Effect of deficiency of the double-stranded RNA-dependent protein kinase, PKR, on antiviral resistance in the presence or absence of ribonuclease L: HSV-1 replication is particularly sensitive to deficiency of the major IFN-mediated enzymes

Journal of Interferon and Cytokine Research

Volumn 20, Issue 7, 2000, Pages 653-659

  Khabar, Khalid S A ^a,b   Dhalla, Mohammed ^a   Siddiqui, Yunus ^a   Zhou, Amin ^b   Al Ahdal, Mohammed N ^a   Der, Sandy D ^b   Silverman, Robert H ^b   Williams, Bryan R G ^b  

^a KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

^b LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2',5' OLIGOADENYLATE SYNTHETASE; DOUBLE STRANDED RNA; GAMMA INTERFERON; PROTEIN KINASE; RIBONUCLEASE;

ANIMAL CELL; ANTIBIOTIC RESISTANCE; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; ENCEPHALOMYOCARDITIS VIRUS; GENE DISRUPTION; HERPES SIMPLEX VIRUS 1; HOST RESISTANCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; VIRUS INFECTION; VIRUS REPLICATION;

ANIMALS; CROSSES, GENETIC; EIF-2 KINASE; EMBRYO; ENCEPHALOMYOCARDITIS VIRUS; ENDORIBONUCLEASES; FIBROBLASTS; HERPESVIRUS 1, HUMAN; IMMUNITY, NATURAL; INTERFERON-ALPHA; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; MICE, KNOCKOUT; VESICULAR STOMATITIS-INDIANA VIRUS; VIRAL PROTEINS; VIRUS REPLICATION;

ANIMALIA; DNA VIRUSES; ENCEPHALOMYOCARDITIS VIRUS; HERPES; HUMAN HERPESVIRUS 1; MYXOVIRUS; RNA VIRUSES; VESICULAR STOMATITIS VIRUS;

EID: 0033911420     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: 10.1089/107999000414835     Document Type: Article

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