Reversible nephrotoxicity of onconase and effect of lysine pH on renal onconase uptake

Cancer Chemotherapy and Pharmacology

Volumn 44, Issue 2, 1999, Pages 164-169

  Vasandani, Veena M ^a,c   Burris, Jennifer A ^b,d   Sung, Cynthia ^b  

^a National Institute of Neurological Disorders   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

^d Center for Drug Evaluation and Research   (United States)

Author keywords

Lysine; Metabolic acidosis; Nephrotoxicity; pH; Ribonuclease

Indexed keywords

LYSINE; RANPIRNASE; RIBONUCLEASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; HISTOPATHOLOGY; INTRAPERITONEAL DRUG ADMINISTRATION; KIDNEY TUBULE ABSORPTION; KIDNEY TUBULE NECROSIS; METABOLIC ACIDOSIS; MOUSE; NEPHROTOXICITY; NONHUMAN; PH; PRIORITY JOURNAL;

ACIDOSIS; ANIMALS; ANTINEOPLASTIC AGENTS; EGG PROTEINS; FEMALE; HYDROGEN-ION CONCENTRATION; KIDNEY; LYSINE; MICE; MICE, INBRED BALB C; RIBONUCLEASES;

EID: 0033051964     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002800050962     Document Type: Article

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