Reactive oxygen species mediate pyridostigmine-induced neuronal apoptosis: Involvement of muscarinic and NMDA receptors

Toxicology and Applied Pharmacology

Volumn 177, Issue 1, 2001, Pages 17-25

  Li, Li ^a   Shou, Yan ^a   Borowitz, Joseph L ^a   Isom, Gary E ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

Apoptosis; Atropine; Catalase; L NAME; MK 801; Pyridostigmine; Reactive oxygen species; Superoxide dismutase

Indexed keywords

ANTIOXIDANT; ATROPINE; CASPASE; CATALASE; CYTOCHROME C; DICHLORODIHYDROFLUORESCEIN DIACETATE; DIZOCILPINE; DNA; DNA FRAGMENT; LACTATE DEHYDROGENASE; MUSCARINIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N TERT BUTYL ALPHA PHENYLNITRONE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE INHIBITOR; OXIDIZING AGENT; PYRIDOSTIGMINE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN CELL; CELL CULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; ELECTRON MICROSCOPY; ENZYME ACTIVITY; ENZYME RELEASE; GEL ELECTROPHORESIS; GRANULE CELL; INCUBATION TIME; MITOCHONDRION; NEUROTOXICITY; NICK END LABELING; NONHUMAN; RAT;

EID: 0035891558     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.2001.9283     Document Type: Article

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