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Volumn 82, Issue 1, 1996, Pages 76-85

The mevalonate pathway in parasitic protozoa and helminths

Author keywords

[No Author keywords available]

Indexed keywords

ANTIPARASITIC AGENT; KETOCONAZOLE; MEFLOQUINE; MEVALONIC ACID; MEVINOLIN; MICONAZOLE; PYRROLE; SIMVASTATIN; TERBINAFINE; TUNICAMYCIN;

EID: 0029865434     PISSN: 00144894     EISSN: None     Source Type: Journal    
DOI: 10.1006/expr.1996.0011     Document Type: Article
Times cited : (21)

References (60)
  • 1
    • 0015840324 scopus 로고
    • Helminths: Comparison of their rhodoquinone
    • ALLEN, P. C. 1973. Helminths: Comparison of their rhodoquinone. Experimental Parasitology 34, 211-219.
    • (1973) Experimental Parasitology , vol.34 , pp. 211-219
    • Allen, P.C.1
  • 2
    • 0023779728 scopus 로고
    • Structural and functional conservation between yeast and human 3-hydroxy-3-methylglutaryl coenzyme A reductases, the rate-limiting enzyme of sterol biosynthesis
    • BASSON, M. E., THORSNESS, M., FINER-MOORE, J., STROUD, R. M., AND RINE, J. 1988. Structural and functional conservation between yeast and human 3-hydroxy-3-methylglutaryl coenzyme A reductases, the rate-limiting enzyme of sterol biosynthesis. Molecular and Cellular Biology 8, 3797-3808.
    • (1988) Molecular and Cellular Biology , vol.8 , pp. 3797-3808
    • Basson, M.E.1    Thorsness, M.2    Finer-Moore, J.3    Stroud, R.M.4    Rine, J.5
  • 3
    • 0019064311 scopus 로고
    • Benzoquinones in stages of the life-cycle of the cestode, spirometra mansonoides
    • BEACH, D. H., MUELLER, J. F., AND HOLZ, G. G. 1980. Benzoquinones in stages of the life-cycle of the cestode, Spirometra mansonoides. Molecular and Biochemical Parasitology 1, 269-278.
    • (1980) Molecular and Biochemical Parasitology , vol.1 , pp. 269-278
    • Beach, D.H.1    Mueller, J.F.2    Holz, G.G.3
  • 4
    • 0022497077 scopus 로고
    • Effects of ketoconazole on sterol biosynthesis by Trypanosoma cruzi epimastigotes
    • BEACH, D. H., GOAD, L. J., AND HOLZ, G. G. 1986. Effects of ketoconazole on sterol biosynthesis by Trypanosoma cruzi epimastigotes. Biochemical Biophysical Research Communication 136, 851-856.
    • (1986) Biochemical Biophysical Research Communication , vol.136 , pp. 851-856
    • Beach, D.H.1    Goad, L.J.2    Holz, G.G.3
  • 5
    • 0021233074 scopus 로고
    • Effects of ketoconazole on growth and sterol biosynthesis of Leishmania mexicana promastigotes in culture
    • BERMAN, J. D., HOLZ, G. G., AND BEACH, D. H. 1984. Effects of ketoconazole on growth and sterol biosynthesis of Leishmania mexicana promastigotes in culture. Molecular and Biochemical Parasitology 12, 1-13.
    • (1984) Molecular and Biochemical Parasitology , vol.12 , pp. 1-13
    • Berman, J.D.1    Holz, G.G.2    Beach, D.H.3
  • 6
    • 0024869502 scopus 로고
    • Isolation and structural charac-terization of a cDNA encoding Arabidopsis thaliana 3-hydroxy-3-methylglutaryl coenzyme A reductase
    • CAELLES, C., FERRER, A., BALCELLS, L., HEGARDT, F. G., AND BORONAT, A. 1989. Isolation and structural charac-terization of a cDNA encoding Arabidopsis thaliana 3-hydroxy-3-methylglutaryl coenzyme A reductase. Plant Molecular Biology 13, 627-638.
    • (1989) Plant Molecular Biology , vol.13 , pp. 627-638
    • Caelles, C.1    Ferrer, A.2    Balcells, L.3    Hegardt, F.G.4    Boronat, A.5
  • 7
    • 0025255477 scopus 로고
    • Nucleotide sequence and estrogen induction of Xenopus laevis 3-hydroxy-3-methylglutaryl coenzyme A reductase
    • CHEN, H., AND SHAPIRO, D. J. 1990. Nucleotide sequence and estrogen induction of Xenopus laevis 3-hydroxy-3-methylglutaryl coenzyme A reductase. The Journal of Biological Chemistry 265, 4622-4629.
    • (1990) The Journal of Biological Chemistry , vol.265 , pp. 4622-4629
    • Chen, H.1    Shapiro, D.J.2
  • 8
    • 0026196266 scopus 로고
    • Purification and characterization of 3-hydroxymethylglutaryl coenzyme A reductase of Schistosoma mansoni: Regulation of parasite enzyme activity differs from mammalian host
    • CHEN, G.-Z., FOSTER, L., AND BENNETT, J. L. 1991. Purification and characterization of 3-hydroxymethylglutaryl coenzyme A reductase of Schistosoma mansoni: Regulation of parasite enzyme activity differs from mammalian host. Experimental Parasitology 73, 82-92.
    • (1991) Experimental Parasitology , vol.73 , pp. 82-92
    • Chen, G.-Z.1    Foster, L.2    Bennett, J.L.3
  • 9
    • 0027154011 scopus 로고
    • Characterization of mevalonate-labeled lipids isolated from parasite proteins in Schistosoma mansoni
    • CHEN, G.-Z., AND BENNETT, J. L. 1993. Characterization of mevalonate-labeled lipids isolated from parasite proteins in Schistosoma mansoni. Molecular and Biochemical Parasitology 59, 287-292.
    • (1993) Molecular and Biochemical Parasitology , vol.59 , pp. 287-292
    • Chen, G.-Z.1    Bennett, J.L.2
  • 11
    • 0022295568 scopus 로고
    • Sterols of Echinostoma revolutum (Trematoda) adults
    • CHITWOOD, D. J., LUSBY, W. R., AND FRIED, B. 1985. Sterols of Echinostoma revolutum (Trematoda) adults. Journal of Parasitology 71, 846-847.
    • (1985) Journal of Parasitology , vol.71 , pp. 846-847
    • Chitwood, D.J.1    Lusby, W.R.2    Fried, B.3
  • 12
    • 0026742974 scopus 로고
    • The role of the membrane domain in the regulated degradation of 3-hydroxy-3-methylglutaryl coenzyme A reductase
    • CHUN, K. T., AND SIMONI, R. D. 1992. The role of the membrane domain in the regulated degradation of 3-hydroxy-3-methylglutaryl Coenzyme A reductase. The Journal of Biological Chemistry 267, 4236-4246.
    • (1992) The Journal of Biological Chemistry , vol.267 , pp. 4236-4246
    • Chun, K.T.1    Simoni, R.D.2
  • 13
    • 0007372508 scopus 로고
    • Hydroxymethylglutaryl-CoA reductase in Trypanosoma brucei: Activity, pharmacological inhibition and biological regulation
    • COPPENS, I., BASTIN, PH., LEVADE, T., AND COURTOY, P.-J. 1995. Hydroxymethylglutaryl-CoA reductase in Trypanosoma brucei: Activity, pharmacological inhibition and biological regulation. Molecular and Biochemical Parasitology 69, 28-40.
    • (1995) Molecular and Biochemical Parasitology , vol.69 , pp. 28-40
    • Coppens, I.1    Bastin, P.H.2    Levade, T.3    Courtoy, P.-J.4
  • 14
    • 0019875779 scopus 로고
    • Effect on sterol structure on acyl chain ordering in phosphatidylcholine vesicles: A deuterium nuclear magnetic resonance and electron spin resonance study
    • DALH, C. 1981. Effect on sterol structure on acyl chain ordering in phosphatidylcholine vesicles: A deuterium nuclear magnetic resonance and electron spin resonance study. Biochemistry 20, 7158-7161.
    • (1981) Biochemistry , vol.20 , pp. 7158-7161
    • Dalh, C.1
  • 18
    • 0028101772 scopus 로고
    • Coenzyme Q homologs in parasitic protozoa as targets for chemotherapeutic attack
    • ELLIS, J. E. 1994. Coenzyme Q homologs in parasitic protozoa as targets for chemotherapeutic attack. Parasitology Today 10, 296-301.
    • (1994) Parasitology Today , vol.10 , pp. 296-301
    • Ellis, J.E.1
  • 19
    • 0017399524 scopus 로고
    • The identification and characterization of a prenoid constituent (farnesol) of Hymenolepis diminuta (cestoda)
    • FIORAVANTI, C. F., AND MACINNIS, A. J. 1987. The identification and characterization of a prenoid constituent (farnesol) of Hymenolepis diminuta (Cestoda). Comparative Biochemistry and Physiology 57B, 227-233.
    • (1987) Comparative Biochemistry and Physiology , vol.57 B , pp. 227-233
    • Fioravanti, C.F.1    Macinnis, A.J.2
  • 22
    • 0020992895 scopus 로고
    • Lipid metabolism in parasitic helminths
    • FRAYHA, G. J., AND SMYTH, J. D. 1983. Lipid metabolism in parasitic helminths. Advances in Parasitology 22, 309-387.
    • (1983) Advances in Parasitology , vol.22 , pp. 309-387
    • Frayha, G.J.1    Smyth, J.D.2
  • 23
    • 0024672966 scopus 로고
    • Sterols of parasitic protozoa and helminths
    • FURLONG, S. T. 1989. Sterols of parasitic protozoa and helminths. Experimental Parasitology 68, 482-485.
    • (1989) Experimental Parasitology , vol.68 , pp. 482-485
    • Furlong, S.T.1
  • 24
    • 0023919601 scopus 로고
    • Schistosoma mansoni: Sterol and phospholipid composition of cercariae, schistosomula, and adults
    • FURLONG, S. T., AND CAULFIELD, J. P. 1988. Schistosoma mansoni: Sterol and phospholipid composition of cercariae, schistosomula, and adults. Experimental Parasitology 65, 222-231.
    • (1988) Experimental Parasitology , vol.65 , pp. 222-231
    • Furlong, S.T.1    Caulfield, J.P.2
  • 25
    • 0022536417 scopus 로고
    • HMG-CoA reductase activity in digitonin - The rate-limiting enzyme of cholesterol biosynthesis
    • GEELEN, M. J. H., GIBSON, D. M., AND RODWELL, V. W. 1986. HMG-CoA reductase activity in digitonin - The rate-limiting enzyme of cholesterol biosynthesis. FEBS Letters 10, 183-186.
    • (1986) FEBS Letters , vol.10 , pp. 183-186
    • Geelen, M.J.H.1    Gibson, D.M.2    Rodwell, V.W.3
  • 26
    • 0024039673 scopus 로고
    • Developmental and metabolic regulation of the Drosophila melanogaster 3-hydroxy-3-methylglutaryl coenzyme A reductase
    • GERTLER, F. B., CHIU, C.-Y., RICHTER-MANN, L., AND CHIN, D. J. 1988. Developmental and metabolic regulation of the Drosophila melanogaster 3-hydroxy-3-methylglutaryl coenzyme A reductase. Molecular and Cellular Biology 8, 2713-2721.
    • (1988) Molecular and Cellular Biology , vol.8 , pp. 2713-2721
    • Gertler, F.B.1    Chiu, C.-Y.2    Richter-Mann, L.3    Chin, D.J.4
  • 28
    • 0025120211 scopus 로고
    • Regulation of the mevalonate pathway
    • GOLDSTEIN, J. L., AND BROWN, M. S. 1990. Regulation of the mevalonate pathway. Nature 343, 425-430.
    • (1990) Nature , vol.343 , pp. 425-430
    • Goldstein, J.L.1    Brown, M.S.2
  • 29
    • 0028217652 scopus 로고
    • 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors lovastatin and simvastatin inhibit in vitro development of Plasmodium falciparum and Babesia divergens in human erythrocytes
    • GRELLIER, P., VALENTIN, A., MILLEROUX, V., SCHREVEL, J., AND RIGOMIER, D. 1994. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors lovastatin and simvastatin inhibit in vitro development of Plasmodium falciparum and Babesia divergens in human erythrocytes. Antimicrobial Agents and Chemotherapy 38, 1144-1148.
    • (1994) Antimicrobial Agents and Chemotherapy , vol.38 , pp. 1144-1148
    • Grellier, P.1    Valentin, A.2    Milleroux, V.3    Schrevel, J.4    Rigomier, D.5
  • 30
    • 0002407096 scopus 로고
    • Lipid biochemistry of trypanosomatids
    • (G. Coombs and M. North, Eds.). Taylor & Francis, London
    • HAUGHAN, P. A., AND GOAD, L. J. 1991. Lipid biochemistry of trypanosomatids. In "Biochemical Protozoology" (G. Coombs and M. North, Eds.), pp. 312-328. Taylor & Francis, London.
    • (1991) Biochemical Protozoology , pp. 312-328
    • Haughan, P.A.1    Goad, L.J.2
  • 31
    • 0024507364 scopus 로고
    • Perturbation of sterol biosynthesis by itraconazole and ketoconazole in Leishmania mexicana mexicana infected macrophages
    • HART, D. T., LAUWERS, W. J., WILLEMSENS, G., VANDEN BOSSCHE, H., AND OPPERDOES, F. R. 1989. Perturbation of sterol biosynthesis by itraconazole and ketoconazole in Leishmania mexicana mexicana infected macrophages. Molecular and Biochemical Parasitology 33, 123-134.
    • (1989) Molecular and Biochemical Parasitology , vol.33 , pp. 123-134
    • Hart, D.T.1    Lauwers, W.J.2    Willemsens, G.3    Vanden Bossche, H.4    Opperdoes, F.R.5
  • 32
    • 0022332870 scopus 로고
    • Biosynthesis of polyisoprenoid lipids in the rat tapeworm hymenolepis diminuta
    • JOHNSON, W. J., AND CAIN, G. D. 1985. Biosynthesis of polyisoprenoid lipids in the rat tapeworm Hymenolepis diminuta. Comparative Biochemistry and Physiology 82B, 487-495.
    • (1985) Comparative Biochemistry and Physiology , vol.82 B , pp. 487-495
    • Johnson, W.J.1    Cain, G.D.2
  • 33
    • 0025114817 scopus 로고
    • Ultrastructural alterations induced by two ergosterol biosynthesis inhibitors, ketoconazole and terbinafine, on epimastigotes and amastigotes of Trypanosoma (Schizotrypanum) cruzi
    • LAZARDI, K., URBINA, J. A., AND DE SOUZA, W. 1990. Ultrastructural alterations induced by two ergosterol biosynthesis inhibitors, ketoconazole and terbinafine, on epimastigotes and amastigotes of Trypanosoma (Schizotrypanum) cruzi. Antimicrobial Agents Chemotherapy 34, 2097-2105.
    • (1990) Antimicrobial Agents Chemotherapy , vol.34 , pp. 2097-2105
    • Lazardi, K.1    Urbina, J.A.2    De Souza, W.3
  • 34
    • 0024650719 scopus 로고
    • 3-hydroxy-3-methylglutaryl coenzyme A reductase from Arabidopsis thaliana is structurally distinct from the yeast and animal enzymes
    • LEARNED, R. M., AND FINK, G. R. 1989. 3-hydroxy-3-methylglutaryl coenzyme A reductase from Arabidopsis thaliana is structurally distinct from the yeast and animal enzymes. Proceedings of the National Academy of Sciences USA 86, 2779-2783.
    • (1989) Proceedings of the National Academy of Sciences USA , vol.86 , pp. 2779-2783
    • Learned, R.M.1    Fink, G.R.2
  • 35
    • 0026043234 scopus 로고
    • The mevalonate pathway in the bloodstream form of Trypanosoma brucei. Identification of dolichols containing 11 and 12 isoprene units
    • LÖW, P., DALLNER, G., MAYOR, S., COHEN, S., CHAIT, B. T., AND MENON, A. K. 1991. The mevalonate pathway in the bloodstream form of Trypanosoma brucei. Identification of dolichols containing 11 and 12 isoprene units. The Journal of Biological Chemistry 266, 19250-19257.
    • (1991) The Journal of Biological Chemistry , vol.266 , pp. 19250-19257
    • Löw, P.1    Dallner, G.2    Mayor, S.3    Cohen, S.4    Chait, B.T.5    Menon, A.K.6
  • 36
    • 0022394722 scopus 로고
    • Human 3-hydroxy-3-methylglutaryl coenzyme A reductase: Conserved domains responsible for catalytic activity and sterolregulated degradation
    • LUSKEY, K. L., AND STEVENS, B. 1985. Human 3-hydroxy-3-methylglutaryl coenzyme A reductase: Conserved domains responsible for catalytic activity and sterolregulated degradation. The Journal of Biological Chemistry 260, 10271-10277.
    • (1985) The Journal of Biological Chemistry , vol.260 , pp. 10271-10277
    • Luskey, K.L.1    Stevens, B.2
  • 38
    • 0025630505 scopus 로고
    • Biosynthesis of glycosyl-phosphatidylinositol lipids in Trypanosoma brucei: Involvement of mannosylphosphoryldolichol as the mannose donor
    • MENON, A. K., MAYOR, S., AND SCHWARZ, R. T. 1990. Biosynthesis of glycosyl-phosphatidylinositol lipids in Trypanosoma brucei: Involvement of mannosylphosphoryldolichol as the mannose donor. EMBO Journal 9, 4249-4258.
    • (1990) EMBO Journal , vol.9 , pp. 4249-4258
    • Menon, A.K.1    Mayor, S.2    Schwarz, R.T.3
  • 39
    • 0004237567 scopus 로고
    • Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • MILLER, J. H., AND REZNIKOFF, W. S. 1980. "The Operon," 2nd ed., pp. 1-469. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
    • (1980) "The Operon," 2nd Ed. , pp. 1-469
    • Miller, J.H.1    Reznikoff, W.S.2
  • 40
    • 0019616584 scopus 로고
    • Lipid composition of metacestodes of Taenia taeniaeformis and lipid changes during growth
    • MILLS, G. L., TAYLOR, D. C., AND WILLIAMS, J. F. 1981. Lipid composition of metacestodes of Taenia taeniaeformis and lipid changes during growth. Molecular and Biochemical Parasitology 3, 301-318.
    • (1981) Molecular and Biochemical Parasitology , vol.3 , pp. 301-318
    • Mills, G.L.1    Taylor, D.C.2    Williams, J.F.3
  • 43
    • 0027227797 scopus 로고
    • Biosynthesis of protein-linked oligosaccharides in trypanosomatid flagellates
    • PARODI, A. J. 1993. Biosynthesis of protein-linked oligosaccharides in Trypanosomatid flagellates. Parasitology Today 9, 373-377.
    • (1993) Parasitology Today , vol.9 , pp. 373-377
    • Parodi, A.J.1
  • 44
    • 0028326575 scopus 로고
    • Possible localization of dolichol-dependent mannosyltransferase of Trypanosoma brucei to the rough endoplasmic reticulum
    • PRADO-FIGUEROA, M., RAPER, J., AND OPPERDOES, F. R. 1994. Possible localization of dolichol-dependent mannosyltransferase of Trypanosoma brucei to the rough endoplasmic reticulum. Molecular and Biochemical Parasitology 63, 255-264.
    • (1994) Molecular and Biochemical Parasitology , vol.63 , pp. 255-264
    • Prado-Figueroa, M.1    Raper, J.2    Opperdoes, F.R.3
  • 45
    • 0022619136 scopus 로고
    • Characterization of dolichol monophosphate- and dolichol diphosphate-linked saccharides in trypanosomatid flagellates
    • PREVIATO, J. O., MENDELZON, D. H., AND PARODI, A. J. 1986. Characterization of dolichol monophosphate- and dolichol diphosphate-linked saccharides in trypanosomatid flagellates. Molecular Biochemical Parasitology 18, 343-353.
    • (1986) Molecular Biochemical Parasitology , vol.18 , pp. 343-353
    • Previato, J.O.1    Mendelzon, D.H.2    Parodi, A.J.3
  • 46
    • 0021103812 scopus 로고
    • Novel mannose carrier in the trypanosomatid Crithidia fasciculata behaving as a short α-saturated polyprenyl phosphate
    • QUESADA-ALLUE, L. A., AND PARODI, A. J. 1983. Novel mannose carrier in the trypanosomatid Crithidia fasciculata behaving as a short α-saturated polyprenyl phosphate. The Biochemical Journal 212, 123-128.
    • (1983) The Biochemical Journal , vol.212 , pp. 123-128
    • Quesada-Allue, L.A.1    Parodi, A.J.2
  • 47
    • 0024853856 scopus 로고
    • Molecular cloning and sequence analysis of 3-hydroxy-3-methylglutaryl coenzyme a reductase from the human parasite Schistosoma mansoni
    • RAJKOVIC, A., SIMONSEN, J. N., DAVIS, R. E., AND ROTTMAN, F. M. 1989. Molecular cloning and sequence analysis of 3-hydroxy-3-methylglutaryl coenzyme A reductase from the human parasite Schistosoma mansoni. Proceedings of the National Academy of Sciences USA 86, 8217-8221.
    • (1989) Proceedings of the National Academy of Sciences USA , vol.86 , pp. 8217-8221
    • Rajkovic, A.1    Simonsen, J.N.2    Davis, R.E.3    Rottman, F.M.4
  • 48
    • 0027368126 scopus 로고
    • Isoprenoid biosynthesis in bacteria: A novel pathway for the early steps leading to isopentenyl diphosphate
    • ROHMER, M., KNANI, M., SIMONIN, P., SUTTER, B., AND SAHM, H. 1993. Isoprenoid biosynthesis in bacteria: A novel pathway for the early steps leading to isopentenyl diphosphate. Biochemical Journal 295, 517-524.
    • (1993) Biochemical Journal , vol.295 , pp. 517-524
    • Rohmer, M.1    Knani, M.2    Simonin, P.3    Sutter, B.4    Sahm, H.5
  • 49
    • 0026720521 scopus 로고
    • Immunological evidence for eight spans in the membrane domain of 3-hydroxy-3-methylglutaryl coenzyme A reductase: Implications for enzyme degradation in the endoplasmic reticulum
    • ROITELMAN, J., OLENDER, E. H., BAR-NUN, S., DUNN, W. A. D., AND SIMONI, R. D. 1992. Immunological evidence for eight spans in the membrane domain of 3-hydroxy-3-methylglutaryl coenzyme A reductase: Implications for enzyme degradation in the endoplasmic reticulum. The Journal of Cell Biology 117, 959-973.
    • (1992) The Journal of Cell Biology , vol.117 , pp. 959-973
    • Roitelman, J.1    Olender, E.H.2    Bar-Nun, S.3    Dunn, W.A.D.4    Simoni, R.D.5
  • 50
    • 0023873821 scopus 로고
    • Evidence for the occurrence of LDL receptors in extracts of schistosomula of Schistosoma mansoni
    • RUMJANEK, F. D., AND MCLAREN, D. J. 1988. Evidence for the occurrence of LDL receptors in extracts of schistosomula of Schistosoma mansoni. Molecular and Biochemical Parasitology 28, 145-152.
    • (1988) Molecular and Biochemical Parasitology , vol.28 , pp. 145-152
    • Rumjanek, F.D.1    McLaren, D.J.2
  • 52
    • 0018836491 scopus 로고
    • Trypanosoma brucei brucei: Inhibition of glycosylation of the major variable surface coat glycoprotein by tunicamycin
    • STRICKLER, J. E., AND PATTON, C. L. 1980. Trypanosoma brucei brucei: Inhibition of glycosylation of the major variable surface coat glycoprotein by tunicamycin. Proceedings of the National Academy of Sciences USA 77, 1529-1533.
    • (1980) Proceedings of the National Academy of Sciences USA , vol.77 , pp. 1529-1533
    • Strickler, J.E.1    Patton, C.L.2
  • 53
    • 0023681312 scopus 로고
    • Antiproliferative synergism of the allylamine SF-86327 and ketoconazole on epimastigotes and amastigotes of Trypanosoma (Schizotrypanum) cruzi
    • URBINA, J. A., LAZARDI, K., AGUIRRE, T., PIRAS, M. M., AND PIRAS, R. 1988a. Antiproliferative synergism of the allylamine SF-86327 and ketoconazole on epimastigotes and amastigotes of Trypanosoma (Schizotrypanum) cruzi. Antimicrobial Agents and Chemotherapy 32, 1237-1242.
    • (1988) Antimicrobial Agents and Chemotherapy , vol.32 , pp. 1237-1242
    • Urbina, J.A.1    Lazardi, K.2    Aguirre, T.3    Piras, M.M.4    Piras, R.5
  • 54
    • 0023793225 scopus 로고
    • Alteration of lipid order profile and permeability of plasma membranes from Trypanosoma cruzi epimastigotes grown in the presence of ketoconazole
    • URBINA, J. A., VIVAS, J., RAMOS, H., LARRALDE, G., AGUILAR, Z., AND AVILAN, L. 1988b. Alteration of lipid order profile and permeability of plasma membranes from Trypanosoma cruzi epimastigotes grown in the presence of ketoconazole. Molecular and Biochemical Parasitology 30, 185-196.
    • (1988) Molecular and Biochemical Parasitology , vol.30 , pp. 185-196
    • Urbina, J.A.1    Vivas, J.2    Ramos, H.3    Larralde, G.4    Aguilar, Z.5    Avilan, L.6
  • 55
    • 0027413385 scopus 로고
    • Mevinolin (lovastatin) potentiates the antiproliferative effects of ketoconazole and terbinafine against Trypanosoma (Schizotrypanum) cruzi: In vitro and in vivo studies
    • URBINA, J. A., LAZARDI, K., MARCHAN, E., VISBAL, G., AGUIRRE, T., PIRAS, M. M., MALDONADO, R. A., PAYARES, G., AND DE SOUZA, W. 1993. Mevinolin (lovastatin) potentiates the antiproliferative effects of ketoconazole and terbinafine against Trypanosoma (Schizotrypanum) cruzi: In vitro and in vivo studies. Antimicrobial Agents and Chemotherapy 37, 580-591.
    • (1993) Antimicrobial Agents and Chemotherapy , vol.37 , pp. 580-591
    • Urbina, J.A.1    Lazardi, K.2    Marchan, E.3    Visbal, G.4    Aguirre, T.5    Piras, M.M.6    Maldonado, R.A.7    Payares, G.8    De Souza, W.9
  • 56
    • 0001905791 scopus 로고
    • Antiprotozoal activity of ergosterol biosynthesis inhibitors: Focus on trypanosomatidae and plasmodiidae
    • VANDEN BOSSCHE, H. 1993. Antiprotozoal activity of ergosterol biosynthesis inhibitors: Focus on Trypanosomatidae and Plasmodiidae. Microbiology Europe, Nov/Dec, 20-28.
    • (1993) Microbiology Europe, Nov/dec , pp. 20-28
    • Vanden Bossche, H.1
  • 59
    • 0023007903 scopus 로고
    • Plasmodium falciparum: Inhibition of dolichol kinase by mefloquine
    • WALTER, R. D. 1986. Plasmodium falciparum: Inhibition of dolichol kinase by mefloquine. Experimental Parasitology 62, 356-361.
    • (1986) Experimental Parasitology , vol.62 , pp. 356-361
    • Walter, R.D.1
  • 60
    • 0024229158 scopus 로고
    • 3-hydroxy-3-methylglutaryl coenzyme A reductase of the sea urchin embryo: Deduced structure and regulatory properties
    • WOODWARD, H. D., ALLEN, J. M., AND LENNARZ, W. J. 1988. 3-hydroxy-3-methylglutaryl coenzyme A reductase of the sea urchin embryo: Deduced structure and regulatory properties. The Journal of Biological Chemistry 263, 18411-18418.
    • (1988) The Journal of Biological Chemistry , vol.263 , pp. 18411-18418
    • Woodward, H.D.1    Allen, J.M.2    Lennarz, W.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.