Novel Role of Phosphatidylinositol 3-Kinase in CD28-mediated Costimulation

Journal of Biological Chemistry

Volumn 276, Issue 12, 2001, Pages 9003-9008

  Harada, Yohsuke ^a   Tanabe, Eri ^a   Watanabe, Ryosuke ^a   Weiss, Bonnie D ^b   Matsumoto, Akira ^a   Ariga, Hiroyoshi ^c   Koiwai, Osamu ^a   Fukui, Yasuhisa ^d   Kubo, Masato ^a   June, Carl H ^e   Abe, Ryo ^a  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

^b NAVAL MEDICAL RESEARCH CENTER   (United States)

^c HOKKAIDO UNIVERSITY   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; CELLS; ENZYME INHIBITION; ENZYME KINETICS; GENETIC ENGINEERING; MUTAGENESIS;

GENE TRANSCRIPTIONS;

BIOCHEMISTRY;

CD28 ANTIGEN; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; INTERLEUKIN 2; MEMBRANE RECEPTOR; MUTANT PROTEIN; PEPTIDE DERIVATIVE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; TYROSYLMETHIONYLASPARAGINYLMETHIONINE; UNCLASSIFIED DRUG; 2 MORPHOLINO 8 PHENYLCHROMONE; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; CHROMONE DERIVATIVE; ENZYME INHIBITOR; MORPHOLINE DERIVATIVE;

ARTICLE; BINDING SITE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DELETION MUTANT; ENZYME ACTIVITY; ENZYME BINDING; GENE ACTIVATION; GENE EXPRESSION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LYMPHOCYTE FUNCTION; MOUSE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; AMINO ACID SEQUENCE; CHEMISTRY; DRUG ANTAGONISM; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; MOLECULAR GENETICS; PHYSIOLOGY; SEQUENCE HOMOLOGY; T LYMPHOCYTE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANTIGENS, CD28; CHROMONES; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-2; JURKAT CELLS; LYMPHOCYTE ACTIVATION; MOLECULAR SEQUENCE DATA; MORPHOLINES; PROMOTER REGIONS (GENETICS); SEQUENCE HOMOLOGY, AMINO ACID; T-LYMPHOCYTES;

EID: 0035937791     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M005051200     Document Type: Article

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