Molecular mechanisms associated with Se-allylselenocysteine regulation of cell proliferation and apoptosis

Cancer Letters

Volumn 162, Issue 2, 2001, Pages 167-173

  Jiang, Weiqin ^a   Zhu, Zongjian ^a   Ganther, Howard E ^b   Ip, Clement ^c   Thompson, Henry J ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

Alkylselenocysteine; Apoptosis; Cell growth; Selenium

Indexed keywords

CYSTEINE DERIVATIVE; DNA; SELENIUM DERIVATIVE;

ANIMAL CELL; APOPTOSIS; ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; BREAST EPITHELIUM; CELL CYCLE; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; APOPTOSIS; CELL CYCLE PROTEINS; CELL DIVISION; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; GROWTH INHIBITORS; HYPERPLASIA; MAMMARY GLANDS, ANIMAL; MICE; ORGANOSELENIUM COMPOUNDS; PHOSPHORYLATION; RETINOBLASTOMA PROTEIN; SELENOCYSTEINE;

EID: 0035951705     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(00)00647-9     Document Type: Article

References (26)

1. Comparison of the effects of an organic and an inorganic form of selenium on a mammary carcinoma cell line
2. Selenium metabolism, selenoproteins and mechanisms of cancer prevention: Complexities with thioredoxin reductase
3. Lessons from basic research in selenium and cancer prevention
4. Current ideas on selenium as a chemopreventive agent
5. Selenium modulation of cell proliferation and cell cycle biomarkers in normal and premalignant cells of the rat mammary gland
6. Synthesis of novel Se-substituted selenocysteine derivatives as potential kidney selective prodrugs of biologically active selenol compounds: Evaluation of kinetics of beta-elimination reactions in rat renal cytosol
7. Comparison of selenium and sulfur analogs in cancer prevention
8. Chemoprevention of mammary cancer with Se-allylselenocysteine and other selenoamino acids in the rat
9. In vitro effects of Se-allylselnocysteine and Se-propylselenocysteine on cell growth. DNA integrity and apoptosis
10. Radiation-induced tumorigenesis in preneoplastic mouse mammary glands in vivo: Significance of P53 status and apoptosis
11. Dissociation of the genotoxic and growth inhibitory effects of selenium
12. Selenite induction of DNA strand breaks and apoptosis in mouse leukemic L1210 cells
13. Organic and inorganic selenium compounds inhibit mouse mammary cell growth in vitro by different cellular pathways
14. Inhibition of cdk2 kinase activity by methylselenocysteine in synchronized mouse mammary epithelial tumor cells
15. Effects of methylselenocysteine on PKC activity, cdk2 phosphorylation and gadd gene expression in synchronized mouse mammary epithelial tumor cells
16. Morphological and functional properties of TM preneoplastic mammary outgrowths
17. Differential effects of selenium on the growth of mouse mammary cells in vitro
18. Morphological and biochemical assays of apoptosis
19. Multiple functions of P27(Kip1) and its alterations in tumor cells: A review
20. The Pezcoller lecture: Cancer cell cycles revisited
21. C.D.K. inhibitors: Positive and negative regulators of G1-phase progression
22. Regulation of P53 in response to DNA damage
23. The role of P53 in tumour suppression: Lessons from mouse models
24. Involvement of P53 and P21 in cellular defects and tumorigenesis in Atm-/-mice
25. Density-dependent growth inhibition of fibroblasts ectopically expressing P27(kip1)