Role of the N terminus in RNase a homologues: Differences in catalytic activity, ribonuclease inhibitor interaction and cytotoxicity

Journal of Molecular Biology

Volumn 257, Issue 5, 1996, Pages 992-1007

  Boix, Ester ^a   Wu, YouNeng ^a   Vasandani, Veena M ^a   Saxena, Shailendra K ^a   Ardelt, Wojciech ^b   Ladner, Jane ^c   Youle, Richard J ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b Alfacell Corporation   (United States)

^c UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

Author keywords

Cytotoxicity; Human pancreatic RNase; Pyroglutamic acid; Rana pipiens RNase; Ribonuclease inhibitor

Indexed keywords

ENZYME INHIBITOR; METHIONINE; RIBONUCLEASE A;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CATALYSIS; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME SUBSTRATE; ESCHERICHIA COLI; EXPRESSION VECTOR; FROG; NONHUMAN; PRIORITY JOURNAL; SEQUENCE HOMOLOGY;

AMPHIBIA; ANIMALIA; ANURA; ESCHERICHIA COLI; RANA PIPIENS;

EID: 0029871341     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1996.0218     Document Type: Article

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