BDNF prevents NO mediated glutamate cytotoxicity in cultured cortical neurons

Brain Research

Volumn 756, Issue 1-2, 1997, Pages 200-204

  Kume, Toshiaki ^a   Kouchiyama, Hanae ^a   Kaneko, Satoshi ^a   Maeda, Takehiko ^a   Kaneko, Shuji ^a   Akaike, Akinori ^a   Shimohama, Shun ^a   Kihara, Takeshi ^a   Kimura, Jun ^a   Wada, Kazuyo ^b   Koizumi, Shinichi ^b  

^a KYOTO UNIVERSITY   (Japan)

^b CIBA GEIGY LTD   (Switzerland)

Author keywords

BDNF; Cerebral cortex; Glutamate; Neurotoxicity; NMDA; NO

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CALCIUM IONOPHORE; DIZOCILPINE; GLUTAMIC ACID; IONOMYCIN; LINSIDOMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; N(G) NITROARGININE; NITRIC OXIDE; NITRIC OXIDE DONOR; NITRIC OXIDE SYNTHASE INHIBITOR; S NITROSOCYSTEINE;

ANIMAL CELL; ARTICLE; BRAIN CELL; CELL PROTECTION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; FETUS; INCUBATION TIME; NERVE CELL CULTURE; NERVE CELL NECROSIS; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; RAT;

ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CALCIUM; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; GLUTAMIC ACID; IONOMYCIN; IONOPHORES; NEURONS; NEUROPROTECTIVE AGENTS; NITRIC OXIDE; PHOSPHORYLATION; RATS; RECEPTOR, CILIARY NEUROTROPHIC FACTOR; RECEPTORS, NERVE GROWTH FACTOR;

EID: 17644438639     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(97)00195-9     Document Type: Article

References (28)

1. 2 protects cultured cortical neurons against N-methyl-D-aspartate receptor-mediated glutamate cytotoxicity, Brain Res., 663 (1994) 237-243.
2. Akaike, A., Tamura, Y., Terada, K. and Nakata, N., Regulation by neuroprotective factors of NDMA receptor mediated nitric oxide synthesis in the brain and retina, Prog. Brain Res., 103 (1994) 391-403.
3. Barbacid, M., The Trk Family of neurotrophin receptors, J. Neurobiol., 25 (1994) 1386-1403.
4. Cheng, B. and Mattson, M.P., NT-3 and BDNF protect CNS neurons against metabolic/excitotoxic insults, Brain Res., 640 (1994) 56-67.
5. Choi, D.W., Calcium-mediated neurotoxicity: relationship to specific channel types and role in ischemic damage, Trends Neurosci., 11 (1988) 465-469.
6. Dawson, V.L., Dawson, T.M., London, E.D., Bredt, D.S. and Snyder, S.H., Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures, Proc. Natl. Acad. Sci. USA, 88 (1991) 6368-6371.
7. Ernfors, P., Ibanez, C.F., Ebendal, C., Olson, L. and Persson, H., Identification of cells in rat brain and peripheral tissues expressing mRNA for members of the nerve growth factor family., Neuron, 5 (1990) 511-526.
8. Garthwaite, G. and Garthwaite, J., Nitric oxide does not mediate acute glutamate neurotoxicity, nor is it neuroprotective, in rat brain slices, Neuropharmacol., 33 (1994) 1431-1438.
9. Ghosh, A., Carnahan, J. and Greenber, M.E., Requirement for BDNF in activity-dependent survival of cortical neurons, Science, 263 (1994) 1618-1623.
10. Hewett, S.J., Corbett, J.A., McDaniel, M.L. and Choi, D.W., Inhibition of nitric oxide formation does not protect murine cortical cell cultures from N-methyl-D-aspartate neurotoxicity, Brain Res., 625 (1994) 337-341.
11. Huang, Z., Huang, P.L., Panahian, N., Dalkara, T., Fishman, M.C. and Moskowitz, M.A., Effects of cerebral ischemia in mice deifficient in neuronal nitric oxide synthase, Science, 265 (1994) 1883-1885.
12. Izumi, Y., Benz, A.M., Clifford, D.B. and Zorumski, C.F., Nitric oxide inhibitors attenuate N-methyl-D-aspartate excitotoxicity in rat hippocampal slices, Neurosci. Lett., 135 (1992) 227-230.
13. Jackson, G.R., Apffel, L., Werrbach-Perez, K. and Perez-Polo, J.R., Role of nerve growth factors in oxidant-antioxidant balance and neuronal injury. I. Stimulation of hydrogen peroxide resistance, J. Neurosci. Res., 25 (1990) 360-368.
14. Klein, R., Nandrui, V., Jing, S., Lamballe, F., Tapely, P., Bryant, S., Cordon-Cardo, C., Jones, K.R., Reichardt, L. and Barbacid, M., The trkB tyrosine protein kinase is a receptor for brain-derived neurotrophic factor and neurotrophin-3, Cell, 66 (1991) 395-403.
15. Koh, J.Y., Gwag, B.J., Lobner, D. and Choi, D.W., Potentiated necrosis of cultured cortical neurons by neurotrophins, Science, 268 (1994) 573-575.
16. Lei, S.Z., Pan, Z.H., Aggarwal, S.K., Chen, H.S.V., Hartman, J., Sucher, N.J. and Lipton, S.A., Effect of nitric oxide production on the redox modulatory site of the NMDA receptor-channel complex, Neuron, 8 (1992) 2087-2099.
17. Lindholm, D., Dechant, G., Heisenberg, C.P. and Thoenen, H., Brain-derived neurotrophic factor is a survival factor for cultured rat cerebellar granule neurons and protects them against glutamate-induced neurotoxicity, Eur. J. Neurosci., 5 (1993) 1455-1464.
18. Lindvall, O., Ernfors, P., Bengzon, J., Kokaia, Z., Simith, M.L., Siesjo, B.K. and Persson, H., Differential regulation of mRNAs for nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 in the adult rat brain following cerebral ischemia and hypoglycemic coma, Proc. Natl. Acad. Sci. USA, 89 (1992) 648-652.
19. Lipton, S.A., Choi, Y.B., Pan, Z.H., Lei, S.Z., Vincent Chen, J.S., Sucher, N.J., Loscalzo, J., Singel, D.J. and Stamler, J.S., A redoxbased mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds, Nature, 364 (1993) 626-632.
20. Meldrum, B. and Garthwaite, J., Excitatory amino acid neurotoxicity and neurodegenerative disease, Trends Pharmacol. Sci., 11 (1990) 379-387.
21. Phillips, H.S., Hains, J.M., Armanini, M., Laramee, G.R., Johnson, S.A. and Winslow, J.W., BDNF mRNA is decreased in the hippocampus of individuals with Alzheimer's disease, Neuron, 7 (1991) 695-702.
22. Phillips, H.S., Hains, J.M., Laramee, G.R., Rosenthal, A. and Winslow, J.W., Widespread expression of BDNF but not NT3 by target areas of basal forebrain cholinergic neurons, Science, 250 (1990) 290-294.
23. Shimohama, S., Tamura, Y., Akaike, A., Tsukahara, T., Ohara, O., Watanabe, S. and Kimura, J., Brain-derived neurotrophic factor pretreatment exerts a partially protective effect against glutamate-induced neurotoxicity in cultured rat cortical neurons, Neurosci. Lett., 164 (1993) 55-58.
24. Soppet, D., Escandon, E., Maragos, J., Middlemas, D.S., Reid, S.W., Blair, J., Burton, L.E., Stanton, B.R., Kaplan, D.R., Hunter, T., Nikolics, K. and Parada, L.F., The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor, Cell, 65 (1991) 895-903.
25. Tamura, Y., Sato, Y., Akaike, A. and Shiomi, H., Mechanisms of cholecystokinin-induced protection of cultured cortical neurons against N-methyl-D-aspartate receptor-mediated glutamate cytotoxicity, Brain Res., 592 (1994) 317-325.
26. Thoenen, H., The changing scene of neurotrophic factors, Trends Neurosci., 14 (1991) 165-170.
27. Wong, E.H.F., Kemp, J.A., Priestley, T., Knight, A.R. and Woodruff, G.N., The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist, Proc. Natl. Acad. Sci. USA, 83 (1986) 7104-7108.
28. Zhang, Y., Tatsuo, T., Carney, J.M. and Mattoson, M.P., Basic FGF, NGF and IGF-II protect hippocampal and cortical neurons against iron-induced degeneration, J. Cereb. Blood Flow Metab., 13 (1993) 378-388.