메뉴 건너뛰기




Volumn 8, Issue 4, 1997, Pages 359-379

The Cbl family of signal transduction molecules

Author keywords

Negative regulation; Oncogenesis; Protein tyrosine kinase; Receptor; Scaffold protein

Indexed keywords

ADAPTOR PROTEIN; MUTANT PROTEIN; PROTEIN TYROSINE KINASE;

EID: 0031394111     PISSN: 08939675     EISSN: None     Source Type: Journal    
DOI: 10.1615/critrevoncog.v8.i4.50     Document Type: Review
Times cited : (61)

References (109)
  • 1
    • 12044256844 scopus 로고
    • Tumor induction by activated abl involves tyrosine phosphorylation of the product of the cbl oncogene
    • Andoniou, C. E., C. B. F Thien, and W. Y. Langdon: Tumor induction by activated abl involves tyrosine phosphorylation of the product of the cbl oncogene. EMBO J., 13:4515-4523 (1994).
    • (1994) EMBO J. , vol.13 , pp. 4515-4523
    • Andoniou, C.E.1    Thien, C.B.F.2    Langdon, W.Y.3
  • 2
    • 0029946242 scopus 로고    scopus 로고
    • The two major sites of cbl tyrosine phosphorylation in abl-transformed cells select the crkL SH2 domain
    • Andoniou, C. E., C. B. F. Thien, and W. Y. Langdon: The two major sites of cbl tyrosine phosphorylation in abl-transformed cells select the crkL SH2 domain. Oncogene, 12:1981-1989 (1996).
    • (1996) Oncogene , vol.12 , pp. 1981-1989
    • Andoniou, C.E.1    Thien, C.B.F.2    Langdon, W.Y.3
  • 3
    • 0025605344 scopus 로고
    • The let-23 gene necessary for Caenorhabditis elegans vulval induction encodes a tyrosine kinase of the EGF receptor subfamily
    • Aroian, R. V., M. Koga, J. E. Mendel, Y. Ohshima, and P. W. Sternberg: The let-23 gene necessary for Caenorhabditis elegans vulval induction encodes a tyrosine kinase of the EGF receptor subfamily. Nature, 348:693-699 (1990).
    • (1990) Nature , vol.348 , pp. 693-699
    • Aroian, R.V.1    Koga, M.2    Mendel, J.E.3    Ohshima, Y.4    Sternberg, P.W.5
  • 4
    • 0030969634 scopus 로고    scopus 로고
    • Erythropoietin and interleukin-3 activate tyrosine phosphorylation of Cbl and association with Crk adaptor proteins
    • Barber, D. L., D. W. Mason, T. Fukazawa, K. Reedquist, B. Druker, H. Band, and A. D. D' Andrea: Erythropoietin and interleukin-3 activate tyrosine phosphorylation of Cbl and association with Crk adaptor proteins. Blood, 89:3166-3174 (1997).
    • (1997) Blood , vol.89 , pp. 3166-3174
    • Barber, D.L.1    Mason, D.W.2    Fukazawa, T.3    Reedquist, K.4    Druker, B.5    Band, H.6    D' Andrea, A.D.7
  • 5
    • 0025819499 scopus 로고
    • The sequences of the human and mouse c-Cbl protooncogenes show v-Cbl was generated by a large truncation encompassing a proline-rich domain and a leucine zipper-like motif
    • Blake, T. J. and W. Y. Langdon: The sequences of the human and mouse c-Cbl protooncogenes show v-Cbl was generated by a large truncation encompassing a proline-rich domain and a leucine zipper-like motif. Oncogene, 6:653-657 (1991).
    • (1991) Oncogene , vol.6 , pp. 653-657
    • Blake, T.J.1    Langdon, W.Y.2
  • 6
    • 0026525827 scopus 로고
    • A rearrangement of the c-cbl protooncogene in HUT78 T-lymphoma cells results in a truncated protein
    • Blake, T. J. and W. Y. Langdon: A rearrangement of the c-cbl protooncogene in HUT78 T-lymphoma cells results in a truncated protein. Oncogene, 7:757-762 (1992).
    • (1992) Oncogene , vol.7 , pp. 757-762
    • Blake, T.J.1    Langdon, W.Y.2
  • 7
    • 0027215275 scopus 로고
    • The truncation that generated the v-Cbl oncogene reveals an ability for nuclear transport, DNA binding and acute transformation
    • Blake, T., K. Heath, and W. Langdon: The truncation that generated the v-Cbl oncogene reveals an ability for nuclear transport, DNA binding and acute transformation. EMBO J., 12:2017-2026 (1993).
    • (1993) EMBO J. , vol.12 , pp. 2017-2026
    • Blake, T.1    Heath, K.2    Langdon, W.3
  • 8
    • 0030872395 scopus 로고    scopus 로고
    • Phosphotyrosine binding domain-dependent upregulation of the platelet-derived growth factor receptor a signaling cascade by transforming mutants of Cbl: Implications for Cbl's function and oncogenicity
    • Bonita, D. P., S. Miyake, M. L. Lupher, W. Y. Langdon, and H. Band: Phosphotyrosine binding domain-dependent upregulation of the platelet-derived growth factor receptor a signaling cascade by transforming mutants of Cbl: implications for Cbl's function and oncogenicity. Mol. Cell. Biol., 17:4597-4610 (1997).
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 4597-4610
    • Bonita, D.P.1    Miyake, S.2    Lupher, M.L.3    Langdon, W.Y.4    Band, H.5
  • 9
    • 0030812812 scopus 로고    scopus 로고
    • Maintenance of human T cell anergy: Blocking of IL-2 gene transcription by activated Rap-1
    • Boussiotis, V. A., G. J. Freeman, A. Berezovskaya, D. L. Barber, and L. M. Nadler: Maintenance of human T cell anergy: blocking of IL-2 gene transcription by activated Rap-1. Science, 278:124-128 (1997).
    • (1997) Science , vol.278 , pp. 124-128
    • Boussiotis, V.A.1    Freeman, G.J.2    Berezovskaya, A.3    Barber, D.L.4    Nadler, L.M.5
  • 10
    • 0028865896 scopus 로고
    • The protein product of the c-Cbl oncogene rapidly complexes with the EGF receptor and is tyrosine phosphorylated following EGF stimulation
    • Bowtell, D. D. L. and W. Y. Langdon: The protein product of the c-Cbl oncogene rapidly complexes with the EGF receptor and is tyrosine phosphorylated following EGF stimulation. Oncogene, 11:1561-1567 (1995).
    • (1995) Oncogene , vol.11 , pp. 1561-1567
    • Bowtell, D.D.L.1    Langdon, W.Y.2
  • 11
    • 0027153103 scopus 로고
    • Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor
    • Buday, L. and J. Downward: Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor. Cell, 73:611-620 (1993).
    • (1993) Cell , vol.73 , pp. 611-620
    • Buday, L.1    Downward, J.2
  • 12
    • 0028857006 scopus 로고
    • Downregulation of the Ras activation pathway by MAP kinase phosphorylation of Sos
    • Buday, L., P. H. Warne, and J. Downward: Downregulation of the Ras activation pathway by MAP kinase phosphorylation of Sos. Oncogene, 11:1327-1331 (1995).
    • (1995) Oncogene , vol.11 , pp. 1327-1331
    • Buday, L.1    Warne, P.H.2    Downward, J.3
  • 13
    • 0029664998 scopus 로고    scopus 로고
    • Interactions of Cbl with two adaptor proteins, Grb2 and Crk, upon T cell activation
    • Buday, L., A. Khwaja, S. Sipeki, A. Farago, and J. Downward: Interactions of Cbl with two adaptor proteins, Grb2 and Crk, upon T cell activation. J. Biol. Chem., 271:6159-6163 (1996).
    • (1996) J. Biol. Chem. , vol.271 , pp. 6159-6163
    • Buday, L.1    Khwaja, A.2    Sipeki, S.3    Farago, A.4    Downward, J.5
  • 14
    • 0030713407 scopus 로고    scopus 로고
    • Cbl-b, a member of the Sli-1/c-Cbl protein family, inhibits Vav-mediated c-Jun N-terminal kinase activation
    • Bustelo, X. R., P. Crespo, M. Lopez-Barahona, J. S. Gutkind, and M. Barbacid: Cbl-b, a member of the Sli-1/c-Cbl protein family, inhibits Vav-mediated c-Jun N-terminal kinase activation. Oncogene, 15:2511-2520 (1997).
    • (1997) Oncogene , vol.15 , pp. 2511-2520
    • Bustelo, X.R.1    Crespo, P.2    Lopez-Barahona, M.3    Gutkind, J.S.4    Barbacid, M.5
  • 16
    • 0026608178 scopus 로고
    • C. elegans cell signaling gene sem-5 encodes a protein with SH2 and SH3 domains
    • Clark, S. G., M. J. Stern, and H. R. Horvitz: C. elegans cell signaling gene sem-5 encodes a protein with SH2 and SH3 domains. Nature, 356:340-344 (1990).
    • (1990) Nature , vol.356 , pp. 340-344
    • Clark, S.G.1    Stern, M.J.2    Horvitz, H.R.3
  • 17
    • 0024411243 scopus 로고
    • Sequence requirements for synthetic peptide-mediated translocation to the nucleus
    • Chelsky, D., R. Ralph, and G. Jonak: Sequence requirements for synthetic peptide-mediated translocation to the nucleus. Mol. Cell. Biol., 9:2487-2492 (1989).
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 2487-2492
    • Chelsky, D.1    Ralph, R.2    Jonak, G.3
  • 18
    • 0028899751 scopus 로고
    • Disassembly of son-of-sevenless proteins from Grb2 during p21ras desensitization by insulin
    • Cherniak, A. D., J. K. Klarlund, B. R. Conway, and M. P. Czech: Disassembly of son-of-sevenless proteins from Grb2 during p21ras desensitization by insulin. J. Biol. Chem., 270:1485-1488 (1995).
    • (1995) J. Biol. Chem. , vol.270 , pp. 1485-1488
    • Cherniak, A.D.1    Klarlund, J.K.2    Conway, B.R.3    Czech, M.P.4
  • 19
    • 0027170176 scopus 로고
    • RapV12 antagonizes Ras-dependent activation of ERK1 and ERK2 by LPA and EGF in Rat-1 fibroblasts
    • Cook, S. J., B. Rubinfield, I. Albert, and F. McCormick: RapV12 antagonizes Ras-dependent activation of ERK1 and ERK2 by LPA and EGF in Rat-1 fibroblasts. EMBO J., 12:3475-3485 (1993).
    • (1993) EMBO J. , vol.12 , pp. 3475-3485
    • Cook, S.J.1    Rubinfield, B.2    Albert, I.3    McCormick, F.4
  • 20
    • 0029098389 scopus 로고
    • The protein product of the c-Cbl protooncogene is phosphorylated after B cell receptor stimulation and binds the SH3 domain of Bruton's tyrosine kinase
    • Cory, G. O., R. C. Lovering, S.; Hinshelwood, L. MacCarthy-Morrogh, R. J. Levinsky, and C. Kinnon: The protein product of the c-Cbl protooncogene is phosphorylated after B cell receptor stimulation and binds the SH3 domain of Bruton's tyrosine kinase. J. Exp. Med., 182:611-615(1995).
    • (1995) J. Exp. Med. , vol.182 , pp. 611-615
    • Cory, G.O.1    Lovering, R.C.2    Hinshelwood, S.3    MacCarthy-Morrogh, L.4    Levinsky, R.J.5    Kinnon, C.6
  • 22
    • 0031033292 scopus 로고    scopus 로고
    • Phosphotyrosine dependent activation of Rac-1 GDP/GTP exchange by the vav protooncogene product
    • Crespo, P., K. E. Schuebel, A. A. Omstron, J. S. Gutkind, and X. R. Bustelo: Phosphotyrosine dependent activation of Rac-1 GDP/GTP exchange by the vav protooncogene product. Nature, 385:569-572 (1997).
    • (1997) Nature , vol.385 , pp. 569-572
    • Crespo, P.1    Schuebel, K.E.2    Omstron, A.A.3    Gutkind, J.S.4    Bustelo, X.R.5
  • 23
    • 0028926070 scopus 로고
    • Transmembrane signaling by antigen receptors of B and T lymphocytes
    • DeFranco, A. L.: Transmembrane signaling by antigen receptors of B and T lymphocytes. Curr. Opin. Cell. Biol., 7:163-175 (1995).
    • (1995) Curr. Opin. Cell. Biol. , vol.7 , pp. 163-175
    • DeFranco, A.L.1
  • 24
    • 0028027169 scopus 로고
    • The protein product of the c-Cbl protooncogene is the 120-kDa tyrosine-phosphorylated protein in Jurkat T cells activated via the T cell antigen receptor
    • Donovan, J. A., R. L. Wange, W. Y. Langdon, and L. E. Samelson: The protein product of the c-Cbl protooncogene is the 120-kDa tyrosine-phosphorylated protein in Jurkat T cells activated via the T cell antigen receptor. J. Biol. Chem., 269:22921-22924 (1994).
    • (1994) J. Biol. Chem. , vol.269 , pp. 22921-22924
    • Donovan, J.A.1    Wange, R.L.2    Langdon, W.Y.3    Samelson, L.E.4
  • 25
    • 0029662222 scopus 로고    scopus 로고
    • Regulation of the association of p120cbl with Grb2 in Jurkat cells
    • Donovan, J. A., Y. Ota, W. Y. Langdon, and L. E. Samelson: Regulation of the association of p120cbl with Grb2 in Jurkat cells. J. Biol. Chem., 271:26369-26374 (1996).
    • (1996) J. Biol. Chem. , vol.271 , pp. 26369-26374
    • Donovan, J.A.1    Ota, Y.2    Langdon, W.Y.3    Samelson, L.E.4
  • 27
    • 0021324827 scopus 로고
    • Histologic and cell surface antigen studies of hemotopoietic tumors induced by Cas-Br-M murine leukemia virus
    • Frederickson, T. N., W. Y. Langdon, P. M. Hoffman, J. W. Hartley, and H. C. Morse III: Histologic and cell surface antigen studies of hemotopoietic tumors induced by Cas-Br-M murine leukemia virus. J. Natl. Cancer Inst., 72:447-452 (1984).
    • (1984) J. Natl. Cancer Inst. , vol.72 , pp. 447-452
    • Frederickson, T.N.1    Langdon, W.Y.2    Hoffman, P.M.3    Hartley, J.W.4    Morse H.C. III5
  • 28
    • 0029051695 scopus 로고
    • The SH3 domain-binding T cell tyrosyl phosphoprotein p 120. Demonstration of its identity with the c-Cbl protooncogene product and in vivo complexes with Fyn, Grb2, and phosphatidylinositol 3-kinase
    • Fukazawa, T., K. A. Reedquist, T. Trub, S. Soltoff, G. Panchamoorthy, B. Druker, L. Cantley, S. E. Shoelson and H. Band: The SH3 domain-binding T cell tyrosyl phosphoprotein p 120. Demonstration of its identity with the c-Cbl protooncogene product and in vivo complexes with Fyn, Grb2, and phosphatidylinositol 3-kinase. J. Biol. Chem., 270:19141-19150 (1995).
    • (1995) J. Biol. Chem. , vol.270 , pp. 19141-19150
    • Fukazawa, T.1    Reedquist, K.A.2    Trub, T.3    Soltoff, S.4    Panchamoorthy, G.5    Druker, B.6    Cantley, L.7    Shoelson, S.E.8    Band, H.9
  • 29
    • 17544365654 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of Cbl upon epidermal growth factor (EGF) Stimulation and its association with Eof receptor and downstream signaling proteins
    • Fukazawa, T., S. Miyake, V. Band, and H. Band: Tyrosine phosphorylation of Cbl upon epidermal growth factor (EGF) Stimulation and its association with EOF receptor and downstream signaling proteins. J. Biol. Chem., 271:14554-14559 (1996).
    • (1996) J. Biol. Chem. , vol.271 , pp. 14554-14559
    • Fukazawa, T.1    Miyake, S.2    Band, V.3    Band, H.4
  • 30
    • 0029094649 scopus 로고
    • Tyrosine phosphorylation of the c-Cbl protooncogene protein product and association with epidermal growth factor (EGF) receptor upon EGF stimulation
    • Galisteo, M. L., I. Dikic, A. G. Batzer, W. Y. Langdon, and J. Schlessinger: Tyrosine phosphorylation of the c-Cbl protooncogene protein product and association with epidermal growth factor (EGF) receptor upon EGF stimulation. J. Biol. Chem., 270:20242-20245 (1995).
    • (1995) J. Biol. Chem. , vol.270 , pp. 20242-20245
    • Galisteo, M.L.1    Dikic, I.2    Batzer, A.G.3    Langdon, W.Y.4    Schlessinger, J.5
  • 33
    • 0025633434 scopus 로고
    • Let-60, a gene that specifies cell fates during C. elegans vulval induction, encodes a ras protein
    • Han, M. and P. W. Sternberg: let-60, a gene that specifies cell fates during C. elegans vulval induction, encodes a ras protein. Cell, 63:921-931 (1990).
    • (1990) Cell , vol.63 , pp. 921-931
    • Han, M.1    Sternberg, P.W.2
  • 34
    • 0025932448 scopus 로고
    • The Drosophila roughened mutation: Activation of a rap homolog disrupts eye development and interferes with cell determination
    • Hariharen, I. K., R. W. Carthew, and G. M. Rubin: The Drosophila roughened mutation: activation of a rap homolog disrupts eye development and interferes with cell determination. Cell, 67:717-722 (1991).
    • (1991) Cell , vol.67 , pp. 717-722
    • Hariharen, I.K.1    Carthew, R.W.2    Rubin, G.M.3
  • 35
    • 0017157131 scopus 로고
    • Naturally occurring murine leukemia viruses in wild mice: Characterization of a new "amphotropic" class
    • Hartley J. W. and W. P. Row: Naturally occurring murine leukemia viruses in wild mice: characterization of a new "amphotropic" class. J. Virol., 19:19-25 (1976).
    • (1976) J. Virol. , vol.19 , pp. 19-25
    • Hartley, J.W.1    Row, W.P.2
  • 36
    • 0017337438 scopus 로고
    • A new class of murine leukemia virus associated with development of spontaneous lymphomas
    • Hartley, J. W., N. K. Wolford, L. J. Old, and W. P. Rowe: A new class of murine leukemia virus associated with development of spontaneous lymphomas. Proc. Natl. Acad. Sci. U.S.A., 74:789-792 (1977).
    • (1977) Proc. Natl. Acad. Sci. U.S.A. , vol.74 , pp. 789-792
    • Hartley, J.W.1    Wolford, N.K.2    Old, L.J.3    Rowe, W.P.4
  • 37
    • 0029117423 scopus 로고
    • Specific association of the β isoform of the p85 subunit of phosphatidylinositol-3 kinase with the protooncogene c-Cbl
    • Hartley, D., H. Meisner, and S. Corvera: Specific association of the β isoform of the p85 subunit of phosphatidylinositol-3 kinase with the protooncogene c-Cbl. J. Biol. Chem., 270:18260-18263 (1995).
    • (1995) J. Biol. Chem. , vol.270 , pp. 18260-18263
    • Hartley, D.1    Meisner, H.2    Corvera, S.3
  • 38
    • 0025355524 scopus 로고
    • Inhibition of the ras p21 GTPase-activating protein-stimulated GTPase activity of c-Ha-ras p21 by smg p21 having the same putative effector domain as ras p21s
    • Hata, Y., A. Kikuchi, T. Sasaki, M. D. Schaber, J. B. Gibbs, and Y. Takai: Inhibition of the ras p21 GTPase-activating protein-stimulated GTPase activity of c-Ha-ras p21 by smg p21 having the same putative effector domain as ras p21s. J. Biol. Chem., 265:7104-7107(1990).
    • (1990) J. Biol. Chem. , vol.265 , pp. 7104-7107
    • Hata, Y.1    Kikuchi, A.2    Sasaki, T.3    Schaber, M.D.4    Gibbs, J.B.5    Takai, Y.6
  • 39
    • 0025200830 scopus 로고
    • Characterization of VPS34, a gene required for vacuolar protein sorting and vacuole segragation in Saccharomyces cerevisiae
    • Herman, P. K. and S. D. Emr: Characterization of VPS34, a gene required for vacuolar protein sorting and vacuole segragation in Saccharomyces cerevisiae. Mol. Cell. Biol., 10:6742-6754 (1990).
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 6742-6754
    • Herman, P.K.1    Emr, S.D.2
  • 40
    • 0030790509 scopus 로고    scopus 로고
    • D-Cbl, the Drosophila homologue of the c-Cbl protooncogene, interacts with the Drosophila EGF receptor in vivo, despite lacking C-terminal adaptor binding sites
    • Hime, G. R., M. P. Dhungat, A. Ng, and D. D. L. Bowtell: D-Cbl, the Drosophila homologue of the c-Cbl protooncogene, interacts with the Drosophila EGF receptor in vivo, despite lacking C-terminal adaptor binding sites. Oncogene, 14:2709-2719 (1997).
    • (1997) Oncogene , vol.14 , pp. 2709-2719
    • Hime, G.R.1    Dhungat, M.P.2    Ng, A.3    Bowtell, D.D.L.4
  • 41
    • 0027179910 scopus 로고
    • Isolation and chromosomal localization of CRKL, a human crk-like gene
    • ten Hoeve, J., C. Morris, N. Heisterkamp, and J. Groffen: Isolation and chromosomal localization of CRKL, a human crk-like gene. Oncogene, 8:2469-2474 (1993).
    • (1993) Oncogene , vol.8 , pp. 2469-2474
    • Ten Hoeve, J.1    Morris, C.2    Heisterkamp, N.3    Groffen, J.4
  • 43
    • 0028351218 scopus 로고
    • Disruption of PDGF receptor trafficking by mutation of its PI-3 kinase binding sites
    • Joly, M., A. Kazlauskas, F. S. Fay, and S. Corvera: Disruption of PDGF receptor trafficking by mutation of its PI-3 kinase binding sites. Science, 263:684-687 (1994).
    • (1994) Science , vol.263 , pp. 684-687
    • Joly, M.1    Kazlauskas, A.2    Fay, F.S.3    Corvera, S.4
  • 44
    • 0029164951 scopus 로고
    • CrkI is complexed with tyrosine phosphorylated Cbl in Ph-positive leukemia
    • de Jong, R., J. ten Hoeve, N. Heisterkamp, and J. Kuffen: CrkI is complexed with tyrosine phosphorylated Cbl in Ph-positive leukemia: J. Biol. Chem., 270:21468-21471 (1995).
    • (1995) J. Biol. Chem. , vol.270 , pp. 21468-21471
    • De Jong, R.1    Ten Hoeve, J.2    Heisterkamp, N.3    Kuffen, J.4
  • 45
    • 0028920694 scopus 로고
    • Sli-1, a negative regulator of let-23 mediated signaling in C. elegans
    • Jongeward, G. D., T. R. Clandinin, and P. W. Sternberg: Sli-1, a negative regulator of let-23 mediated signaling in C. elegans. Genetics, 139:1553-1566 (1995).
    • (1995) Genetics , vol.139 , pp. 1553-1566
    • Jongeward, G.D.1    Clandinin, T.R.2    Sternberg, P.W.3
  • 47
    • 0029006745 scopus 로고
    • Cloning and characterication of cbl-b: A SH3 binding protein with homology to the c-Cbl protooncogene
    • Keane, M. M., O. M. Rivero-Lezcano, J. A. Mitchell, K. C. Robbins, and S. Lipkowitz: Cloning and characterication of cbl-b: a SH3 binding protein with homology to the c-Cbl protooncogene. Oncogene, 10:2367-2377 (1995).
    • (1995) Oncogene , vol.10 , pp. 2367-2377
    • Keane, M.M.1    Rivero-Lezcano, O.M.2    Mitchell, J.A.3    Robbins, K.C.4    Lipkowitz, S.5
  • 48
    • 0029666431 scopus 로고    scopus 로고
    • Networks of interaction of p120cbl and p130cas with Crk and Grb2 adaptor proteins
    • Khwaja, A., B. Hallberg, P. H. Warne, and J. Downward: Networks of interaction of p120cbl and p130cas with Crk and Grb2 adaptor proteins. Oncogene, 12:2491-2498 (1996).
    • (1996) Oncogene , vol.12 , pp. 2491-2498
    • Khwaja, A.1    Hallberg, B.2    Warne, P.H.3    Downward, J.4
  • 49
    • 0028879084 scopus 로고
    • Association of activated phosphatidylinositol 3-kinase with p120Cbl in antigen receptor-ligated B cells
    • Kim, T. J., Y.-T. Kim, and S. Pillai: Association of activated phosphatidylinositol 3-kinase with p120Cbl in antigen receptor-ligated B cells. J. Biol. Chem., 270:27504-27509 (1995).
    • (1995) J. Biol. Chem. , vol.270 , pp. 27504-27509
    • Kim, T.J.1    Kim, Y.-T.2    Pillai, S.3
  • 50
    • 0024600222 scopus 로고
    • A ras-related gene with transformation suppressor activity
    • Kitayama, H., Y. Sugimoto, T. Matsuzaki, Y. Ikawa, and M. Noda: A ras-related gene with transformation suppressor activity. Cell, 56:77-84 (1989).
    • (1989) Cell , vol.56 , pp. 77-84
    • Kitayama, H.1    Sugimoto, Y.2    Matsuzaki, T.3    Ikawa, Y.4    Noda, M.5
  • 51
    • 0025368594 scopus 로고
    • Genetic analysis of the Kirsten-ras-revertant 1 gene: Potentiation of its tumor suppressor activity by specific point mutations
    • Kitayama, H., T. Matsuzaki, Y. Ikawa, and M. Noda: Genetic analysis of the Kirsten-ras-revertant 1 gene: potentiation of its tumor suppressor activity by specific point mutations. Proc. Natl. Acad. Sci. U.S.A., 87:4284-4288 (1990).
    • (1990) Proc. Natl. Acad. Sci. U.S.A. , vol.87 , pp. 4284-4288
    • Kitayama, H.1    Matsuzaki, T.2    Ikawa, Y.3    Noda, M.4
  • 52
    • 0030070331 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of the c-Cbl protooncogene product mediated by cell surface antigen CD38 in HL-60 cells
    • Kontani, K., I. Kukimoto, H. Nishina, S. Hoshino, O. Hazeki, Y. Kanaho, and T. Katada: Tyrosine phosphorylation of the c-Cbl protooncogene product mediated by cell surface antigen CD38 in HL-60 cells. J. Biol. Chem., 271:1534-1537 (1996).
    • (1996) J. Biol. Chem. , vol.271 , pp. 1534-1537
    • Kontani, K.1    Kukimoto, I.2    Nishina, H.3    Hoshino, S.4    Hazeki, O.5    Kanaho, Y.6    Katada, T.7
  • 53
    • 0024295767 scopus 로고
    • The leucine zipper: A hypothetical structure common to a new class of DNA binding proteins
    • Landschutz, W. H., P. F. Johnson, and S. L. McKnight: The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins. Science, 240:1759-1764 (1988).
    • (1988) Science , vol.240 , pp. 1759-1764
    • Landschutz, W.H.1    Johnson, P.F.2    McKnight, S.L.3
  • 55
    • 0024467516 scopus 로고
    • The c-cbl protooncogene is preferentially expressed in thymus and testis tissue and encodes a nuclear protein
    • Langdon, W. Y., C. H. Hyland, R. J. Grumont, and H. C. Morse, III: The c-cbl protooncogene is preferentially expressed in thymus and testis tissue and encodes a nuclear protein. J. Virol, 63:5420-5424 (1989a).
    • (1989) J. Virol , vol.63 , pp. 5420-5424
    • Langdon, W.Y.1    Hyland, C.H.2    Grumont, R.J.3    Morse H.C. III4
  • 56
    • 0024593048 scopus 로고
    • V-Cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas
    • Langdon, W. Y., J. W. Hartley, S. P. Klinken, S. K. Ruscetti, and H. C. Morse, III: v-Cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas. Proc. Natl. Acad. Sci. USA, 86:1168-1172 (1989b).
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 1168-1172
    • Langdon, W.Y.1    Hartley, J.W.2    Klinken, S.P.3    Ruscetti, S.K.4    Morse H.C. III5
  • 57
    • 0028179670 scopus 로고
    • Unc-101, a gene required for many aspects of Caenorhabditis elegans development and behavior, encodes a clathrin-associated protein
    • Lee, J., G. D. Jongeward, and P. W. Sternberg: unc-101, a gene required for many aspects of Caenorhabditis elegans development and behavior, encodes a clathrin-associated protein. Genes Dev., 8:60-73 (1994).
    • (1994) Genes Dev. , vol.8 , pp. 60-73
    • Lee, J.1    Jongeward, G.D.2    Sternberg, P.W.3
  • 58
    • 0029917264 scopus 로고    scopus 로고
    • Coupling of the c-Cbl protooncogene product to ErbB-1 /EGF-receptor but not to other ErbB proteins
    • Levkowitz, G., L. N. Klapper, E. Tzahar, A. Freywald, M. Sela, and Y. Yarden: Coupling of the c-Cbl protooncogene product to ErbB-1 /EGF-receptor but not to other ErbB proteins. Oncogene, 12:1117-1125 (1996).
    • (1996) Oncogene , vol.12 , pp. 1117-1125
    • Levkowitz, G.1    Klapper, L.N.2    Tzahar, E.3    Freywald, A.4    Sela, M.5    Yarden, Y.6
  • 59
    • 15844419127 scopus 로고    scopus 로고
    • Activation-modulated association of 14-3-3 proteins with Cbl in T cells
    • Liu, Y.-C., C. Elly, H. Yoshida, N. Bonnefoy-Berard, and A. Altman: Activation-modulated association of 14-3-3 proteins with Cbl in T cells. J. Biol. Chem., 271:14591-14595 (1996).
    • (1996) J. Biol. Chem. , vol.271 , pp. 14591-14595
    • Liu, Y.-C.1    Elly, C.2    Yoshida, H.3    Bonnefoy-Berard, N.4    Altman, A.5
  • 60
    • 0030614453 scopus 로고    scopus 로고
    • 2+-stimulated activation of nuclear factor of activated T cells by a constitutively active Cbl mutant in T cells
    • 2+-stimulated activation of nuclear factor of activated T cells by a constitutively active Cbl mutant in T cells. J. Biol. Chem., 272:168-173 (1997).
    • (1997) J. Biol. Chem. , vol.272 , pp. 168-173
    • Liu, Y.-C.1    Elly, C.2    Langdon, W.Y.3    Altman, A.4
  • 62
    • 10144243337 scopus 로고    scopus 로고
    • A novel phosphotyrosinebinding domain in the N-terminal transforming region of Cbl interacts directly and selectively with Zap-70 in T cells
    • Lupher, M. L., Jr., K. A. Reedquist, S. Miyake, W. Y. Langdon, and H. Band: A novel phosphotyrosinebinding domain in the N-terminal transforming region of Cbl interacts directly and selectively with Zap-70 in T cells. J. Biol. Chem. 271:24063-24068 (1996).
    • (1996) J. Biol. Chem. , vol.271 , pp. 24063-24068
    • Lupher M.L., Jr.1    Reedquist, K.A.2    Miyake, S.3    Langdon, W.Y.4    Band, H.5
  • 63
    • 14444276991 scopus 로고    scopus 로고
    • The Cbl phosphotyrosine binding domain selects a D(N/D)XpY motif and binds to the Tyr292 negative regulatoy tyrosine phosphorylation site of ZAP-70
    • Lupher, M. L., Z. Songyang, S. E. Shoelson, L. C. Cantley, and H. Band: The Cbl phosphotyrosine binding domain selects a D(N/D)XpY motif and binds to the Tyr292 negative regulatoy tyrosine phosphorylation site of ZAP-70. J. Biol. Chem. 272:33140-33144 (1997).
    • (1997) J. Biol. Chem. , vol.272 , pp. 33140-33144
    • Lupher, M.L.1    Songyang, Z.2    Shoelson, S.E.3    Cantley, L.C.4    Band, H.5
  • 64
    • 0028901016 scopus 로고
    • Identification of the major tyrosine kinase substrate in signaling complexes formed after engagement of Feγ receptors
    • Marcilla, A., O. M. Rivero-Lezcano, A. Agarwal, and K. C. Robbins: Identification of the major tyrosine kinase substrate in signaling complexes formed after engagement of Feγ receptors. J. Biol. Chem. 270:9115-9120 (1995).
    • (1995) J. Biol. Chem. , vol.270 , pp. 9115-9120
    • Marcilla, A.1    Rivero-Lezcano, O.M.2    Agarwal, A.3    Robbins, K.C.4
  • 66
    • 0028122971 scopus 로고
    • CRK protein binds to two guanine nucleotide-releasing proteins for the Ras family and modulates nerve growth factor-induced activation of Ras in PC12 cells
    • Matsuda, M., Y. Hashimoto, K. Muroya, H. Hasegawa, T. Kurata, S. Tanaka, S. Nakamura, and S. Hattori: CRK protein binds to two guanine nucleotide-releasing proteins for the Ras family and modulates nerve growth factor-induced activation of Ras in PC12 cells. Mol. Cell. Biol., 14:5495-5500 (1994).
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 5495-5500
    • Matsuda, M.1    Hashimoto, Y.2    Muroya, K.3    Hasegawa, H.4    Kurata, T.5    Tanaka, S.6    Nakamura, S.7    Hattori, S.8
  • 67
    • 0028885860 scopus 로고
    • Coupling of the protooncogene product c-Cbl to the epidermal growth factor receptor
    • Meisner, H. and M. P. Czech: Coupling of the protooncogene product c-Cbl to the epidermal growth factor receptor. J. Biol. Chem., 270:25332-25335 (1995).
    • (1995) J. Biol. Chem. , vol.270 , pp. 25332-25335
    • Meisner, H.1    Czech, M.P.2
  • 68
    • 0029034440 scopus 로고
    • Interaction of Cbl with Grb2 and phosphatidylinositol 3′-kinase in activated Jurkat T cells
    • Meisner, H., B. R. Conway, D. Hartley, and M. P. Czech: Interaction of Cbl with Grb2 and phosphatidylinositol 3′-kinase in activated Jurkat T cells. Mol. Cell. Biol., 15:3571-3578 (1995).
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 3571-3578
    • Meisner, H.1    Conway, B.R.2    Hartley, D.3    Czech, M.P.4
  • 69
    • 0030978136 scopus 로고    scopus 로고
    • Interactions of Drosophila Cbl with epidermal growth factor receptors and role of Cbl in R7 photoreceptor cell development
    • Meisner, H., A. Daga, J. Buxton, B. Fernandez, A. Chawla, U. Banerjee, and M. Czech: Interactions of Drosophila Cbl with epidermal growth factor receptors and role of Cbl in R7 photoreceptor cell development. Mol. Cell. Biol., 17:2217-2225 (1997).
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 2217-2225
    • Meisner, H.1    Daga, A.2    Buxton, J.3    Fernandez, B.4    Chawla, A.5    Banerjee, U.6    Czech, M.7
  • 70
    • 0027990252 scopus 로고
    • Expression of the c-cbl protooncogene is modulated during differentiation but not during induction of proliferation
    • Mushinski, J. F., J. Goodnight, E. Rudikoff, H. C. Morse, III, and W. Y. Langdon: Expression of the c-cbl protooncogene is modulated during differentiation but not during induction of proliferation. Oncogene, 9:2489-2497 (1994).
    • (1994) Oncogene , vol.9 , pp. 2489-2497
    • Mushinski, J.F.1    Goodnight, J.2    Rudikoff, E.3    Morse H.C. III4    Langdon, W.Y.5
  • 71
    • 0028932614 scopus 로고
    • The protooncogene product c-cbl becomes tyrosine phosphorylated by stimulation with GM-CSF or Epo and constitutively binds to the SH3 domain of Grb2/Ash in human hematopoietic cells
    • Odai, H., K. Sasaki, A. Iwamatsu, Y. Hanazono, T. Tanaka, K. Mitanai, Y. Yazaki, and H. Hirai: The protooncogene product c-cbl becomes tyrosine phosphorylated by stimulation with GM-CSF or Epo and constitutively binds to the SH3 domain of Grb2/Ash in human hematopoietic cells. J. Biol. Chem., 270:10800-10805 (1995).
    • (1995) J. Biol. Chem. , vol.270 , pp. 10800-10805
    • Odai, H.1    Sasaki, K.2    Iwamatsu, A.3    Hanazono, Y.4    Tanaka, T.5    Mitanai, K.6    Yazaki, Y.7    Hirai, H.8
  • 72
    • 0031034681 scopus 로고    scopus 로고
    • The protooncogene product p 120cbl links c-Src and phosphatidylinositol 3′-kinase to the integrin signaling pathway
    • Ojaniemi, M., S. S. Martini, F. Dolfi, J. M. Olefsky, and K. Vuori: The protooncogene product p 120cbl links c-Src and phosphatidylinositol 3′-kinase to the integrin signaling pathway. J. Biol. Chem., 272:3780-3787 (1997).
    • (1997) J. Biol. Chem. , vol.272 , pp. 3780-3787
    • Ojaniemi, M.1    Martini, S.S.2    Dolfi, F.3    Olefsky, J.M.4    Vuori, K.5
  • 73
    • 0029852837 scopus 로고    scopus 로고
    • Characterization of Cbl tyrosine phosphorylation and a Cbl-Syk complex in RBL-2H3 cells
    • Ota, Y., L. O. Beitz, A. M. Scharenberg, J. A. Donovan, J.-P. Kinet, and L. E. Samelson: Characterization of Cbl tyrosine phosphorylation and a Cbl-Syk complex in RBL-2H3 cells. J. Exp. Med., 184:1713-1723 (1996).
    • (1996) J. Exp. Med. , vol.184 , pp. 1713-1723
    • Ota, Y.1    Beitz, L.O.2    Scharenberg, A.M.3    Donovan, J.A.4    Kinet, J.-P.5    Samelson, L.E.6
  • 74
    • 0030889218 scopus 로고    scopus 로고
    • The product of the protooncogene c-Cbl: A negative regulator of the Syk tyrosine kinase
    • Ota, Y. and L.E. Samelson: The product of the protooncogene c-Cbl: a negative regulator of the Syk tyrosine kinase. Science, 276:418-420 (1997).
    • (1997) Science , vol.276 , pp. 418-420
    • Ota, Y.1    Samelson, L.E.2
  • 75
    • 0029671073 scopus 로고    scopus 로고
    • P120cbl is a major substrate of tyrosine phosphorylation upon B cell antigen receptor stimulation and interacts in vivo with Fyn and Syk tyrosine kinases, Grb2 and Shc adaptors, and the p85 subunit of phosphatidylinositol 3-kinase
    • Panchamoorthy, G., T. Fukazawa, S. Miyake, S. Soltoff, K. Reedquist, B. Druker, S. Shoelson, L. Cantley, and H. Band: p120cbl is a major substrate of tyrosine phosphorylation upon B cell antigen receptor stimulation and interacts in vivo with Fyn and Syk tyrosine kinases, Grb2 and Shc adaptors, and the p85 subunit of phosphatidylinositol 3-kinase. J. Biol. Chem., 271:3187-3194 (1996).
    • (1996) J. Biol. Chem. , vol.271 , pp. 3187-3194
    • Panchamoorthy, G.1    Fukazawa, T.2    Miyake, S.3    Soltoff, S.4    Reedquist, K.5    Druker, B.6    Shoelson, S.7    Cantley, L.8    Band, H.9
  • 76
    • 0028257943 scopus 로고
    • Rapid T-cell receptor mediated tyrosine phosphorylation of p 120, an Fyn/ Lck Src homology 3 domain-binding protein
    • Reedquist, K. A., T. Fukazawa, B. Druker, G. Panchamoorthy, S. E. Shoelson, and H. Band: Rapid T-cell receptor mediated tyrosine phosphorylation of p 120, an Fyn/ Lck Src homology 3 domain-binding protein. Proc. Natl. Acad. Sci. U.S.A., 91:4135-4139 (1994).
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 4135-4139
    • Reedquist, K.A.1    Fukazawa, T.2    Druker, B.3    Panchamoorthy, G.4    Shoelson, S.E.5    Band, H.6
  • 77
    • 0029876948 scopus 로고    scopus 로고
    • Stimulation through the T cell receptor induces Cbl association with Crk proteins and the guanine nucleotide exchange protein C3G
    • Reedquist, K. A., T. Fukazawa, G. Panchamoorthy, W. Y. Langdon, S. E, Shoelson, B. J. Druker, and H. Band: Stimulation through the T cell receptor induces Cbl association with Crk proteins and the guanine nucleotide exchange protein C3G. J. Biol. Chem., 271:8435-8442 (1996).
    • (1996) J. Biol. Chem. , vol.271 , pp. 8435-8442
    • Reedquist, K.A.1    Fukazawa, T.2    Panchamoorthy, G.3    Langdon, W.Y.4    Shoelson, S.E.5    Druker, B.J.6    Band, H.7
  • 79
    • 0030712944 scopus 로고    scopus 로고
    • Cbl-mediated regulation of T cell receptor-induced AP1 activation. Implications for activation via the Ras signaling pathway
    • Rellahan, B. L., L. J. Graham, B. Stoica, K. E. DeBeil, and E. Bonvini: Cbl-mediated regulation of T cell receptor-induced AP1 activation. Implications for activation via the Ras signaling pathway. J. Biol. Chem., 272:30806-30811 (1997).
    • (1997) J. Biol. Chem. , vol.272 , pp. 30806-30811
    • Rellahan, B.L.1    Graham, L.J.2    Stoica, B.3    DeBeil, K.E.4    Bonvini, E.5
  • 80
    • 0029655999 scopus 로고    scopus 로고
    • The product of the cbl oncogene forms stable complexes in vivo with endogenous Crk in a tyrosine phosphorylation-dependent manner
    • Ribon, V., S. Hubbell, R. Herrera, and A. R. Saltiel: The product of the cbl oncogene forms stable complexes in vivo with endogenous Crk in a tyrosine phosphorylation-dependent manner. Mol. Cell. Biol., 16:45-52 (1996).
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 45-52
    • Ribon, V.1    Hubbell, S.2    Herrera, R.3    Saltiel, A.R.4
  • 81
    • 0028308576 scopus 로고
    • Physical association between Src homology 3 elements and the protein product of the c-cbl protooncogene
    • Rivero-Lezcano, O. M., J. H. Sameshima, A. Marcilla, and K. C. Robbins: Physical association between Src homology 3 elements and the protein product of the c-cbl protooncogene. J. Biol. Chem., 269:17363-17366 (1994).
    • (1994) J. Biol. Chem. , vol.269 , pp. 17363-17366
    • Rivero-Lezcano, O.M.1    Sameshima, J.H.2    Marcilla, A.3    Robbins, K.C.4
  • 82
    • 0031558787 scopus 로고    scopus 로고
    • A c-Cbl yeast two-hybrid screen reveals interactions with 14-3-3 isoforms and cytoskeletal components
    • Robertson, H., W. Y. Langdon, C. B. F. Thien, and D. D. L. Bowtell: A c-Cbl yeast two-hybrid screen reveals interactions with 14-3-3 isoforms and cytoskeletal components. Biochem. Biophys. Res. Commun., 240:46-50 (1997).
    • (1997) Biochem. Biophys. Res. Commun. , vol.240 , pp. 46-50
    • Robertson, H.1    Langdon, W.Y.2    Thien, C.B.F.3    Bowtell, D.D.L.4
  • 83
    • 0028795721 scopus 로고
    • DNA synthesis induced by some but not all growth factors requires Src family tyrosine kinases
    • Roche, S., M. Koegl, M. V. Barone, M. F. Roussel and S. A. Courtneidge: DNA synthesis induced by some but not all growth factors requires Src family tyrosine kinases. Mol. Cell. Biol., 15:1102-1109 (1995).
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 1102-1109
    • Roche, S.1    Koegl, M.2    Barone, M.V.3    Roussel, M.F.4    Courtneidge, S.A.5
  • 85
    • 0029669975 scopus 로고    scopus 로고
    • The protooncogene product p120cbl and the adaptor proteins CrkL and c-Crk link C-Abl, p 190bcr-abl and p210bcr/abl to the phosphatidylinositol-3′ kinase pathway
    • Sattler, M., R. Salgia, K. Okuda, N. Uemura, M. A. Durstin, E. Pisick, G. Xu, J-L. Li, K. V. Prasad, and J. D. Griffin: The protooncogene product p120cbl and the adaptor proteins CrkL and c-Crk link C-Abl, p 190bcr-abl and p210bcr/abl to the phosphatidylinositol-3′ kinase pathway. Oncogene, 12:839-846 (1996).
    • (1996) Oncogene , vol.12 , pp. 839-846
    • Sattler, M.1    Salgia, R.2    Okuda, K.3    Uemura, N.4    Durstin, M.A.5    Pisick, E.6    Xu, G.7    Li, J.-L.8    Prasad, K.V.9    Griffin, J.D.10
  • 88
    • 0029832241 scopus 로고    scopus 로고
    • Isolation and characterization of murine vav2, a member of the vav family of protooncogenes
    • Schuebel, K. E., X. R. Bustelo, D. A. Nielsen, B. J. Song, M. Barbacid, D. Goldman, and I. J. Lee: Isolation and characterization of murine vav2, a member of the vav family of protooncogenes. Oncogene, 13:363-371 (1996).
    • (1996) Oncogene , vol.13 , pp. 363-371
    • Schuebel, K.E.1    Bustelo, X.R.2    Nielsen, D.A.3    Song, B.J.4    Barbacid, M.5    Goldman, D.6    Lee, I.J.7
  • 89
    • 0028147237 scopus 로고
    • B cell antigen receptor stimulation induces formation of a Shc-Grb2 complex containing multiple tyrosine-phosphorylated proteins
    • Smit, L., A. M. M. de Vries-Smits, J. L. Bos, and J. Borst: B cell antigen receptor stimulation induces formation of a Shc-Grb2 complex containing multiple tyrosine-phosphorylated proteins. J. Biol. Chem., 269:20209-20212 (1994).
    • (1994) J. Biol. Chem. , vol.269 , pp. 20209-20212
    • Smit, L.1    De Vries-Smits, A.M.M.2    Bos, J.L.3    Borst, J.4
  • 90
    • 0029928127 scopus 로고    scopus 로고
    • Sos, Vav, and C3G participate in B cell receptor-induced signaling pathways and differentially associate with Shc-Grb2, Crk, and Crk-L adaptors
    • Smit, L., G. van der Horst, and J. Borst: Sos, Vav, and C3G participate in B cell receptor-induced signaling pathways and differentially associate with Shc-Grb2, Crk, and Crk-L adaptors. J. Biol. Chem., 271:8564-8569 (1996a).
    • (1996) J. Biol. Chem. , vol.271 , pp. 8564-8569
    • Smit, L.1    Van der Horst, G.2    Borst, J.3
  • 91
    • 0029831323 scopus 로고    scopus 로고
    • Formation of Shc/ Grb2 and Crk adaptor complexes containing tyrosine phosphorylated Cbl upon stimulation of the B-cell antigen receptor
    • Smit, L., G. van der Horst, and J. Borst: Formation of Shc/ Grb2 and Crk adaptor complexes containing tyrosine phosphorylated Cbl upon stimulation of the B-cell antigen receptor. Oncogene, 12:381-389 (1996b).
    • (1996) Oncogene , vol.12 , pp. 381-389
    • Smit, L.1    Van der Horst, G.2    Borst, J.3
  • 92
    • 0029671427 scopus 로고    scopus 로고
    • P120cbl is a cytosolic adapter protein that associates with phosphoinositide 3-kinase in response to epidermal growth factor in PC 12 and other cells
    • Soltoff, S. P. and L. C. Cantley: P120cbl is a cytosolic adapter protein that associates with phosphoinositide 3-kinase in response to epidermal growth factor in PC 12 and other cells. J. Biol. Chem. 271:563-577 (1996).
    • (1996) J. Biol. Chem. , vol.271 , pp. 563-577
    • Soltoff, S.P.1    Cantley, L.C.2
  • 95
    • 0029043786 scopus 로고
    • Tyrosine phosphorylation and translocation of the c-Cbl protein after activation of tyrosine kinase signaling pathways
    • Tanaka, S., L. Neff, R. Baron, and J. B. Levy: Tyrosine phosphorylation and translocation of the c-Cbl protein after activation of tyrosine kinase signaling pathways. J. Biol. Chem., 270:14347-14351 (1995).
    • (1995) J. Biol. Chem. , vol.270 , pp. 14347-14351
    • Tanaka, S.1    Neff, L.2    Baron, R.3    Levy, J.B.4
  • 96
    • 0029670779 scopus 로고    scopus 로고
    • Physical and functional association of the Cbl protooncogene product with an Src-family protein tyrosine kinase, p53/561yn, in the B cell antigen receptor-mediated signaling
    • Tezuka, T., H. Umemori, N. Fusaki, T. Yagi, M. Takata, T. Kurosaki, and T. Yamamoto: Physical and functional association of the Cbl protooncogene product with an Src-family protein tyrosine kinase, p53/561yn, in the B cell antigen receptor-mediated signaling. J. Exp. Med., 183:675-680 (1996).
    • (1996) J. Exp. Med. , vol.183 , pp. 675-680
    • Tezuka, T.1    Umemori, H.2    Fusaki, N.3    Yagi, T.4    Takata, M.5    Kurosaki, T.6    Yamamoto, T.7
  • 97
    • 0031011155 scopus 로고    scopus 로고
    • EOF receptor binding and transformation by v-cbl is ablated by the introduction of a loss-of-function mutation from the Caenorhabditis elegans Sli-1 gene
    • Thien, C. B. F. and W. Y. Langdon: EOF receptor binding and transformation by v-cbl is ablated by the introduction of a loss-of-function mutation from the Caenorhabditis elegans Sli-1 gene. Oncogene, 14:2239-2249 (1997a).
    • (1997) Oncogene , vol.14 , pp. 2239-2249
    • Thien, C.B.F.1    Langdon, W.Y.2
  • 98
    • 0031455765 scopus 로고    scopus 로고
    • Tyrosine kinase activity of the EGF receptor is enhanced by the expression of oncogenic 70Z-Cbl
    • Thien, C. B. F. and W. Y. Langdon: Tyrosine kinase activity of the EGF receptor is enhanced by the expression of oncogenic 70Z-Cbl. Oncogene, 15:2909-2919 (1997b).
    • (1997) Oncogene , vol.15 , pp. 2909-2919
    • Thien, C.B.F.1    Langdon, W.Y.2
  • 99
    • 0029998597 scopus 로고    scopus 로고
    • Specific association of tyrosine phosphorylated c-Cbl with Fyn tyrosine kinase in T cells
    • Tsygankov, A. Y., S. Mahajan, J. E. Fincke, and J. B. Bolen: Specific association of tyrosine phosphorylated c-Cbl with Fyn tyrosine kinase in T cells. J. Biol. Chem., 271:27130-27137 (1996).
    • (1996) J. Biol. Chem. , vol.271 , pp. 27130-27137
    • Tsygankov, A.Y.1    Mahajan, S.2    Fincke, J.E.3    Bolen, J.B.4
  • 100
    • 0025245816 scopus 로고
    • A physical linkage group in human chromosome band 1 1q23 covering a region implicated in leukocyte neoplasia
    • Tunnacliffe, A. and R. S. McGuire: A physical linkage group in human chromosome band 1 1q23 covering a region implicated in leukocyte neoplasia. Genomics, 8:447-453 (1990).
    • (1990) Genomics , vol.8 , pp. 447-453
    • Tunnacliffe, A.1    McGuire, R.S.2
  • 101
    • 0030598824 scopus 로고    scopus 로고
    • Interaction of the c-cbl protooncogene product with the Tyk-2 protein tyrosine kinase
    • Uddin, S., C. Cardziola, A. Dangat, T. Yi, and L. C. Platanias: Interaction of the c-cbl protooncogene product with the Tyk-2 protein tyrosine kinase. Biochem. Biophys. Res. Comm., 225:833-838 (1996).
    • (1996) Biochem. Biophys. Res. Comm. , vol.225 , pp. 833-838
    • Uddin, S.1    Cardziola, C.2    Dangat, A.3    Yi, T.4    Platanias, L.C.5
  • 102
    • 0030935791 scopus 로고    scopus 로고
    • Antisense repression of protooncogene c-Cbl enhances activation of the Jak-Stat pathway but not the Ras pathway in epidermal growth factor receptor signaling
    • Ueno, H., K. Sasaki, K. Miyagawa, H. Honda, K. Mitani, Y. Yazaki, and H. Hirai: Antisense repression of protooncogene c-Cbl enhances activation of the Jak-Stat pathway but not the Ras pathway in epidermal growth factor receptor signaling. J. Biol. Chem., 272:8739-8743 (1997).
    • (1997) J. Biol. Chem. , vol.272 , pp. 8739-8743
    • Ueno, H.1    Sasaki, K.2    Miyagawa, K.3    Honda, H.4    Mitani, K.5    Yazaki, Y.6    Hirai, H.7
  • 103
    • 0030058105 scopus 로고    scopus 로고
    • C-Cbl is transiently tyrosine-phosphorylated, ubiquitinated, and membrane-targeted following CSF-1 Stimulation of macrophages
    • Wang, Y., Y. G. Yeung, W. Y. Langdon, and E. R. Stanley: c-Cbl is transiently tyrosine-phosphorylated, ubiquitinated, and membrane-targeted following CSF-1 Stimulation of macrophages. J. Biol. Chem., 271:17-20 (1996).
    • (1996) J. Biol. Chem. , vol.271 , pp. 17-20
    • Wang, Y.1    Yeung, Y.G.2    Langdon, W.Y.3    Stanley, E.R.4
  • 104
    • 0028950637 scopus 로고
    • Insulin-stimulated disassociation of the SOS-Grb2 complex
    • Waters, S. B., K. Yamauchi, and J. E. Pessin: Insulin-stimulated disassociation of the SOS-Grb2 complex. Mol. Cell. Biol., 15:2791-2799 (1995).
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2791-2799
    • Waters, S.B.1    Yamauchi, K.2    Pessin, J.E.3
  • 105
    • 0028033527 scopus 로고    scopus 로고
    • B cell antigen receptor stimulation activates the human Bruton's tyrosine kinase, which is deficient in X-linked Agammaglobulinemia
    • de Weers, M., G. S. Brouns, S. Hinshelwood, C. Kinnon, R. K. B. Schuurman, R. W. Hendriks, and J. Borst: B cell antigen receptor stimulation activates the human Bruton's tyrosine kinase, which is deficient in X-linked Agammaglobulinemia. J. Biol. Chem., 269:23857-23860 (1996).
    • (1996) J. Biol. Chem. , vol.269 , pp. 23857-23860
    • De Weers, M.1    Brouns, G.S.2    Hinshelwood, S.3    Kinnon, C.4    Schuurman, R.K.B.5    Hendriks, R.W.6    Borst, J.7
  • 106
    • 0028014460 scopus 로고
    • Signal transduction by lymphocyte antigen receptors
    • Weiss, A. and D. R. Littman: Signal transduction by lymphocyte antigen receptors. Cell, 76:263-274 (1994).
    • (1994) Cell , vol.76 , pp. 263-274
    • Weiss, A.1    Littman, D.R.2
  • 107
    • 0029740513 scopus 로고    scopus 로고
    • C-kit ligand stimulates tyrosine phosphorylation of the c-Cbl protein in human hematopoietic cells
    • Wisniewski, D., A. Strife, and B. Clarkson: c-kit ligand stimulates tyrosine phosphorylation of the c-Cbl protein in human hematopoietic cells. Leukemia, 10:1436-1442 (1996).
    • (1996) Leukemia , vol.10 , pp. 1436-1442
    • Wisniewski, D.1    Strife, A.2    Clarkson, B.3
  • 109
    • 0029124883 scopus 로고
    • Similarity of sli-1, a regulator of vulval development in C. elegans to the mammalian protooncogene c-Cbl
    • Yoon, C. H., J. Lee, G. D. Jongeward, and P. W. Sternberg: Similarity of sli-1, a regulator of vulval development in C. elegans to the mammalian protooncogene c-Cbl. Science, 269:1102-1105 (1995).
    • (1995) Science , vol.269 , pp. 1102-1105
    • Yoon, C.H.1    Lee, J.2    Jongeward, G.D.3    Sternberg, P.W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.