Effects of membrane potential versus pH(i) on the cellular retention of doxorubicin analyzed via a comparison between cystic fibrosis transmembrane conductance regulator (CFTR) and multidrug resistance (MDR) transfectants

Biochemical Pharmacology

Volumn 52, Issue 7, 1996, Pages 1081-1095

  Robinson, Laura J ^a   Roepe, Paul D ^a,b  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

drug accumulation; efflux; intracellular pH; membrane potential; multidrug resistance

Indexed keywords

DOXORUBICIN; MULTIDRUG RESISTANCE PROTEIN; TRANSMEMBRANE CONDUCTANCE REGULATOR; VINBLASTINE;

ALKALINITY; ANIMAL CELL; ARTICLE; CELL LINE; CELL MEMBRANE POTENTIAL; CELL PH; CELL STRAIN 3T3; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG RETENTION; DRUG SENSITIVITY; DRUG TRANSPORT; FLUORESCENCE SPECTROSCOPY; GENE EXPRESSION; GENETIC TRANSFECTION; KINETICS; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL;

EID: 0030580034     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(96)81736-9     Document Type: Article

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