-
1
-
-
0025232430
-
Parkinson's disease
-
Marsden CD. Parkinson's disease. Lancet 1990;335:908-952
-
(1990)
Lancet
, vol.335
, pp. 908-952
-
-
Marsden, C.D.1
-
2
-
-
0025893945
-
Parkinson's disease: Pathophysiology
-
Agid Y. Parkinson's disease: pathophysiology. Lancet 1991;337: 1321-1324
-
(1991)
Lancet
, vol.337
, pp. 1321-1324
-
-
Agid, Y.1
-
4
-
-
0019160120
-
Non-aminergic striatal neurons convert exogenous L-dopa to dopamine in parkinsonism
-
Melamed E, Hefti F, Wurtman RH. Non-aminergic striatal neurons convert exogenous L-dopa to dopamine in parkinsonism. Ann Neurol 1980;8:528-536
-
(1980)
Ann Neurol
, vol.8
, pp. 528-536
-
-
Melamed, E.1
Hefti, F.2
Wurtman, R.H.3
-
5
-
-
0000354430
-
L-dopa's mechanism of action in Parkinson's disease
-
Hefti F, Melamed E. L-dopa's mechanism of action in Parkinson's disease. Trends Neurosci 1980;3:229-231
-
(1980)
Trends Neurosci
, vol.3
, pp. 229-231
-
-
Hefti, F.1
Melamed, E.2
-
6
-
-
0345324749
-
Mechanism of action of exogenous L-dopa: Is it a physiological therapy for Parkinson's disease?
-
Jankovic J, Tolosa E, eds. Baltimore: Urban and Schwarzenberg
-
Melamed E. Mechanism of action of exogenous L-dopa: Is it a physiological therapy for Parkinson's disease? In: Jankovic J, Tolosa E, eds. Advances in Parkinson's disease and movement disorders. Baltimore: Urban and Schwarzenberg, 1988:87-97
-
(1988)
Advances in Parkinson's Disease and Movement Disorders
, pp. 87-97
-
-
Melamed, E.1
-
7
-
-
0026552595
-
Biochemical and functional differences between dopamine formed from endogenous tyrosine and exogenous L-dopa in nigro-striatal dopaminergic neurons
-
Melamed E. Biochemical and functional differences between dopamine formed from endogenous tyrosine and exogenous L-dopa in nigro-striatal dopaminergic neurons. Neurochem Int 1992;20(Suppl):115-117
-
(1992)
Neurochem Int
, vol.20
, Issue.SUPPL.
, pp. 115-117
-
-
Melamed, E.1
-
8
-
-
0029775677
-
Is levodopa toxic?
-
Fahn S. Is levodopa toxic? Neurology 1996;47(Suppl):S184-195
-
(1996)
Neurology
, vol.47
, Issue.SUPPL.
-
-
Fahn, S.1
-
9
-
-
0021234640
-
Should levodopa therapy for parkinsonism be started early or late? Evidence against early treatment
-
Fahn S, Bressman SB. Should levodopa therapy for parkinsonism be started early or late? Evidence against early treatment. Can J Neurol Sci 1984;11:200-206
-
(1984)
Can J Neurol Sci
, vol.11
, pp. 200-206
-
-
Fahn, S.1
Bressman, S.B.2
-
10
-
-
0021278775
-
Chronic low dose levodopa therapy in Parkinson's disease: An argument for delaying L-dopa therapy
-
Rajput AH, Stern W, Laverty WH. Chronic low dose levodopa therapy in Parkinson's disease: an argument for delaying L-dopa therapy. Neurology 1984;34:991-996
-
(1984)
Neurology
, vol.34
, pp. 991-996
-
-
Rajput, A.H.1
Stern, W.2
Laverty, W.H.3
-
11
-
-
0022627693
-
Initiation of levodopa therapy in parkinsonian patients should be delayed until the advanced stages of the disease
-
Melamed E. Initiation of levodopa therapy in parkinsonian patients should be delayed until the advanced stages of the disease. Arch Neurol 1986;43:402-405
-
(1986)
Arch Neurol
, vol.43
, pp. 402-405
-
-
Melamed, E.1
-
12
-
-
0028965017
-
A case against early levodopa treatment of Parkinson's disease
-
Quinn NP. A case against early levodopa treatment of Parkinson's disease. Clin Neuropharmacol 1994;17:S43-49
-
(1994)
Clin Neuropharmacol
, vol.17
-
-
Quinn, N.P.1
-
13
-
-
0017785767
-
L-dopa: Selective toxiciry for melanoma cells in vitro
-
Wick MM, Byers L, Frei E. L-dopa: selective toxiciry for melanoma cells in vitro. Science 1977;197:468-469
-
(1977)
Science
, vol.197
, pp. 468-469
-
-
Wick, M.M.1
Byers, L.2
Frei, E.3
-
14
-
-
0026061854
-
Dopa and dopamine cause cultured neuronal death in the presence of iron
-
Tanaka M, Sotomatsu A, Kanai H, Hirai S. Dopa and dopamine cause cultured neuronal death in the presence of iron. J Neurol Sci 1991;101:198-203
-
(1991)
J Neurol Sci
, vol.101
, pp. 198-203
-
-
Tanaka, M.1
Sotomatsu, A.2
Kanai, H.3
Hirai, S.4
-
15
-
-
0026531427
-
Neurotoxicity of levodopa on catecholamine rich neurons
-
Mena MA, Pardo B, Casarejos MJ, Fahn S, de Yebenes JG. Neurotoxicity of levodopa on catecholamine rich neurons. Mov Disord 1992;7:23-31
-
(1992)
Mov Disord
, vol.7
, pp. 23-31
-
-
Mena, M.A.1
Pardo, B.2
Casarejos, M.J.3
Fahn, S.4
De Yebenes, J.G.5
-
16
-
-
0018148688
-
Autooxidation versus covalent binding of quinones as the mechanism of toxicity of dopamine, 6-hydroxydopamine and related compounds towards C1300 neuroblastoma cells in vitro
-
Graham DJ, Tiffany SM, Bell WR, Gutknecht WF. Autooxidation versus covalent binding of quinones as the mechanism of toxicity of dopamine, 6-hydroxydopamine and related compounds towards C1300 neuroblastoma cells in vitro. Mol Pharmacol 1978;14:644-653
-
(1978)
Mol Pharmacol
, vol.14
, pp. 644-653
-
-
Graham, D.J.1
Tiffany, S.M.2
Bell, W.R.3
Gutknecht, W.F.4
-
17
-
-
0028988351
-
Iron-mediated oxidation of 3,4-dihydroxyphenylalanine to an excitotoxin
-
Newcomer TA, Rosenberg PA, Aizenman E. Iron-mediated oxidation of 3,4-dihydroxyphenylalanine to an excitotoxin. J Neurochem 1995;64:1742-1748
-
(1995)
J Neurochem
, vol.64
, pp. 1742-1748
-
-
Newcomer, T.A.1
Rosenberg, P.A.2
Aizenman, E.3
-
18
-
-
0018095085
-
Oxidative pathways for catecholamines in the genesis of neuromelanin and cytotoxic quinones
-
Graham AG. Oxidative pathways for catecholamines in the genesis of neuromelanin and cytotoxic quinones. Mol Pharmacol 1978;14:633-643
-
(1978)
Mol Pharmacol
, vol.14
, pp. 633-643
-
-
Graham, A.G.1
-
19
-
-
0027268723
-
Ascorbic acid protecrs against levodopa-induced neurotoxicity on a catecholamine-rich human neuroblastoma cell line
-
Pardo B, Mena MA, Fahn S, de Yebenes JG. Ascorbic acid protecrs against levodopa-induced neurotoxicity on a catecholamine-rich human neuroblastoma cell line. Mov Disord 1993;8:278-284
-
(1993)
Mov Disord
, vol.8
, pp. 278-284
-
-
Pardo, B.1
Mena, M.A.2
Fahn, S.3
De Yebenes, J.G.4
-
20
-
-
0027462802
-
Levodopa toxicity in fetal rat midbrain neurons in culture: Modulation by ascorbic acid
-
Mena MA, Pardo B, Paino CL, de Yebenes JG. Levodopa toxicity in fetal rat midbrain neurons in culture: modulation by ascorbic acid. Neuroreport 1993;4:438-440
-
(1993)
Neuroreport
, vol.4
, pp. 438-440
-
-
Mena, M.A.1
Pardo, B.2
Paino, C.L.3
De Yebenes, J.G.4
-
21
-
-
0028834192
-
L-dopa cytotoxicity to PC-12 cells in culture is via its auto-oxidation
-
Basma AN, Morris EJ, Nicklas WJ, Geller HM. L-dopa cytotoxicity to PC-12 cells in culture is via its auto-oxidation. J Neurochem 1995;64:825-832
-
(1995)
J Neurochem
, vol.64
, pp. 825-832
-
-
Basma, A.N.1
Morris, E.J.2
Nicklas, W.J.3
Geller, H.M.4
-
22
-
-
0029053242
-
Toxic effects of L-dopa in mesencephalic cell cultures: Protection with anti-oxidants
-
Pardo B, Mena MA, Casarejos MJ, Paino CL, de Yebenes JG. Toxic effects of L-dopa in mesencephalic cell cultures: protection with anti-oxidants. Brain Res 1995;682:133-143
-
(1995)
Brain Res
, vol.682
, pp. 133-143
-
-
Pardo, B.1
Mena, M.A.2
Casarejos, M.J.3
Paino, C.L.4
De Yebenes, J.G.5
-
23
-
-
0029009569
-
Lipid peroxidation in brain: Interactions of L-dopa/dopamine with ascorbate and iron
-
Li CL, Werner P, Cohen G. Lipid peroxidation in brain: interactions of L-dopa/dopamine with ascorbate and iron. Neurodegeneration 1995;4:147-153
-
(1995)
Neurodegeneration
, vol.4
, pp. 147-153
-
-
Li, C.L.1
Werner, P.2
Cohen, G.3
-
24
-
-
0027487511
-
Chronic levodopa administration alters cerebral mitochondrial respiratory chain activity
-
Przedborski S, Jackson-Lewis V, Muthane U, et al. Chronic levodopa administration alters cerebral mitochondrial respiratory chain activity. Ann Neurol 1993;34:715-723
-
(1993)
Ann Neurol
, vol.34
, pp. 715-723
-
-
Przedborski, S.1
Jackson-Lewis, V.2
Muthane, U.3
-
25
-
-
0029005237
-
Antiparkinsonian therapies and brain mirochondrial complex I activity
-
Przedborski S, Jackson-Lewis V, Fahn S. Antiparkinsonian therapies and brain mirochondrial complex I activity. Mov Disord 1995;10:312-317
-
(1995)
Mov Disord
, vol.10
, pp. 312-317
-
-
Przedborski, S.1
Jackson-Lewis, V.2
Fahn, S.3
-
26
-
-
0028857498
-
L-dopa inhibits complex IV of the electron transport chain in catecholamine-rich human neuroblastoma NB69 cells
-
Pardo B, Mena MA, de Yebenes JG. L-dopa inhibits complex IV of the electron transport chain in catecholamine-rich human neuroblastoma NB69 cells. J Neurochem 1995;64:576-582
-
(1995)
J Neurochem
, vol.64
, pp. 576-582
-
-
Pardo, B.1
Mena, M.A.2
De Yebenes, J.G.3
-
27
-
-
0028081018
-
Intense oxidative DNA damage promoted by L-dopa and its metabolites: Implications for neurodegenerative disease
-
Spencer JP, Jenner A, Arumoa OI, Marsden CD, Halliwell B. Intense oxidative DNA damage promoted by L-dopa and its metabolites: implications for neurodegenerative disease. FEBS Lett 1994;353:246-250
-
(1994)
FEBS Lett
, vol.353
, pp. 246-250
-
-
Spencer, J.P.1
Jenner, A.2
Arumoa, O.I.3
Marsden, C.D.4
Halliwell, B.5
-
28
-
-
0024340065
-
Levodopa/dopamine analogs as inhibitors of DNA synthesis in human melanoma cells
-
Wick MM. Levodopa/dopamine analogs as inhibitors of DNA synthesis in human melanoma cells. J Invest Dermatol 1989; 92:329S-331S
-
(1989)
J Invest Dermatol
, vol.92
-
-
Wick, M.M.1
-
29
-
-
0025063462
-
Toxicity of 6-hydroxydopamine and dopamine for dopaminergic neurons in culture
-
Michel PP, Hefti F. Toxicity of 6-hydroxydopamine and dopamine for dopaminergic neurons in culture. J Neurosci Res 1990;26:428-435
-
(1990)
J Neurosci Res
, vol.26
, pp. 428-435
-
-
Michel, P.P.1
Hefti, F.2
-
30
-
-
0030977070
-
Comparison of neurotoxicity following repeated administration of L-dopa, D-dopa and dopamine to embryonic mesencephalic dopamine neurons in cultures derived from Fischer 344 and Sprague-Dawley donors
-
Alexander T, Sortwell CE, Sladek CD, Roth RH, Steece-Collier K. Comparison of neurotoxicity following repeated administration of L-dopa, D-dopa and dopamine to embryonic mesencephalic dopamine neurons in cultures derived from Fischer 344 and Sprague-Dawley donors. Cell Transplant 1997;6:309-315
-
(1997)
Cell Transplant
, vol.6
, pp. 309-315
-
-
Alexander, T.1
Sortwell, C.E.2
Sladek, C.D.3
Roth, R.H.4
Steece-Collier, K.5
-
32
-
-
0027411586
-
Apoptosis: Suicide, execution or murder?
-
Martin SJ. Apoptosis: suicide, execution or murder? Trends Cell Biol 1993;3:141-144
-
(1993)
Trends Cell Biol
, vol.3
, pp. 141-144
-
-
Martin, S.J.1
-
33
-
-
0027513268
-
Apoptosis
-
Cohen JJ. Apoptosis. Immunol Today 1993;14:126-130
-
(1993)
Immunol Today
, vol.14
, pp. 126-130
-
-
Cohen, J.J.1
-
34
-
-
0028198186
-
Dopamine induces apoptosis-like cell death in cultured chick sympathetic neurons - A possible novel pathogentic mechanism in Parkinson's disease
-
Ziv I, Melamed E, Nardi N, et al. Dopamine induces apoptosis-like cell death in cultured chick sympathetic neurons - a possible novel pathogentic mechanism in Parkinson's disease. Neurosci Lett 1994;170:136-140
-
(1994)
Neurosci Lett
, vol.170
, pp. 136-140
-
-
Ziv, I.1
Melamed, E.2
Nardi, N.3
-
35
-
-
0028978931
-
Dopamine-induced programmed cell death in mouse thymocytes
-
Offen D, Ziv I, Gordin S, Malik Z, Barzilai A, Melamed E. Dopamine-induced programmed cell death in mouse thymocytes. Biochim Biophys Acta 1995;1268:171-177
-
(1995)
Biochim Biophys Acta
, vol.1268
, pp. 171-177
-
-
Offen, D.1
Ziv, I.2
Gordin, S.3
Malik, Z.4
Barzilai, A.5
Melamed, E.6
-
36
-
-
0031053186
-
Monoamine-induced apoptotic neuronal cell death
-
Zilkha-Falb R, Ziv I, Nardi N, Offen D, Melamed E, Barzilai A. Monoamine-induced apoptotic neuronal cell death. Cell Mol Neurobiol 1997;7:110-118
-
(1997)
Cell Mol Neurobiol
, vol.7
, pp. 110-118
-
-
Zilkha-Falb, R.1
Ziv, I.2
Nardi, N.3
Offen, D.4
Melamed, E.5
Barzilai, A.6
-
37
-
-
0030249286
-
Prevention of dopamine-induced cell death by thiol antioxidants: Possible implication for treatment of Parkinson's disease
-
Offen D, Sternin H, Ziv I, Melamed E, Hochman A. Prevention of dopamine-induced cell death by thiol antioxidants: possible implication for treatment of Parkinson's disease. Exp Neurol 1996;141:32-39
-
(1996)
Exp Neurol
, vol.141
, pp. 32-39
-
-
Offen, D.1
Sternin, H.2
Ziv, I.3
Melamed, E.4
Hochman, A.5
-
38
-
-
0001392257
-
The proto-oncogene bcl-2 inhibits cellular toxicity of dopamine: Possible implications for Parkinson's disease
-
Ziv I, Offen D, Haviv R, et al. The proto-oncogene bcl-2 inhibits cellular toxicity of dopamine: possible implications for Parkinson's disease. Apoptosis 1997;2:149-155
-
(1997)
Apoptosis
, vol.2
, pp. 149-155
-
-
Ziv, I.1
Offen, D.2
Haviv, R.3
-
39
-
-
0029942337
-
Histochemical detection of apoptosis in Parkinson's disease
-
Mochizuki H, Goto K, Mori H, Mizuno Y. Histochemical detection of apoptosis in Parkinson's disease. J Neurol Sci 1996; 137:120-123
-
(1996)
J Neurol Sci
, vol.137
, pp. 120-123
-
-
Mochizuki, H.1
Goto, K.2
Mori, H.3
Mizuno, Y.4
-
40
-
-
0031036896
-
Apoptosis and autophagy in nigral neurons of patients with Parkinson's disease
-
Anglade P, Vyas S, Javoy-Agid F, et al. Apoptosis and autophagy in nigral neurons of patients with Parkinson's disease. Histoi Histopathol 1997;12:25-31
-
(1997)
Histoi Histopathol
, vol.12
, pp. 25-31
-
-
Anglade, P.1
Vyas, S.2
Javoy-Agid, F.3
-
41
-
-
0031013141
-
Apoptotic-like changes in Lewy body-associated disorders and normal aging in substantia nigral neurons
-
Tompkins MM, Basgall EJ, Zamvini E, Hill WD. Apoptotic-like changes in Lewy body-associated disorders and normal aging in substantia nigral neurons. Am J Pathol 1997;150:119-131
-
(1997)
Am J Pathol
, vol.150
, pp. 119-131
-
-
Tompkins, M.M.1
Basgall, E.J.2
Zamvini, E.3
Hill, W.D.4
-
42
-
-
1842297607
-
On the question of apoptosis in rhe parkinsonian substantia nigra
-
Berl
-
Kosel S, Egensperger R, von Eitzen U, Mehraein P, Graeber MB. On the question of apoptosis in rhe parkinsonian substantia nigra. Acta Neuropathol (Berl) 1997;93:105-108
-
(1997)
Acta Neuropathol
, vol.93
, pp. 105-108
-
-
Kosel, S.1
Egensperger, R.2
Von Eitzen, U.3
Mehraein, P.4
Graeber, M.B.5
-
43
-
-
0026484388
-
The oxidant stress hypothesis in Parkinson's disease. Evidence supporting it
-
Fahn S, Cohen G. The oxidant stress hypothesis in Parkinson's disease. Evidence supporting it. Ann Neurol 1992;32:804-812
-
(1992)
Ann Neurol
, vol.32
, pp. 804-812
-
-
Fahn, S.1
Cohen, G.2
-
44
-
-
0027496238
-
A radical hypothesis for neurodegeneration
-
Olanow CW. A radical hypothesis for neurodegeneration. Trends Neurosci 1993;16:439-444
-
(1993)
Trends Neurosci
, vol.16
, pp. 439-444
-
-
Olanow, C.W.1
-
45
-
-
0026635461
-
Oxidative stress as a cause of nigral cell death in Parkinson's disease and incidental Lewy body disease
-
Jenner P, Dexter DT, Sian J, Schapira AHV, Marsden CD. Oxidative stress as a cause of nigral cell death in Parkinson's disease and incidental Lewy body disease. Ann Neurol 1992;32: S82-S87
-
(1992)
Ann Neurol
, vol.32
-
-
Jenner, P.1
Dexter, D.T.2
Sian, J.3
Schapira, A.H.V.4
Marsden, C.D.5
-
46
-
-
0031023430
-
Levodopa induces apoptosis in cultured neuronal cells - A possible accelerator of nigrostriatal degeneration in Parkinson's disease?
-
Ziv I, Zilkha-Falb R, Offen D, Shirvan A, Barzilai A, Melamed E. Levodopa induces apoptosis in cultured neuronal cells - a possible accelerator of nigrostriatal degeneration in Parkinson's disease? Mov Disord 1997;12:17-23
-
(1997)
Mov Disord
, vol.12
, pp. 17-23
-
-
Ziv, I.1
Zilkha-Falb, R.2
Offen, D.3
Shirvan, A.4
Barzilai, A.5
Melamed, E.6
-
47
-
-
0029051317
-
Induction of apoptosis in catecholaminergic PC-12 cells by L-dopa. Implications for the treatment of Parkinson's disease
-
Walkinshaw G, Waters CM. Induction of apoptosis in catecholaminergic PC-12 cells by L-dopa. Implications for the treatment of Parkinson's disease. J Clin Invest 1995;95:2458-2464
-
(1995)
J Clin Invest
, vol.95
, pp. 2458-2464
-
-
Walkinshaw, G.1
Waters, C.M.2
-
48
-
-
0019447228
-
Long-term administration of L-dopa does not damage dopaminergic neurons in the mouse
-
Hefti F, Melamed E, Bhawan J, Wurtman RJ. Long-term administration of L-dopa does not damage dopaminergic neurons in the mouse. Neurology 1981;31:1194-1195
-
(1981)
Neurology
, vol.31
, pp. 1194-1195
-
-
Hefti, F.1
Melamed, E.2
Bhawan, J.3
Wurtman, R.J.4
-
49
-
-
0021129038
-
Nigrostriatal dopaminergic neurons remain undamaged in rats given high doses of L-dopa and carbidopa chronically
-
Perry TL, Yong VW, Ito U, et al. Nigrostriatal dopaminergic neurons remain undamaged in rats given high doses of L-dopa and carbidopa chronically. J Neurochem 1984;43:990-993
-
(1984)
J Neurochem
, vol.43
, pp. 990-993
-
-
Perry, T.L.1
Yong, V.W.2
Ito, U.3
-
50
-
-
0028972930
-
Acute L-dopa pretreatment potentiates 6-hydroxydopamine-induced toxic effects on nigrostriatal dopaminergic neurons in mice
-
Naudin B, Bonnet JJ, Costentin J. Acute L-dopa pretreatment potentiates 6-hydroxydopamine-induced toxic effects on nigrostriatal dopaminergic neurons in mice. Brain Res 1995;701: 151-157
-
(1995)
Brain Res
, vol.701
, pp. 151-157
-
-
Naudin, B.1
Bonnet, J.J.2
Costentin, J.3
-
51
-
-
0027287928
-
Suppressive effect of L-dopa on dopamine cells remaining in the ventral tegmental area of rats previously exposed to the neurotoxin 6-hydroxydopamine
-
Blunt SB, Jenner P, Marsden CD. Suppressive effect of L-dopa on dopamine cells remaining in the ventral tegmental area of rats previously exposed to the neurotoxin 6-hydroxydopamine. Mov Disord 1993;8:129-133
-
(1993)
Mov Disord
, vol.8
, pp. 129-133
-
-
Blunt, S.B.1
Jenner, P.2
Marsden, C.D.3
-
52
-
-
0028343897
-
Differential effects of chronic L-dopa treatment on lipid peroxidation in the mouse brain with and without pretreatment with 6-hydroxydopamine
-
Ogawa N, Aganuma M, Kondo Y, Yamamoto M, Mori A. Differential effects of chronic L-dopa treatment on lipid peroxidation in the mouse brain with and without pretreatment with 6-hydroxydopamine. Neurosci Lett 1994;171:55-58
-
(1994)
Neurosci Lett
, vol.171
, pp. 55-58
-
-
Ogawa, N.1
Aganuma, M.2
Kondo, Y.3
Yamamoto, M.4
Mori, A.5
-
53
-
-
0030901296
-
Absence of neurotoxicity of chronic L-dopa treatment in 6-hydroxydopamine-lesioned rats
-
Dziewczapolski G, Murer G, Agid Y, Gershanik O, Raisman-Vozari R. Absence of neurotoxicity of chronic L-dopa treatment in 6-hydroxydopamine-lesioned rats. Neuroreport 1997;8:975-979
-
(1997)
Neuroreport
, vol.8
, pp. 975-979
-
-
Dziewczapolski, G.1
Murer, G.2
Agid, Y.3
Gershanik, O.4
Raisman-Vozari, R.5
-
54
-
-
0342425519
-
Can chronic levodopa therapy accelerate degeneration of dopaminergic neurons and progression of Parkinson's disease?
-
Nagatsu T, Fisher A, Yoshida M, eds. New York: Plenum Press
-
Melamed E, Rosenthal J. Can chronic levodopa therapy accelerate degeneration of dopaminergic neurons and progression of Parkinson's disease? In: Nagatsu T, Fisher A, Yoshida M, eds. Basic clinical and therapeutic aspects of Alzheimer's and Parkinson's diseases. New York: Plenum Press, 1990;253-256
-
(1990)
Basic Clinical and Therapeutic Aspects of Alzheimer's and Parkinson's Diseases
, pp. 253-256
-
-
Melamed, E.1
Rosenthal, J.2
-
55
-
-
0025245453
-
Chronic levodopa impairs morphological development of grafted embryonic dopamine neurons
-
Steece-Collier K, Collier TJ, Sladeck CD, Sladeck JR. Chronic levodopa impairs morphological development of grafted embryonic dopamine neurons. Exp Neurol 1990;110:201-208
-
(1990)
Exp Neurol
, vol.110
, pp. 201-208
-
-
Steece-Collier, K.1
Collier, T.J.2
Sladeck, C.D.3
Sladeck, J.R.4
-
57
-
-
0345311137
-
Prenatal administration of levodopa is not toxic to fetal dopaminergic neurons in vivo
-
Melamed E, Rosenthal J, Reches H. Prenatal administration of levodopa is not toxic to fetal dopaminergic neurons in vivo. Neurology 1992;42(Suppl 3):378
-
(1992)
Neurology
, vol.42
, Issue.3 SUPPL.
, pp. 378
-
-
Melamed, E.1
Rosenthal, J.2
Reches, H.3
-
58
-
-
0022946382
-
Preservation of the substantia nigra and locus ceruleus in a patient receiving levodopa (2 kg) plus decarboxylasc inhibitor over a four year period
-
Quinn N, Parkes D, Janota I, Marsden CD. Preservation of the substantia nigra and locus ceruleus in a patient receiving levodopa (2 kg) plus decarboxylasc inhibitor over a four year period. Mov Disord 1986;1:65-68
-
(1986)
Mov Disord
, vol.1
, pp. 65-68
-
-
Quinn, N.1
Parkes, D.2
Janota, I.3
Marsden, C.D.4
-
60
-
-
0028911848
-
Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's disease
-
Kordower JH, Freeman TB, Snow BJ, Olanow CW. Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's disease. N Engl J Med 1995;332:1118-1124
-
(1995)
N Engl J Med
, vol.332
, pp. 1118-1124
-
-
Kordower, J.H.1
Freeman, T.B.2
Snow, B.J.3
Olanow, C.W.4
-
61
-
-
0023802240
-
Does levodopa aggravate Parkinson's disease?
-
Blin J, Bonnet AM, Agid Y. Does levodopa aggravate Parkinson's disease? Neurology 1988;38:1410-1416
-
(1988)
Neurology
, vol.38
, pp. 1410-1416
-
-
Blin, J.1
Bonnet, A.M.2
Agid, Y.3
-
62
-
-
0031194653
-
Calretinin-immunoreactive dopaminergic neurons from embryonic rat mesencephalon are resistant to levodopa-induced neurotoxicity
-
Isaacs KR, Wolpoe ME, Jacobowitz DM. Calretinin-immunoreactive dopaminergic neurons from embryonic rat mesencephalon are resistant to levodopa-induced neurotoxicity. Exp Neurol 1997;146:25-32
-
(1997)
Exp Neurol
, vol.146
, pp. 25-32
-
-
Isaacs, K.R.1
Wolpoe, M.E.2
Jacobowitz, D.M.3
-
63
-
-
0028040019
-
Bcl-2 and the regulation of programmed cell death
-
Reed JC. Bcl-2 and the regulation of programmed cell death. J Cell Biol 1994;124:1-6
-
(1994)
J Cell Biol
, vol.124
, pp. 1-6
-
-
Reed, J.C.1
-
64
-
-
0027945731
-
The bcl-2 family of proteins: Regulators of cell death and survival
-
Munez G, Clarke MF. The bcl-2 family of proteins: regulators of cell death and survival. Trends Cell Biol 1994;4:399-403
-
(1994)
Trends Cell Biol
, vol.4
, pp. 399-403
-
-
Munez, G.1
Clarke, M.F.2
-
65
-
-
3543130533
-
Dopamine-induced apoprosis is inhibited in PC12 cells expressing bcl-2: Evidence rhar the proto-oncogene may act as an antioxidant
-
Offen D, Ziv I, Panet H, Wasserman L, Stein R, Melamed E, Barzilai A. Dopamine-induced apoprosis is inhibited in PC12 cells expressing bcl-2: evidence rhar the proto-oncogene may act as an antioxidant. Cell Mol Neurobiol 1997;17:285-304
-
(1997)
Cell Mol Neurobiol
, vol.17
, pp. 285-304
-
-
Offen, D.1
Ziv, I.2
Panet, H.3
Wasserman, L.4
Stein, R.5
Melamed, E.6
Barzilai, A.7
-
66
-
-
0030572714
-
Bcl-2 protein is increased in the brain from parkinsonian patients
-
Mogi M, Harada M, Kondo T, et al. Bcl-2 protein is increased in the brain from parkinsonian patients. Neurosci Lett 1996; 215:137-139
-
(1996)
Neurosci Lett
, vol.215
, pp. 137-139
-
-
Mogi, M.1
Harada, M.2
Kondo, T.3
-
67
-
-
0029915162
-
Glia conditioned medium protects fetal rat midbrain neurons in culture from L-dopa toxicity
-
Mena MA, Casarejos MJ, Carazo A, Paino CL, de Yebenes GJ. Glia conditioned medium protects fetal rat midbrain neurons in culture from L-dopa toxicity. Neuroreport 1996;7:441-449
-
(1996)
Neuroreport
, vol.7
, pp. 441-449
-
-
Mena, M.A.1
Casarejos, M.J.2
Carazo, A.3
Paino, C.L.4
De Yebenes, G.J.5
-
68
-
-
0025869874
-
Temporal relationships between plasma and cerebrospinal fluid pharmacokinetics of levodopa and clinical effect in Parkinson's disease
-
Olanow CW, Gauger BA, Cederbaum JM. Temporal relationships between plasma and cerebrospinal fluid pharmacokinetics of levodopa and clinical effect in Parkinson's disease. Ann Neurol 1991;29:556-559
-
(1991)
Ann Neurol
, vol.29
, pp. 556-559
-
-
Olanow, C.W.1
Gauger, B.A.2
Cederbaum, J.M.3
-
69
-
-
0030841599
-
Central levodopa metabolism in Parkinson's disease after administration of stable isotope-labeled levodopa
-
Durso R, Evans JE, Josephs E, et al. Central levodopa metabolism in Parkinson's disease after administration of stable isotope-labeled levodopa. Ann Neurol 1997;42:300-304
-
(1997)
Ann Neurol
, vol.42
, pp. 300-304
-
-
Durso, R.1
Evans, J.E.2
Josephs, E.3
-
70
-
-
0027362832
-
Toxic and protective effects of L-dopa on mesencephalic cell cultures
-
Mytilineou C, Han SK, Cohen G. Toxic and protective effects of L-dopa on mesencephalic cell cultures. J Neurochem 1993; 61:1470-1478
-
(1993)
J Neurochem
, vol.61
, pp. 1470-1478
-
-
Mytilineou, C.1
Han, S.K.2
Cohen, G.3
-
71
-
-
0030059868
-
L-dopa upregulates glutathione and protects mesencephalic cultures against oxidative stress
-
Han SK, Mytilineou C, Cohen G. L-dopa upregulates glutathione and protects mesencephalic cultures against oxidative stress. J Neurochem 1996;66:501-510
-
(1996)
J Neurochem
, vol.66
, pp. 501-510
-
-
Han, S.K.1
Mytilineou, C.2
Cohen, G.3
-
72
-
-
0030010238
-
Levodopa and deprenyl treatment effects on peripheral indices of oxidant stress in Parkinson's disease
-
Ahlskog JE, Uitti RJ, Low PA, Tyce GM, O'Brien JF, Nickander KK. Levodopa and deprenyl treatment effects on peripheral indices of oxidant stress in Parkinson's disease. Neurology 1996;46:796-801
-
(1996)
Neurology
, vol.46
, pp. 796-801
-
-
Ahlskog, J.E.1
Uitti, R.J.2
Low, P.A.3
Tyce, G.M.4
O'Brien, J.F.5
Nickander, K.K.6
-
73
-
-
0020025318
-
Compensatory mechanisms in nigrostriatal dopaminergic system in parkinsonism: Studies in an animal model
-
Melamed E, Hefti F, Wurtman RJ. Compensatory mechanisms in nigrostriatal dopaminergic system in parkinsonism: studies in an animal model. Israel J Med Sci 1982;18:159-163
-
(1982)
Israel J Med Sci
, vol.18
, pp. 159-163
-
-
Melamed, E.1
Hefti, F.2
Wurtman, R.J.3
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