Mapping of 5-HT2A receptors and their mRNA in monkey brain: [3H]MDL100,907 autoradiography and in situ hybridization studies

Journal of Comparative Neurology

Volumn 429, Issue 4, 2001, Pages 571-589

  López Giménez, Juan F ^a   Vilaró, M Teresa ^a   Palacios, José M ^a   Mengod, Guadalupe ^a  

^a INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

Author keywords

3H ketanserin; Atypical antipsychotics; Primate brain; Serotonin

Indexed keywords

ALPHA (2,3 DIMETHOXYPHENYL) 1 [2 (4 FLUOROPHENYL)ETHYL] 4 PIPERIDINEMETHANOL; BRAIN RECEPTOR; KETANSERIN; MESSENGER RNA; SEROTONIN 2A RECEPTOR; TRITIUM; FLUOROBENZENE; PIPERIDINE DERIVATIVE; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR;

ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING SITE; BRAIN MAPPING; BRAIN REGION; CHOROID PLEXUS; FEMALE; IN SITU HYBRIDIZATION; MALE; MONKEY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RECEPTOR DENSITY; SIGNAL PROCESSING; SPECIES DIFFERENCE; STRIATE CORTEX; TISSUE DISTRIBUTION; ANIMAL; BRAIN; HUMAN; MACACA; METABOLISM; METHODOLOGY; PHYSIOLOGY;

ANIMALS; AUTORADIOGRAPHY; BRAIN; BRAIN MAPPING; FEMALE; FLUOROBENZENES; HUMANS; IN SITU HYBRIDIZATION; KETANSERIN; MACACA FASCICULARIS; MACACA MULATTA; MALE; PIPERIDINES; RECEPTOR, SEROTONIN, 5-HT2A; RECEPTORS, SEROTONIN; RNA, MESSENGER; SEROTONIN ANTAGONISTS;

EID: 0035931138     PISSN: 00219967     EISSN: None     Source Type: Journal    
DOI: 10.1002/1096-9861(20010122)429:4<571::AID-CNE5>3.0.CO;2-X     Document Type: Article

References (72)

1. Serotonin induces excitatory postsynaptic potentials in apical dendrites of neocortical pyramidal cells
2. 2A receptors, increases EPSCs in layer V pyramidal cells of prefrontal cortex by an asynchronous mode of glutamate release
3. Autoradiographic demonstration of increased serotonin 5-HT2 and beta-adrenergic receptor binding sites in the brain of suicide victims
4. Serotonin2 (5-HT2) receptor binding in the frontal cortex of schizophrenic patients
5. A review of central 5-HT receptors and their function
6. 5-HT2 receptor subtypes: A family re-united?
7. Neurotransmitter receptors in frontal cortex of schizophrenics
8. Adrenergic and serotonergic receptors in aged monkey neocortex
9. Correspondence between 5-HT2 receptors and serotonergic axons in rat neocortex
10. 2A receptor mRNA in human brain
11. 2A receptor mRNAs and binding site densities are differentially altered in schizophrenia
12. Topography of cholinergic and substance P pathways in the habenulo-interpeduncular system of the rat: An immunocytochemical and microchemical approach
13. 2A receptor in the central nervous system of adult rat
14. 2A receptors in schizophrenia
15. Serotonin2 receptors and the serotonin transporter in the schizophrenic brain
16. 5 HT2 receptors in dementia of Alzheimer type: A quantitative autoradiographic study of frontal cortex and hippocampus
17. Serotonergie modulation of striatal dopamine measured with positron emission tomography (PET) and in vivo microdialysis
18. 2A receptor gene with suicidal ideation in major depressive disorder
19. 2 receptor antagonist
20. 2A) receptor gene: Identification of two naturally occurring receptor variants and association analysis in schizophrenia
21. Parcellation of the frontal cortex of the New World monkey Callithrix jacchus by eight neurotransmitter-binding sites
22. Overlap of dopaminergic, adrenergic, and serotoninergic receptors and complementarity of their subtypes in primate prefrontal cortex
23. Autoradiographic analysis of [3H]ketanserin binding in the human brain postmortem: Effect of suicide
24. Ovarian steroid effects on serotonin 1A, 2A and 2C receptor mRNA in macaque hypothalamus
25. 2A receptor in rat cerebral cortex and olfactory system revealed by immunohistochemistry using two antibodies raised in rabbit and chicken
26. Differential changes in serotonin 5-HT1A and 5-HT2 receptor binding in patients with chronic schizophrenia
27. International Union of Pharmacology classification of receptors for 5- hydroxytryptamine (serotonin)
28. 5-HT uptake sites and 5-HT2 receptors in brain of antidepressant-free suicide victims/depressives: Increase in 5-HT2 sites in cortex and amygdala
29. Effect of antipsychotic drugs on extracellular serotonin levels in rat medial prefrontal cortex and nucleus accumbens
30. 2A receptor: An immunohistochemical demonstration
31. 2A receptor gene and schizophrenia
32. 2A receptors with carbon-11-MDL 100,907
33. 2A serotonin receptors in the primate cerebral cortex: Possible site of action of hallucinogenic and antipsychotic drugs in pyramidal cell apical dendrites
34. 2A receptor ligand
35. A "direct coloring" thiocholine method for cholinesterases
36. 2A antagonist with a favorable CNS safety profile
37. Receptor binding profile of R 41 468, a novel antagonist at 5-HT2 receptors
38. Distribution of major neurotransmitter receptors in the motor and somatosensory cortex of the rhesus monkey
39. Quantitative autoradiographic mapping of serotonin 5-HT1 and 5-HT2 receptors and uptake sites in the neocortex of the rhesus monkey
40. 2A receptors by autoradiography with [3H]MDL 100,907
41. 2A serotouin receptors selectively in primate brain
42. 2A receptors: Autoradiographic visualization with [3H]MDL100,907, [125I](+/-)DOI and [3H]ketanserin
43. Brain 5-HT2 receptors in suicide victims: Violence of death, depression and effects of antidepressant treatment
44. Increased serotonin2 and beta-adrenergic receptor binding in the frontal cortices of suicide victims
45. 2A receptor antagonist
46. 2A receptors in late-life neuropsychiatric disorders
47. The role of serotonin in antipsychotic drug action
48. Localization of the mRNA for the 5-HT2 receptor by in situ hybridization histochemistry: Correlation with the distribution of receptor sites
49. 5-HT receptors in mammalian brain: Receptor autoradiography and in situ hybridization studies of new ligands and newly identified receptors
50. Immunocytochemical local ization and description of neurons expressing serotouin2 receptors in the rat brain
51. Electrophysiological, biochemical and behavioral evidence for 5-HT2 and 5-HT3 mediated control of dopaminergic function
52. Comparative anatomical distribution of serotonin 1A, 1D alpha, and 2A receptor mRNAs in human brain postmortem
53. Quantitative autoradiographic mapping of serotonin receptors in the rat brain: II. Serotonin-2 receptors
54. Serotonin receptors in the human brain: IV. Autoradiographic mapping of serotonin-2 receptors
55. Multiple serotonin receptors: Differential binding of [3H]5-hydroxytryptamine, [3H]lysergic acid die ethylamide and [3H]spiroperidol
56. 2C receptors
57. Quantitative autoradiography of major neurotransmitter receptors in the monkey striate and extrastriate cortex
58. Reduced binding of [3H]ketanserin to cortical 5-ht2 receptors in senile dementia of the Alzheimer type
59. 2A receptors in mice lacking the serotonin transporter
60. The selective 5-HT2A receptor antagonist, MDL 100,907, increases dopamine effiux in the prefrontal cortex of the rat
61. 2A receptor blockade
62. 5-HT2 receptors exert a state-dependent regulation of dopaminergic function: Studies with MDL 100,907 and the amphetamine analogue, 3,4-methylenedioxymethamphetamine
63. Blockade of striatal 5-hydroxytryptamine2 receptors reduces the increase in extracellular concentrations of dopamine produced by the amphetamine analogue 3,4-methylenedioxymethamphetamine
64. 2A receptors in antipsychotic activity
65. Blockade of the discriminative stimulus effects of DOI by MDL 100,907 and the 'atypical' antipsychotics, clozapine and risperidone
66. (1-(2,5-dimethoxy-4 iodophenyl)-2-aminopropane)-induced head-twitches in the rat are mediated by 5-hydroxytryptamine (5-HT) 2A receptors: Modulation by novel 5-HT2A/2C antagonists, D1 antagonists and 5-HT1A agonists
67. Characterization of the 5-HT2 receptor antagonist MDL 100907 as a putative atypical antipsychotic: Behavioral, electrophysiological and neurochemical studies
68. 1A receptors using a radiolabeled antagonist: Comparison with agouist radioligand
69. Selectivity of action of typical and atypical anti-psychotic drugs as antagonists of the behavioral effects of 1-[2,5-dimethoxy-4-iodophenyl]-2-aminopropane (DOI)
70. 2C polymorphism of the 5- hydroxytryptamine type 2a-receptor gene. European Multicentre Association Study of Schizophrenia (EMASS) Group
71. Comparative localization of serotonin1A, 1C, and 2 receptor subtype mR-NAs in rat brain