Effects of methylselenocysteine on PKC activity, cdk2 phosphorylation and gadd gene expression in synchronized mouse mammary epithelial tumor cells

Cancer Letters

Volumn 146, Issue 2, 1999, Pages 135-145

  Sinha, R ^a   Kiley, S C ^b   Lu, J X ^c   Thompson, H J ^c   Moraes, R ^a   Jaken, S ^d   Medina, D ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c UNIVERSITY OF COLORADO   (United States)

^d UNIVERSITY OF VERMONT   (United States)

Author keywords

cdk2; Gadd genes; Methylselenocysteine; Mouse mammary cell line; Protein kinase C

Indexed keywords

CYCLIN DEPENDENT KINASE; PROTEIN KINASE C; SELENOCYSTEINE;

ANIMAL CELL; APOPTOSIS; ARTICLE; BREAST CANCER; BREAST EPITHELIUM; CELL CYCLE; ENZYME ACTIVITY; GENE EXPRESSION; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING;

ANIMALS; ANTICARCINOGENIC AGENTS; ANTIGENS, DIFFERENTIATION; BLOTTING, WESTERN; CCAAT-ENHANCER-BINDING PROTEINS; CDC2-CDC28 KINASES; CELL CYCLE PROTEINS; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASES; CYSTEINE; DNA-BINDING PROTEINS; FEMALE; GENE EXPRESSION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; ISOENZYMES; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; ORGANOSELENIUM COMPOUNDS; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; THYMIDINE; TRANSCRIPTION FACTOR CHOP; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED;

EID: 0032741145     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(99)00250-5     Document Type: Article

References (44)

1. Ip C. The chemopreventive role of selenium in carcinogenesis. J. Am. Coll. Toxicol. 5:1986;7-20.
2. Ip C., El-Bayoumy K., Upadhyaya P., Ganther H., Vadhanvikit S., Thompson H.J. Comparative effect of inorganic and organic selenocyanate derivatives in mammary cancer chemoprevention. Carcinogenesis. 15:1994;187-192.
3. Medina D., Morrison D.G., Oborn C.J. Selenium retention and inhibition of cell growth in mouse mammary epithelial cell lines in vitro. Biol. Trace Element Res. 8:1985;19-35.
4. Chatterjee M., Banerjee M.R. Selenium-mediated dose inhibition of 7,12-dimethylbenzantracene-induced transformation of mammary cells in organ culture. Cancer Lett. 17:1982;187-195.
5. Ip C., Medina D. Current concept of selenium and mammary tumorigenesis. Medina D., Kidwell W., Heppner G., Anderson E.P. Cellular and Molecular Biology of Breast Cancer. 1987;479-494 Plenum Press, New York.
6. Lu J.X., Pei H.Y., Ip C., Lisk D.J., Ganther H., Thompson H.J. Effect of an aqueous extract of selenium-enriched garlic on in vitro markers and in vivo efficacy in cancer prevention. Carcinogenesis. 17:1996;1903-1907.
7. Sinha R., Medina D. Inhibition of cdk2 kinase activity by methylselenocysteine in synchronized mouse mammary epithelial tumor cells. Carcinogenesis. 18:1997;1541-1547.
8. Reddy B.S., Wynn T.T., El-Bayoumy K., Upadhyaya P., Fiala E., Rao C.V. Evaluation of organoselenium compounds for potential chemopreventive properties in colon cancer. Anticancer Res. 16:1996;1123-1127.
9. Stewart M.S., Davis R.L., Walsh L.P., Pence B.C. Induction of differentiation and apoptosis by sodium selenite in human colon carcinoma cells (HT29). Cancer Lett. 117:1997;35-40.
10. Yu S.Y., Zhu Y.J., Li W.G. Protective role of selenium against hepatitis B virus and primary liver cancer in Qidong. Biol. Trace Element Res. 56:1997;117-124.
11. Redman C., Xu M.J., Peng Y.M., Scott J.A., Payne C., Clark L.C., Nelson M.A. Involvement of polyamines in selenomethionine induced apoptosis and mitotic alterations in human tumor cells. Carcinogenesis. 18:1997;1195-1202.
12. El-Bayoumy K. The role of selenium in cancer prevention. DeVita V.T., Hellman S., Rosenberg S.S. Cancer Principles and Practice of Oncology. 4th ed :1991;1-15 J.B. Lippincott Co, Philadelphia.
13. Yang G., Chen J., Wen Z., Ge K., Zhu L. The role of selenium in Keshan disease. Adv. Nutr. Res. 6:1984;203-231.
14. Blot W.J., Li J.-Y., Taylor P.R., Guo W. Nutrition intervention trials in Linxian, China: supplementation with specific vitamin/mineral combinations, cancer incidence and disease-specific mortality in the general population. J. Natl. Cancer Inst. 85:1993;1483-1492.
15. Clark L.C., Combs G.F., Turnbull W.B. Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin: a randomized controlled trial. J. Am. Med. Assoc. 276:1996;1957-1963.
16. Ip C., Ganther H.E. Activity of methylated forms of selenium in cancer prevention. Cancer Res. 50:1990;1206-1211.
17. Ip C., Lisk D.J. Characterization of tissue selenium profiles and anticarcinogenic responses in rats fed natural sources of selenium-rich products. Carcinogenesis. 15:1994;573-576.
18. Ip C., Hayes C., Budnick R.M., Ganther H.E. Chemical form of selenium, critical metabolites and cancer prevention. Cancer Res. 51:1991;595-600.
19. Ip C., Ganther H.E. Relationship between chemical form of selenium and anticarcinogenic activity. Wattenberg L., Lipkin M., Boone C., Kellog C. Cancer Chemoprevention. 1992;479-488 CRC Press, Boca Raton, FL.
20. Ip C., Lisk D.J., Stoewsand G.S. Mammary cancer prevention by regular garlic and selenium-enriched garlic. Nutr. Cancer. 17:1992;279-286.
21. Ip C., Lisk D.J. Efficacy of cancer prevention by high-selenium garlic is primarily dependent on the action of selenium. Carcinogenesis. 16:1995;2649-2652.
22. Vadhanavikit S., Ip C., Ganther H.E. Metabolites of sodium selenite and methylated selenium compounds administered at cancer chemoprevention levels in the rat. Xenobiotica. 23:1993;731-745.
23. Thompson H.J., Wilson A., Lu J.X., Singh M., Jiang C., Upadhyaya P., El-Bayoumy K., Ip C. Comparison of the effects of an organic and inorganic form of selenium on mammary carcinoma cell line. Carcinogenesis. 15:1994;183-186.
24. Sinha R., Said T.K., Medina D. Organic and inorganic selenium compounds inhibit mouse mammary cell growth in vitro by different cellular pathways. Cancer Lett. 107:1996;277-284.
25. Kaek M., Lu J.X., Strange R., Ip C., Ganther H.E., Thompson H.J. Differential induction of growth arrest inducible genes by selenium compounds. Biochem. Pharmacol. 53:1997;921-926.
26. Chen H.C. Inhibition of the protein kinase C-α gene over expression in rat preneoplastic liver by selenium. Chung-Hua Chung Liu Tsa Chih (Chin. J. Oncol.). 15:1993;279-281.
27. 2+-dependent isoenzymes of protein kinase C. Arch. Biochem. Biophys. 348:1997;25-36.
28. Foiles P.G., Fujiki H., Sugaruma M., Okabe S., Yatsunami J., Miglietta L.M., Upadhyaya P., El-Bayoumy K., Ronai Z. Inhibition of PKC and PKA by chemopreventive organoselenium compounds. Int. J. Oncol. 7:1995;685-690.
29. Yan L., Frenkel G.D. Inhibition of cell attachment by selenite. Cancer Res. 52:1992;5803-5807.
30. Jerry J.D., Butel J.S., Medina D. p53 mutations in COMMA-D cells in vitro. Cell. Dev. Biol. 30:1994;87-89.
31. Gopalakrishna R., Barsky S.H., Thomas T.P., Anderson W.B. Factors influencing chelator-stable, detergent-extractable, phorbol diester-induced membrane association of protein kinase C. J. Biol. Chem. 261:1986;16348-16445.
32. Gopalakrishna R., Chen Z.H., Gundimeda U., Wilson J.C., Anderson W.B. Rapid filtration assays for protein kinase C activity and phorbol ester binding using multiwell plates with fitted filtration discs. Anal. Biochem. 206:1992;24-35.
33. Smith P.K., Krohn R.I., Hermanson G.T., Mallia A.K., Gartner F.H., Provenzano M.D., Fujimoto E.K., Goeke N.M., Olson B.K., Klenk D.C., Measurement D.C. of protein using bicinchoninic acid. Anal. Biochem. 150:1985;76-85.
34. Schaap D., Parker P.J., Bristol A., Kriz R., Knopf J. Unique substrate specificity and regulatory properties of PKC-ε: a rationale for diversity. FEBS Lett. 243:1989;351-357.
35. Ways D.K., Cook P.P., Webster C., Parker P.J. Effect of phorbol esters on protein kinase C ζ J. Biol. Chem. 267:1992;4799-4805.
36. Leach K.L., Powers E.A., McGuire J.C., Dong L., Kiley S.C., Jaken S. Monoclonal antibodies specific for type 3 protein kinase C recognized distinct domains of protein kinase C and inhibit in vitro functional activity. J. Biol. Chem. 263:1988;13223-13230.
37. Benbassat H., Rosenbaummitrani S., Hartzstark Z., Shlomai Z., Kleinbergerdoron N., Gazit A., Plowman G., Levitzki R., Tsvieli R., Levitzki A. Inhibitors of epidermal growth factor receptor kinase and of cyclin-dependent kinase 2 activation induce growth arrest, differentiation, and apoptosis of human papilloma virus 16-immortalized human keratinocytes. Cancer Res. 57:1997;3741-3750.
38. Meikrantz W., Schlegel R. Apoptosis and the cell cycle. J. Cell. Biochem. 19A. 1995;184.
39. Kiley S.C., Welsh J., Narvez C.J., Jaken S. Protein kinase C isozymes and substrates in mammary carcinogenesis. J. Mamm. Gland Biol. Neoplasia. 1:1996;177-187.
40. 2+-dependent protein kinase (protein kinase C) system from human leukemic cells. Cancer Res. 46:1986;3684-3787.
41. Asiedu C., Biggs J., Lilly M., Kraft S.A. Inhibition of leukemic cell growth by the protein kinase C activator Bryostatin 1 correlates with the dephosphorylation of cyclin-dependent kinase 2. Cancer Res. 55:1995;3716-3720.
42. Hamada K., Takuwa N., Zhou W., Kumada M., Takuwa Y. Protein kinase C inhibits CAK-cdk2 kinase-dependent kinase cascade and G1/S cell cycle progression in human diploid fibroblasts. Biochim. Biophys. Acta. 1310:1996;149-156.
43. Kawakami K., Futami H., Takahara J., Yamaguchi K. UCN-01, 7-hydroxyl-staurosporine, inhibits kinase activity of cyclin-dependent kinases and reduces the phosphorylation of the retinoblastoma susceptibility gene product in A549 human lung cancer cell line. Biochem. Biophys. Res. Commun. 219:1996;778-783.
44. Wang Q., Worland P.J., Clark J.L., Carlson B.A., Sausville E.A. Apoptosis in 7-hydroxystaurosporine-treated T lymphoblasts correlates with activation of cyclin-dependent kinases 1 and 2. Cell Growth Diff. 6:1995;927-936.