Double-stranded RNA-dependent protein kinase, PKR, binds preferentially to Huntington's diseases (HD) transcripts and is activated in HD tissue

Human Molecular Genetics

Volumn 10, Issue 15, 2001, Pages 1531-1538

  Peel, Alyson L ^a   Rao, Ram V ^a   Cottrell, Barbara A ^a   Hayden, Michael R ^b   Ellerby, Lisa M ^a   Bredesen, Dale E ^a  

^a BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; BRAIN EXTRACT; CYTOSINE; DOUBLE STRANDED RNA; GUANINE; HUNTINGTIN; NUCLEOTIDE; POLYGLUTAMINE; PROTEIN KINASE; RNA; RNA BINDING PROTEIN; STREPTAVIDIN; TYROSINE;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPSY; BRAIN TISSUE; DISEASE COURSE; ENZYME ACTIVATION; GENE ACTIVATION; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN TISSUE; HUNTINGTON CHOREA; IMMUNOHISTOCHEMISTRY; INCUBATION TIME; MODEL; MOUSE; NEUROLOGIC DISEASE; NONHUMAN; PATHOLOGY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN IMMOBILIZATION; RNA BINDING; RNA TRANSCRIPTION; RNA TRANSLATION; STRESS; TISSUE SLICE; TRANSGENIC MOUSE; TRINUCLEOTIDE REPEAT; YEAST ARTIFICIAL CHROMOSOME;

ANIMALS; BIOTINYLATION; BLOTTING, WESTERN; BRAIN; CHROMOSOMES, ARTIFICIAL, YEAST; CYTOPLASM; EIF-2 KINASE; HUMANS; HUNTINGTON DISEASE; IMMUNOHISTOCHEMISTRY; MICE; MICE, TRANSGENIC; MUTATION; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEIN BINDING; RNA; STREPTAVIDIN;

ANIMALIA; MUS MUSCULUS;

EID: 0035878553     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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