Short-range and long-range guidance by Slit and its robo receptors: Robo and Robo2 play distinct roles in midline guidance

Neuron

Volumn 28, Issue 3, 2000, Pages 753-766

  Simpson, Julie H ^a   Kidd, Thomas ^a   Bland, Kimberly S ^a   Goodman, Corey S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; PROTEIN ROBO2; PROTEIN ROBO3; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; DIMERIZATION; DROSOPHILA; GENE EXPRESSION; GROWTH CONE; HETEROZYGOSITY; MUTANT; NERVE GROWTH; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SEQUENCE ANALYSIS;

DROSOPHILA;

EID: 0034525272     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(00)00151-3     Document Type: Article

References (28)

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3. Repulsive axon guidance: Abelson and Enabled play opposing roles downstream of the roundabout receptor
4. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
5. Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance
6. Identification and cloning of ELF-1, a developmentally expressed ligand for the Mek4 and Sek receptor tyrosine kinases
7. Embryonic development of the Drosophila central nervous system
8. Guidance cues of the Drosophila CNS midline: Identification and characterization of two Drosophila Netrin/UNC-6 homologs
9. Targeted neuronal ablation: The role of pioneer neurons in guidance and fasciculation in the CNS of Drosophila
10. Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors
11. Dosage-sensitive and complementary functions of roundabout and commissureless control axon crossing of the CNS midline
12. Slit is the midline repellent for the Robo receptor in Drosophila
13. Genetic analysis of Fasciclin II in Drosophila: Defasciculation, refasciculation, and altered fasciculation
14. The cell adhesion molecule, connectin, and the development of the Drosophila neuromuscular system
15. Genetic analysis of Netrin genes in Drosophila: Netrins guide CNS commissural axons and peripheral motor axons
16. Connectin: A homophilic cell adhesion molecule expressed on a subset of muscles and the motoneurons that innervate them in Drosophila
17. Imaging neuronal subsets and other cell types in whole mount Drosophila embryos and larvae using antibody probes
18. A modular misexpression screen in Drosophila detecting tissue-specific phenotypes
19. Slit: An EGF-homologous locus of D. melanogaster involved in the development of the embryonic central nervous system
20. Slit: An extracellular protein necessary for development of midline glia and commissural axon pathways contains both EGF and LRR domains
21. A Drosophila complementary DNA resource
22. Mutations affecting growth cone guidance in Drosophila: Genes necessary for guidance toward or away from the midline
23. The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6
24. Short-range and long-range guidance by Slit and its Robo receptors: A combinatorial code of Robo receptors controls lateral position
25. Commissureless controls growth cone guidance across the CNS midline in Drosophila and encodes a novel membrane protein
26. The molecular biology of axon guidance
27. Cloning and functional studies of a novel gene aberrantly expressed in RB-deficient embryos
28. The conserved immunoglobulin superfamily member SAX-3/Robo directs multiple aspects of axon guidance in C. elegans