Effects of the Membrane Dipole Potential on the Interaction of Saquinavir with Phospholipid Membranes and Plasma Membrane Receptors of Caco-2 Cells

Journal of Biological Chemistry

Volumn 276, Issue 42, 2001, Pages 38457-38463

  Asawakarn, Tanong ^a   Cladera, Josep ^a   O'Shea, Paul ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSENSORS; DIELECTRIC PROPERTIES; DRUG DOSAGE; ENZYME INHIBITION; FLUORESCENCE; MOLECULAR STRUCTURE; PROTEINS;

MEMBRANE RECEPTORS;

CELL MEMBRANES;

1 (3 SULFONATOPROPYL) 4 [BETA [2 (DI N OCTYLAMINO) 6 NAPHTHYL]VINYL]PYRIDINIUM BETAINE; 6 OXOCHOLESTANOL; CALCIUM CHLORIDE; CALCIUM ION; CHOLESTANOL; CHOLESTEROL; COLCHICINE; FLUORESCENT DYE; GLYCOPROTEIN P; MEMBRANE RECEPTOR; METHYL BETA CYCLODEXTRIN; MULTIDRUG RESISTANCE PROTEIN; PHLORETIN; PHOSPHATIDYLETHANOLAMINE; POLYLYSINE; PROTEINASE INHIBITOR; SAQUINAVIR; UNCLASSIFIED DRUG; 1 (3 SULFONATOPROPYL) 4 (BETA (2 (DI N OCTYLAMINO) 6 NAPHTHYL)VINYL)PYRIDINIUM BETAINE; 1-(3-SULFONATOPROPYL)-4-(BETA-(2-(DI-N-OCTYLAMINO)-6-NAPHTHYL)VINYL)PYRIDINIUM BETAINE; 6-KETOCHOLESTANOL; BETA CYCLODEXTRIN; BETA CYCLODEXTRIN DERIVATIVE; CALCIUM; CHOLESTEROL DERIVATIVE; CYCLODEXTRIN; FLUORESCEIN DERIVATIVE; ION; METHYL-BETA-CYCLODEXTRIN; N FLUORESCEINYLPHOSPHATIDYLETHANOLAMINE; N-FLUORESCEINYLPHOSPHATIDYLETHANOLAMINE; PHOSPHOLIPID; PYRIDINIUM DERIVATIVE;

ARTICLE; CAVEOLA; CELL STRAIN CACO 2; CONTROLLED STUDY; DIPOLE; DRUG RECEPTOR BINDING; FLUORESCENCE; HUMAN; HUMAN CELL; LIPID BILAYER; MEMBRANE BINDING; MEMBRANE POTENTIAL; PHOSPHOLIPID MEMBRANE; PHOSPHOLIPID VESICLE; PRIORITY JOURNAL; BINDING COMPETITION; CELL LINE; CELL MEMBRANE; CELL MEMBRANE POTENTIAL; CHEMISTRY; DOSE RESPONSE; METABOLISM; PROTEIN BINDING; SIGNAL TRANSDUCTION; SPECTROFLUOROMETRY; TIME;

EQUIDAE; HUMAN IMMUNODEFICIENCY VIRUS;

BETA-CYCLODEXTRINS; BINDING, COMPETITIVE; CACO-2 CELLS; CALCIUM; CELL LINE; CELL MEMBRANE; COLCHICINE; CYCLODEXTRINS; DOSE-RESPONSE RELATIONSHIP, DRUG; FLUORESCEINS; HIV PROTEASE INHIBITORS; HUMANS; IONS; KETOCHOLESTEROLS; MEMBRANE MICRODOMAINS; MEMBRANE POTENTIALS; PHLORETIN; PHOSPHATIDYLETHANOLAMINES; PHOSPHOLIPIDS; POLYLYSINE; PROTEIN BINDING; PYRIDINIUM COMPOUNDS; SAQUINAVIR; SIGNAL TRANSDUCTION; SPECTROMETRY, FLUORESCENCE; TIME FACTORS;

EID: 0035914384     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M103269200     Document Type: Article

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