fujioka, H., Su, X.-z., Cooper, R., Baruch, D. & Fiddock, D.A. Cell 1998, 94, 285.
104. Wilson, C.M., Serrano, A.E., Wasley, A., Bogenschutz, M.P., Shankar, A.H. & Wirth, D.F. Science 1989, 244, 1184.
105. Barnes, D.A., Foote, S.J., Galatis, D., Kemp, D.J. & Cowman, A.F. EMBO J. 1992, 11, 3067.
106. Reed, M. & Cowman, A. Proc. of Molec. Parasitol. Meeting 1999, 10, 20.
107. Yanyon, A., Cabantchik, Z.I. & Ginsburg, H. EMBO J. 1984, 3, 2695.
108. De, D., Krogstad, F.M., Cogswell, F.B. & Krogstad, D.J. Am. J. Trop. Med. Hyg. 1996, 55, 579.
109. Parra - Lopez, C., Baer, M.T. & Groisman, E.A. EMBO J. 1993, 12, 4053.
110. Alloing, G., Trombe, M.C. & Claverys, J.P. Mol. Microbiol. 1990, 4, 633.
111. Trombe, M.C. Mol. Microbiol. 1993, 8, 199.
112. Cheng, J., Guffanti, A.A. & Krulwich, T.A. J. Biol. Chem. 1994, 269, 27365.
113. McCusker, J.H., Perlin, D.S. & Haber, J.E. Mol. & Cell. Biol. 1987, 7, 4082.
114. Perlin, D.S., Brown, C.L. & Haber, J.E. J. Biol. Chem. 1988, 263, 18118.
115. Perlin, D.S., Harris, S.L., Seto - Young, D. & Haber, J.E. J. Biol. Chem. 1989, 264, 21857.