Relatively normal human lymphopoiesis but rapid turnover of newly formed B cells in transplanted nonobese diabetic/SCID mice

Journal of Immunology

Volumn 167, Issue 6, 2001, Pages 3033-3042

  Rossi, M I D ^a   Medina, K L ^a   Garrett, K ^a   Kolar, G ^a   Comp, P C ^a   Shultz, L D ^a   Capra, J D ^a   Wilson, P ^a   Schipul, A ^a   Kincade, P W ^a  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BROXURIDINE; CD5 ANTIGEN; KI 67 ANTIGEN;

ADULT; AGED; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; BLOOD CELL; CELL CYCLE; CELL TRANSPLANTATION; CHIMERA; GENE REARRANGEMENT; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOGLOBULIN GENE; LYMPHOCYTOPOIESIS; LYMPHOPOIESIS; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; SCID MOUSE; UMBILICAL CORD BLOOD;

EID: 0035885120     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.167.6.3033     Document Type: Article

References (77)

1. Inhibition of murine B and T lymphopoiesis in vivo by an anti-interleukin 7 monoclonal antibody
2. The growth response to IL-7 during normal human B cell ontogeny is restricted to B-lineage cells expressing CD34
3. Interleukin 7 independent development of human B cells
4. Role of the common cytokine receptor gamma chain in cytokine signaling and lymphoid development
5. Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agamma-globulinemia
6. Genetic basis of abnormal B cell development
7. Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: Implications for gene therapy
8. Phenotype and function of human hematopoietic cells engrafting immune-deficient CB17-severe combined immunodeficiency mice and nonobese diabetic-severe combined immunodeficiency mice after transplantation of human cord blood mononuclear cells
9. SCID mouse models of human stem cell engraftment
10. Purification of primitive human hematopoietic cells capable of repopulating immune-deficient mice
11. +-enriched cells from umbilical cord blood in NOD/LtSz-scid/scid mice
12. + B lymphoid cells in NOD/SCID mice
13. Dynamic changes in mouse hematopoietic stem cell numbers during aging
14. H gene families
15. Ontogeny of the heavy chain immunoglobulin repertoire in fetal liver and bone marrow
16. IgM heavy chain complementarity-determining region 3 diversity is constrained by genetic and somatic mechanisms until two months after birth
17. CD5 B cells, a fetal B cell lineage
18. + B cells
19. B cell antigen receptor specificity and surface density together determine B-1 versus B-2 cell development
20. + B cells both in vivo and in vitro
21. Accumulation of bromodeoxyuridine-labeled cells in central and peripheral lymphoid organs: Minimal estimates of production and turnover rates of mature lymphocytes
22. - B cells: Requirement for special stimuli
23. high splenic B cells are an immature developmental intermediate in the production of long-lived marrow-derived B cells
24. Analysis of the heavy chain repertoire of human peripheral B cells using single-cell polymerase chain reaction
25. Full reconstitution of the immune deficiency in scid mice with normal stem cells requires low-dose irradiation of the recipients
26. Kinetic evidence of the regeneration of multilineage hematopoiesis from primitive cells in normal human bone marrow transplanted into immunodeficient mice
27. Treatment of non-obese diabetic (NOD)/severe-combined immunodeficient mice (SCID) with flt3 ligand and interleukin-7 impairs the B-lineage commitment of repopulating cells after transplantation of human hematopoietic cells
28. Human T, B, natural killer, and dendritic cells arise from a common bone marrow progenitor cell subset
29. Four-color flow cytometric investigation of terminal deoxynucleotidyl transferase-positive lymphoid precursors in pediatric bone marrow: CD79a expression precedes CD19 in early B-cell ontogeny
30. Normal human bone marrow precursors that express terminal deoxynucleotidyl transferase include T-cell precursors and possible lymphoid stem cells
31. B cells are generated throughout life in humans
32. B cell maintenance in aged mice reflects both increased B cell longevity and decreased B cell generation
33. Lymphocyte population kinetics in the mouse
34. B cell life span: A review
35. Regulation of pre-B cell proliferation in bone marrow: Immunofluorescent stathmokinetic studies of cytoplasmic L-chain bearing cells in anti-IgM treated, hematologically deficient mutant and antigen stimulated mice
36. High-resolution cell cycle analysis of defined phenotypic subsets within primitive human hematopoietic cell populations
37. - cells in cord blood and bone marrow
38. B cell development in the bone marrow
39. H4.21 expression in the normal human B-cell repertoire
40. Analysis of Ig H chain gene segment utilization in human fetal liver: Revisiting the "proximal utilization hypothesis"
41. H7 gene family
42. Human cord blood antibody repertoire. Mixed population of VH gene segments and CDR3 distribution in the expressed Cα and Cγ repertoires
43. The diversity of rearranged immunoglobulin heavy chain variable region genes in peripheral blood B cells of preterm infants is restricted by short third complementarity-determining regions but not by limited gene segment usage
44. Current status of umbilical cord blood hematopoietic stem cell transplantation
45. - cells
46. Immature human cord blood progenitors engraft and proliferate to high levels in severe combined immunodeficient mice
47. Functional differences between transplantable human hematopoietic stem cells from fetal liver, cord blood, and adult marrow
48. 2- microglobulin-null mice
49. o
50. + cells in NOD/SCID mice
51. Sustained proliferation, multi-lineage differentiation and maintenance of primitive human haemopoietic cells in NOD/SCID mice transplanted with human cord blood
52. Release from quiescence of primitive human hematopoietic stem/progenitor cells by blocking their cell-surface TGF-β type II receptor in a short-term in vitro assay
53. Differentiation stage-specific regulation of primitive human hematopoietic progenitor cycling by exogenous and endogenous inhibitors in an in vivo model
54. Stepwise specification of lymphocyte developmental lineages
55. Fidelity and infidelity in commitment to B-lymphocyte lineage development
56. Multiparameter flow cytometric analysis of human fetal bone marrow B cells
57. IgD (H) gene segment transcription and rearrangement before surface expression of the pan-B-cell marker CD19 in normal human bone marrow
58. + cells
59. Dynamics of early B lymphocyte precursor cells in mouse bone marrow: Proliferation of cells containing terminal deoxynucleotidyl transferase
60. Idiotypic cross-reactions of monoclonal human lupus autoantibodies
61. + B) cells
62. The CD5 B cell
63. Phenotype of recovering lymphoid cell populations after marrow transplantation
64. B lymphocyte reconstitution after human bone marrow transplantation. Leu-I antigen defines a distinct population of B lymphocytes
65. Nucleotide sequence analysis of the V regions of two IgM cold agglutinins: Evidence that the VH4-21 gene segment is responsible for the major cross-reactive idiotype
66. H4-21 gene segment is required to encode anti-I and anti-i specificities
67. H4-21 gene segment
68. Human antilipid A monoclonal antibodies bind to human B cells and the I antigen on cord red blood cells
69. An anti-B cell autoantibody from Wiskott-Aldrich syndrome which recognizes I blood group specificity on normal human B cells
70. H4-21 variable region gene-associated epitope
71. Characterization of immature B cells by a novel monoclonal antibody, by turnover and by mitogen reactivity
72. Kinetics of B-cell subpopulations in peripheral lymphoid tissues - Evidence for the presence of phenotypically distinct short-lived and long-lived B-cell subsets
73. In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death
74. Rapid elimination of mature autoreactive B cells demonstrated by Cre-induced change in B cell antigen receptor specificity in vivo
75. BLC expression in pancreatic islets causes B cell recruitment and lymphotoxin-dependent lymphoid neogenesis
76. Early arrest of B cell development in nude, X-linked immune-deficient mice
77. Follicular exclusion and rapid elimination of hen egg lysozyme autoantigen-binding B cells are dependent on competitor B cells, but not on T cells