Human pancreatic RNase1-human epidermal growth factor fusion: An entirely human 'immunotoxin analog' with cytotoxic properties against squamous cell carcinomas

Protein Engineering

Volumn 11, Issue 12, 1998, Pages 1285-1292

  Psarras, Kyriakos ^a   Ueda, Masakazu ^a   Yamamura, Tadashi ^a   Ozawa, Soji ^a   Kitajima, Masaki ^a   Aiso, Sadakazu ^a   Komatsu, Setsuko ^b   Seno, Masaharu ^c  

^a KEIO UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF AGROBIOLOGICAL SCIENCES   (Japan)

^c OKAYAMA UNIVERSITY   (Japan)

Author keywords

EGF receptor; Fusion protein; Human pancreatic RNase1; Immunotoxin analog; Targeted therapy

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; GAMMA UROGASTRONE; HYBRID PROTEIN; IMMUNOTOXIN; IODINE 125; PANCREATIC RIBONUCLEASE;

ARTICLE; BREAST CANCER; CELL INCLUSION; CELL LINE; CONTROLLED STUDY; CYTOTOXICITY; DRUG TARGETING; ENZYME ACTIVITY; ESCHERICHIA COLI; ESOPHAGUS CANCER; GENE FUSION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNOGENICITY; LUNG CANCER; NONHUMAN; PRIORITY JOURNAL; PROGNOSIS; PROTEIN PURIFICATION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SQUAMOUS CELL CARCINOMA;

EID: 0032423372     PISSN: 02692139     EISSN: None     Source Type: Journal    
DOI: 10.1093/protein/11.12.1285     Document Type: Article

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