Development of Epstein-Barr virus-specific memory T cell receptor clonotypes in acute infectious mononucleosis

Journal of Experimental Medicine

Volumn 184, Issue 5, 1996, Pages 1815-1824

  Silins, Sharon L ^a   Cross, Simone M ^a   Elliott, Suzanne L ^a   Pye, Stephanie J ^a   Burrows, Scott R ^a   Burrows, Jacqueline M ^a   Moss, Denis J ^a   Argaet, Victor P ^a   Misko, Ihor S ^a  

^a QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; EPITOPE; HLA B8 ANTIGEN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M; MESSENGER RNA; T LYMPHOCYTE RECEPTOR; VIRUS ANTIGEN;

ARTICLE; CASE REPORT; CLONE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; EPSTEIN BARR VIRUS; GENE EXPRESSION; HUMAN; HUMAN CELL; INFECTIOUS MONONUCLEOSIS; MEMORY CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

EID: 0029826203     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.184.5.1815     Document Type: Article

References (51)

1. Henle, W., V. Diehl, G. Kohn, H. zur Hausen, and G. Henle. 1967. Herpes-type virus and chromosome marker in normal leukocytes after growth with irradiated Burkitt cells. Science (Wash. DC). 169:188-190.
2. Pope, J.H., M.K. Horne, and W. Scott. 1968. Transformation of fetal human leukocytes in vitro by filtrates of a human leukemic cell line containing herpes-like virus. Int. J. Cancer. 3:844-857.
3. Moss, D.J., S.R. Burrows, R. Khanna, I.S. Misko, and T.B. Sculley. 1992. Immune surveillance against Epstein-Barr virus. Sem. Immunol. 4:97-104.
4. Henle, G., and W. Henle. 1979. The virus as the etiological agent of infectious mononucleosis. In The Epstein-Barr Virus. M.A. Epstein and B.G. Achong, editors. Springer-Verlag, Berlin. 297-320.
5. Tomkinson, B.E., D.K. Wagner, D.L. Nelson, and J.L. Sullivan. 1987. Activated lymphocytes during acute Epstein-Barr virus infection. J. Immunol. 139:3802-3807.
6. Tomkinson, B.E., R. Maziarz, and J.L. Sullivan. 1989. Characterization of the T-cell-mediated cellular cytotoxicity during acute infectious mononucleosis. J. Immunol. 143:660-670.
7. Strang, G., and A.B. Rickinson. 1987. Multiple HLA class I-dependent cytotoxicities constitute the "non-HLA-restricted" response in infectious mononucleosis. Eur. J. Immunol. 17: 1007-1013.
8. Smith, T.J., N. Terada, C.C. Robinson, and E.W. Gelfand. 1993. Acute infectious mononucleosis stimulates the selective expression/expansion of V beta 6.1-3 and V beta 7 T-cells. Blood. 81:1521-1526.
9. Pichler, W.J., D. Mauri Hellweg, K. Baumann, and F. Bettens. 1995. Selective expression of T-cell receptor-V beta in acute infectious mononucleosis. Arch. Intern. Med. 155: 1555-1556.
10. + subsets during acute infectious mononucleosis. Viral Immunol. 7:151-153.
11. Prosser, H.M., and S. Tonegawa. 1995. T cell receptor V(D)J recombination: mechanisms and developmental regulation. In T Cell Receptors. J.I. Bell, M.J. Owen, and E. Simpson, editors. Oxford University Press, New York. 326-352.
12. Davis, M.M., and P.J. Bjorkman. 1988. T-cell antigen receptor genes and T-cell recognition. Nature (Lond.). 334:395-402.
13. Bowness, P., P.A.H. Moss, S. Rowland-Jones, J.I. Bell, and A.J. McMichael. 1993. Conservation of TCR usage by HLA B27-restricted influenza-specific cytotoxic T lymphocytes suggests a general pattern for antigen-specific MHC class I-restricted responses. Eur. J. Immunol. 23:1417-1421.
14. McHeyzer Williams, M.G., and M.M. Davis. 1995. Antigen-specific development of primary and memory T cells in vivo. Science (Wash. DC). 268:106-111.
15. Kalams, S.A., R.P. Johnson, A.K. Trocha, M.J. Dynan, H.S. Ngo, R.T. D'Aquila, J.T. Kurnick, and B.D. Walker. 1994. Longitudinal analysis of T cell receptor (TCR) gene usage by human immunodeficiency virus 1 envelope-specific cytotoxic T lymphocyte clones reveals a limited TCR repertoire. J. Exp. Med. 179:1261-1271.
16. Maryanski, J.L., C.V. Jongeneet, P. Bucher, J. Casanova, and P.R. Walker. 1996. Single-cell PCR analysis of TCR repertoires selected by antigen in vivo: a high magnitude CD8 response is comprised of very few clones. Immunity. 4:47-55.
17. Argaet, V.P., C.W. Schmidt, S.R. Burrows, S.L. Silins, M.G. Kurilla, D.L. Doolan, A. Suhrbier, D.J. Moss, E. Kieff, T.B. Sculley, and I.S. Misko. 1994. Dominant selection of an invariant T-cell antigen receptor in response to persistent infection by Epstein-Barr virus. J. Exp. Med. 180:2335-2340.
18. Silins, S.L., S.R. Burrows, D.J. Moss, R. Khanna, I.S. Misko, and V.P. Argaet. 1995. T cell receptor repertoire for a viral epitope in humans is diversified by tolerance to a background major histocompatibility complex antigen. J. Exp. Med. 182: 1-13.
19. Burrows, S.R., R. Khanna, J.M. Burrows, and D.J. Moss. 1994. An alloresponse in humans is dominated by cytotoxic T lymphocytes (CTL) cross-reactive with a single Epstein-Barr virus CTL epitope: implications for graft-versus-host disease. J. Exp. Med. 179:1155-1161.
20. Burrows, J.M., R. Khanna, T.B. Sculley, M.P. Alpers, D.J. Moss, and S.R. Burrows. 1996. Identification of a naturally occurring recombinant Epstein-Barr virus isolate from New Guinea that encodes both type 1 and type 2 nuclear antigen sequences. J. Virol. 70:4829-4833.
21. Moss, D.J., I.S. Misko, S.R. Burrows, K. Burman, R. McCarthy, and T.B. Sculley. 1988. Cytotoxic T-cell clones discriminate between A- and B-type Epstein-Barr virus transformants. Nature (Lond.). 331:719-721.
22. Burrows, S.R., T.B. Sculley, I.S. Misko, C. Schmidt, and D.J. Moss. 1990. An Epstein-Barr virus-specific cytotoxic T-cell epitope in EBV nuclear antigen 3 (EBNA 3). J. Exp. Med. 171:345-349.
23. Wang, A., S.D. Lu, and D.F. Mark. 1984. Site-specific mutagenesis of the human interleukin-2 gene: structure-function analysis of the cysteine residues. Science (Wash. DC). 224: 1431-1433.
24. Rosenberg, S.A., E.A. Grimm, M. McGrogan, M. Doyle, E. Kawasaki, K. Koths, and D.F. Mark. 1984. Biological activity of recombinant human interleukin-2 produced in Escherichia coli. Science (Wash. DC). 223:1412-1414.
25. Burrows, S.R., J. Gardner, R. Khanna, T. Steward, D.J. Moss, S. Rodda, and A. Suhrbier. 1994. Five new cytotoxic T cell epitopes identified within Epstein-Barr virus nuclear antigen 3. J. Gen. Virol. 75:2489-2493.
26. Misko, I.S., J.H. Pope, R. Hutter, T.D. Soszynski, and R.G. Kane. 1984. HLA-DR-antigen-associated restriction of EBV-specific cytotoxic T-cell colonies. Int. J. Cancer 33:239-243.
27. Bishop, C.J., D.J. Moss, J.M. Ryan, and S.R. Burrows. 1985. T lymphocytes in infectious mononucleosis. II. Response in vitro to interleukin-2 and establishment of T-cell lines. Clin. Exp. Immunol. 60:70-77.
28. Burrows, S.R., A. Suhrbier, R. Khanna, and D.J. Moss. 1992. Rapid visual assay of cytotoxic T-cell specificity utilizing synthetic peptide induced T-cell-T-cell killing. Immunology. 76:174-175.
29. Panzara, M.A., E. Gussoni, L. Steinman, and J.R. Oksenberg. 1992. Analysis of the T cell repertoire using the PCR and specific oligonucleotide primers. Biotechniques. 12:728-735.
30. Tan, S.S., and J.H. Weis. 1992. Development of a sensitive reverse transcriptase PCR assay, RT-RPCR, utilizing rapid cycle times. PCR. Methods Appl. 2:137-143.
31. Arden, B., S.P. Clark, D. Kabelitz, and T.W. Mak. 1995. Human T-cell receptor variable gene segment families. Immunogenetics. 42:455-500.
32. Toyonaga, B., Y. Yoshikai, V. Vadasz, B. Chin, and T.W. Mak. 1985. Organization and sequences of the diversity, joining, and constant region genes of the human T-cell receptor beta chain. Proc. Natl. Acad. Sci. USA. 82:8624-8628.
33. Chothia, C., D.R. Boswell, and A.M. Lesk. 1988. The outline structure of the T-cell alpha beta receptor. EMBO (Eur. Mol. Biol. Organ.) J. 7:3745-3755.
34. Malissen, M., J. Trucy, F. Letourneur, N. Rebai, D.E. Dunn, F.W. Fitch, L. Hood, and B. Malissen. 1988. A T-cell clone expresses two T-cell receptor alpha genes but uses one alpha beta heterodimer for allorecognition and self MHC-restricted antigen recognition. Cell. 55:49-59.
35. Jorgensen, J.L., U. Esser, B. Fazekas de St. Groth, P.A. Reay, and M.M. Davis. 1992. Mapping TCR-peptide contacts by variant peptide immunization of single-chain transgenics. Nature (Lond.). 355:224-230.
36. Strang, G., and A.B. Rickinson. 1987. In vitro expansion of Epstein-Barr virus-specific HLA-restricted cytotoxic T-cells direct from the blood of infectious mononucleosis. Immunology. 62:647-654.
37. Sercarz, E.E., P.V. Lehmann, A. Ametani, G. Benichou, A. Miller, and K. Moudgil. 1993. Dominance and crypticity of T-cell antigenic determinants. Annu. Rev. Immunol. 11:729-766.
38. Katsuki, T., Y. Hinuma, T. Saito, J. Yamamoto, Y. Hirashima, H. Sudoh, M. Deguchi, and M. Motokawa. 1979. Simultaneous presence of EBNA-positive and colony-forming cells in peripheral blood of patients with infectious mononucleosis. Int. J. Cancer. 23:746-750.
39. Klein, G., E. Svedmyr, M. Jondal, and P.O. Persson. 1976. EBV-determined nuclear antigen (EBNA)-positive cells in the peripheral blood of infectious mononucleosis patients. Int. J. Cancer. 17:21-26.
40. Tierney, R.J., N. Steven, L.S. Young, and A.B. Rickinson. 1994. Epstein-Barr virus latency in blood mononuclear cells: analysis of viral gene transcription during primary infection and in the carrier. J. Virol. 68:7374-7385.
41. Bourgault, I., A. Gomez, E. Gomard, and J.P. Levy. 1991. Limiting-dilution analysis of the HLA restriction of anti-Epstein-Barr virus-specific cytotoxic T lymphocytes. Clin. Exp. Immunol. 84:501-507.
42. Cose, S.C., J.M. Kelly, and F.R. Carbone. 1995. Characterization of diverse primary herpes simplex virus type 1 gB-specific cytotoxic T-cell response showing a preferential V beta bias. J. Virol. 69:5849-5852.
43. + cytotoxic T lymphocytes from patients with HTLV-1-associated disease: evidence for oligoclonal expansion. J. Virol. 70:843-851.
44. + T-cells with a predominant V beta usage during the primary immune response to HIV. Nature (Lond.). 370:463-467.
45. Moskophidis, D., F. Lechner, H. Pircher, and R.M. Zinkernagel. 1993. Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells. Nature (Lond.). 362:758-761.
46. Chen, Z.W., Z.C. Kou, C. Lekutis, L. Shen, D. Zhou, M. Halloran, J. Li, J. Sodroski, D. Lee Parritz, and N.L. Letvin. 1995. T cell receptor V beta repertoire in an acute infection of rhesus monkeys with simian immunodeficiency viruses and a chimeric simian-human immunodeficiency virus. J. Exp. Med. 182:21-31.
47. Posnett, D.M., R. Sinha, S. Kabak, and C. Russo. 1994. Clonal populations of T cells in normal elderly humans: the T cell equivalent to "benign monoclonal gammapathy." J. Exp. Med. 179:609-618.
48. + subset in normal human subjects. J. Immunol. 151:5762-5769.
49. 8+ T-cell memory to viruses. Curr. Opin. Immunol. 6:545-552.
50. 11+ population. Science (Wash. DC). 260:98-100.
51. Burrows, J.M., S.R. Burrows, L.M. Poulsen, T.B. Sculley, D.J. Moss, and R. Khanna. 1996. Unusually high frequency of Epstein-Barr virus genetic variants in Papua New Guinea that can escape cytotoxic T-cell recognition: implications for virus evolution. J. Virol. 70:2490-2496.