Interactions of Drosophila Cbl with epidermal growth factor receptors and role of Cbl in R7 photoreceptor cell development

Molecular and Cellular Biology

Volumn 17, Issue 4, 1997, Pages 2217-2225

  Meisner, Herman ^a   Daga, Andrea ^b   Buxton, Joanne ^a   Fernández, Belén ^a   Chawla, Anil ^a   Banerjee, Utpal ^b   Czech, Michael P ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; EPIDERMAL GROWTH FACTOR RECEPTOR; GENE PRODUCT; ONCOPROTEIN; PROLINE; PROTEIN TYROSINE KINASE;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CAENORHABDITIS ELEGANS; DROSOPHILA; MOLECULAR CLONING; MONKEY; NONHUMAN; PHOTORECEPTOR CELL; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTO ONCOGENE; SEQUENCE HOMOLOGY;

ANIMALIA; CAENORHABDITIS ELEGANS; DROSOPHILA MELANOGASTER; MELANOGASTER;

EID: 0030978136     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.17.4.2217     Document Type: Article

References (36)

1. Andoniou, C., C. Thien, and W. Langdon. 1994. Tumour induction by activated abl involves tyrosine phosphorylation of the product of the cbl oncogene. EMBO J. 13:4515-4523.
2. Basler, K., B. Christen, and E. Hafen. 1991. Ligand-independent activation of the sevenless receptor tyrosine kinase changes the fate of cells in the developing Drosophila eye. Cell 64:1069-1081.
3. Blake, T., K. Heath, and W. Langdon. 1993. The truncation that generated the v-cbl oncogene reveals an ability for nuclear transport, DNA binding and acute transformation. EMBO J. 12:2017-2026.
4. Blake, T., M. Shapiro, H. Morse, and W. Langdon. 1991. The sequences of the human and mouse c-cbl proto-oncogenes show v-cbl was generated by a large truncation encompassing a proline-rich domain and a leucine zipper-like motif. Oncogene 6:653-657.
5. Bowtell, D., and W. Langdon. 1995. The protein product of the c-cbl oncogene rapidly complexes with the EGF receptor and is tyrosine phosphorylated following EGF stimulation. Oncogene 11:1561-1567.
6. Buday, L., A. Khwaja, S. Sipeki, A. Farago, and J. Downward. 1996. Interactions of Cbl with two adaptor proteins, Grb2 and Crk, upon T cell activation. J. Biol. Chem. 271:6159-6163.
7. Daga, A., and U. Banerjee. 1994. Resolving the Sevenless pathway using sensitized genetic backgrounds. Cell. Mol. Biol. Res. 40:245-251.
8. deJong, R., J. ten Hoeve, N. Heisterkamp, and J. Groffen. 1995. Crk1 is complexed with tyrosine-phosphorylated Cbl in Ph-positive leukemia. J. Biol. Chem. 270:21468-21471.
9. Donovan, J., R. Wange, W. Langdon, and L. Samelson. 1994. The protein product of the c-cbl protooncogene is the 120-kDa tyrosine-phosphorylated protein in Jurkat cells activated via the T cell antigen receptor. J. Biol. Chem. 169:22921-22924.
10. Freeman, R. 1996. Reiterative use of the EGF receptor triggers differentiation of all cell types in the Drosophila eye. Cell 87:651-660.
11. Fukazawa, T., S. Miyake, V. Band, and H. Band. 1996. Tyrosine phosphorylation of Cbl upon epidermal growth factor (EGF) stimulation and its association with EGF receptor and downstream signaling proteins. J. Biol. Chem. 271:14554-14559.
12. Fukazawa, T., K. Reedquist, T. Trub, S. Soltoff, G. Panchamoorthy, B. Druker, L. Cantley, S. Shoelson, and H. Band. 1995. The SH3 domain-binding T cell tyrosyl phosphoprotein p120. Demonstration of its identity with the c-cbl protooncogene product and in vivo complexes with Fyn, Grb2, and phosphatidylinositol 3-kinase. J. Biol. Chem. 270:19141-19150.
13. Galisteo, M., I. Dikic, A. Batzer, W. Langdon, and J. Schlessinger. 1995. Tyrosine phosphorylation of the c-cbl proto-oncogene product and association with epidermal growth factor (EGF) receptor upon EGF stimulation. J. Biol. Chem. 270:20242-20245.
14. Hartley, D., H. Meisner, and S. Corvera. 1995. Specific association of the b isoform of the p85 subunit of phosphatidylinositol-3-kinase with the protooncogene c-cbl. J. Biol. Chem. 270:18260-18263.
15. Honegger, A., T. Dull, S. Felder, E. van Obberghen, F. Bellot, D. Szapary, A. Schmidt, A. Ullrich, and J. Schlessinger. 1987. Point mutation at the ATP binding site of EGF receptor abolishes protein-tyrosine kinase activity and alters cellular routing. Cell 51:199-209.
16. Lai, W., P. Cameron, J. Doherty, B. Posner, and J. Bergeron. 1989. Ligand-mediated autophosphorylation activity of the epidermal growth factor receptor during internalization. J. Cell Biol. 109:2751-2760.
17. Langdon, W., J. Hartley, S. Klinken, S. Ruscetti, and H. Morse. 1989. v-cbl, an oncogene from a dual recombinant murine retrovirus that induces early B-lineage lymphomas. Proc. Natl. Acad. Sci. USA 91:9665-9669.
18. Lee, J., G. D. Jongeward, and P. Sternberg. 1994. unc-101 a gene required for many aspects of C. elegans development and behavior, encodes a clathrin-associated protein. Genes Dev. 8:60-73.
19. Levkowitz, G., L. Klapper, E. Tzahar, A. Freywald, M. Sela, and Y. Yarden. 1996. Coupling of the c-Cbl protooncogene product to ErbB-1/EGF-receptor but not to other ErbB proteins. Oncogene 12:1117-1127.
20. Lupher, M., K. Reedquist, S. Miyake, W. Langdon, and H. Band. 1996. A novel phosphotyrosine-binding domain in the N-terminal transforming region of Cbl interacts directly and selectively with ZAP-70 in T cells. J. Biol. Chem. 271:24063-24068.
21. Meisner, H., B. Conway, D. Hartley, and M. P. Czech. 1995. Interactions of Cbl with Grb2 and phosphatidylinositol 3′-kinase in activated Jurkat cells. Mol. Cell. Biol. 15:3571-3578.
22. Meisner, H., and M. P. Czech. 1995. Coupling of the proto-oncogene product of c-Cbl to the EGF receptor. J. Biol. Chem. 270:25332-25335.
23. Odai, H., K. Sasaki, A. Iwamatsu, Y. Hanazono, T. Tanaka, K. Mitani, Y. Yazaki, and H. Hirai. 1995. The proto-oncogene product c-Cbl becomes tyrosine phosphorylated by stimulation with GM-CSF1 or Epo and constitutively binds to the SH3 domain of Grb2/Ash in human hematopoietic cells. J. Biol. Chem. 270:10800-10805.
24. Olivier, J., T. Taabe, M. Henkemeyer, B. Dickson, G. Mbamalu, B. Margolis, J. Schlessinger, E. Hafen, and T. Pawson. 1993. A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange, Sos. Cell 73:179-191.
25. cbl is a major substrate of tyrosine phosphorylation upon B cell antigen receptor stimulation and interacts in vivo with Fyn and Syk tyrosine kinases, Grb2 and She adapters, and the p85 subunit of phosphatidylinositol 3-kinase. J. Biol. Chem. 271:3187-3194.
26. Reedquist, K., T. Fukazawa, B. Druker, G. Panchamoorthy, S. Shoelson, and H. Band. 1994. Rapid T-cell receptor-mediated tyrosine phosphorylation of p120, an Fyn/Lck Src homology 3 domain-binding protein. Proc. Natl. Acad. Sci. USA 91:4133-4139.
27. Reichman-Fried, M., B. Dickson, E. Hafen, and B.-Z. Shilo. 1994. Elucidation of the role of breathless, a Drosophila FGF receptor homolog, in tracheal cell migration. Genes Dev. 8:428-439.
28. Rivero-Lezcano, O., J. Sameshima, A. Marcilla, and K. Robbins. 1994. Physical association between src homology 3 elements and the protein product of the c-cbl proto-oncogene. J. Biol. Chem. 269:17363-17366.
29. Rogge, R., R. Cagan, A. Majumdar, T. Dulaney, and U. Banerjee. 1992. Neuronal development in the Drosophila retina: the sextra gene defines an inhibitory component in the developmental pathway of R7 photoreceptor cells. Proc. Natl. Acad. Sci. USA 89:5271-5275.
30. cbl is a cytosolic adapter protein that associates with phosphoinositide 3-kinase in response to epidermal growth factor in PC12 and other cells. J. Biol. Chem. 271:563-567.
31. Sorkin, A., and C. Waters. 1493. Endocytosis of growth factor receptors. Bioessays 15:375-382.
32. Tanaka, L. Neff, R. Baron, and J. Levy. 1995. Tyrosine phosphorylation and translocation of the c-Cbl protein after activation of tyrosinc kinase signaling pathways. J. Biol. Chem. 270:14347-14351.
33. Tsygankov, A., S. Mahajan, J. Fincke, and J. Bolen. 1996. Specific association of tyrosine-phosphorylated c-Cbl with Fyn tyrosine kinase in T cells. J. Biol. Chem. 271:27130-27137.
34. Tyers, M., G. Tokiwa, R. Nash, and B. Futcher. 1992. The Cln3-Cdc28 kinase complex of S. cerevisiae is regulated by proteolysis and phosphorylation. EMBO J. 11:1773-1784.
35. Yoon, C., J. Lee, G. Jongeward, and P. Sternberg. 1995. Similarity of sli-1, a regulator of vulval development in C. elegans, to the mammalian protooncogene c-cbl. Science 269:1102-1105.
36. Zipursky, S. L., and G. M. Rubin. 1994. Determination of neuronal cell fate: lessons from the R7 neuron of Drosophila. Annu. Rev. Neurosci. 17:373-397.