메뉴 건너뛰기




Volumn 33, Issue 2, 1999, Pages 295-300

SIN-1-induced cytotoxicity in cultured endothelial cells involves reactive oxygen species and nitric oxide: Protective effect of sepiapterin

Author keywords

BH4; Cell death; Hydrogen peroxide; NO; SIN 1; Superoxide; Vascular endothelial cells

Indexed keywords

HYDROGEN PEROXIDE; HYDROXYL RADICAL; IRON CHELATING AGENT; LACTATE DEHYDROGENASE; LINSIDOMINE; N ACETYLSEROTONIN; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; REACTIVE OXYGEN METABOLITE; SCAVENGER; SEPIAPTERIN; SUPEROXIDE DISMUTASE; TETRAHYDROBIOPTERIN; TRYPAN BLUE;

EID: 0032921860     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-199902000-00018     Document Type: Article
Times cited : (49)

References (33)
  • 1
    • 0020319120 scopus 로고
    • Role of oxygen-derived free radicals and metabolites in leukocyte-dependent inflammatory reactions
    • Fantone JC, Ward PA. Role of oxygen-derived free radicals and metabolites in leukocyte-dependent inflammatory reactions. Am J Pathol 1982;107:395-418.
    • (1982) Am J Pathol , vol.107 , pp. 395-418
    • Fantone, J.C.1    Ward, P.A.2
  • 2
    • 0024203618 scopus 로고
    • Role of xanthine oxidase and granulocytes in ischemia-reperfusion injury
    • Granger DN. Role of xanthine oxidase and granulocytes in ischemia-reperfusion injury. Am J Physiol 1988;255:H1269-75.
    • (1988) Am J Physiol , vol.255
    • Granger, D.N.1
  • 3
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology, and pharmacology
    • Moncada S, Palmer RMJ, Higgs EA. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev 1991;43: 109-12.
    • (1991) Pharmacol Rev , vol.43 , pp. 109-112
    • Moncada, S.1    Palmer, R.M.J.2    Higgs, E.A.3
  • 4
    • 0025189864 scopus 로고
    • Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide
    • Beckman JS, Beckman TW, Chen J, Marshall PA, Freeman BA. Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide. Proc Natl Acad Sci U S A 1990;87:1620-4.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 1620-1624
    • Beckman, J.S.1    Beckman, T.W.2    Chen, J.3    Marshall, P.A.4    Freeman, B.A.5
  • 5
    • 0025874048 scopus 로고
    • Peroxynitrite-induced membrane lipid peroxidation: The cytotoxic potential of superoxide and nitric oxide
    • Radi F, Beckman JS, Bush KM, Freeman BA. Peroxynitrite-induced membrane lipid peroxidation: the cytotoxic potential of superoxide and nitric oxide. Arch Biochem Biophys 1991;288:481-7.
    • (1991) Arch Biochem Biophys , vol.288 , pp. 481-487
    • Radi, F.1    Beckman, J.S.2    Bush, K.M.3    Freeman, B.A.4
  • 6
    • 0028151406 scopus 로고
    • Nitric oxide regulation of superoxide and peroxynitrite-dependent lipid peroxidation
    • Rubbo H, Radi P, Trujillo M, et al. Nitric oxide regulation of superoxide and peroxynitrite-dependent lipid peroxidation. J Biol Chem 1994;269;26066-75.
    • (1994) J Biol Chem , vol.269 , pp. 26066-26075
    • Rubbo, H.1    Radi, P.2    Trujillo, M.3
  • 7
    • 0031010584 scopus 로고    scopus 로고
    • Formation of nitric oxide, superoxide, and peroxynitrite in myocardial ischemia-reperfusion injury in rats
    • Liu P, Hock CE, Nagele R, Wong PYK. Formation of nitric oxide, superoxide, and peroxynitrite in myocardial ischemia-reperfusion injury in rats. Am J Physiol 1997;272:H2327-36.
    • (1997) Am J Physiol , vol.272
    • Liu, P.1    Hock, C.E.2    Nagele, R.3    Wong, P.Y.K.4
  • 8
    • 0031015688 scopus 로고    scopus 로고
    • Generation of peroxynitrite contributes to ischemia-reperfusion injury in isolated rat hearts
    • Yasmin W, Strynadka KD, Schulz R. Generation of peroxynitrite contributes to ischemia-reperfusion injury in isolated rat hearts. Cardiovasc Res 1997;33:422-32.
    • (1997) Cardiovasc Res , vol.33 , pp. 422-432
    • Yasmin, W.1    Strynadka, K.D.2    Schulz, R.3
  • 9
    • 0029129972 scopus 로고
    • Reactive species in ischemic rat lung injury: Contribution of peroxynitrite
    • Ischiropoulos H, Al-Mehdi AB, Fisher AB. Reactive species in ischemic rat lung injury: contribution of peroxynitrite. Am J Physiol 1995;269:L158-64.
    • (1995) Am J Physiol , vol.269
    • Ischiropoulos, H.1    Al-Mehdi, A.B.2    Fisher, A.B.3
  • 10
    • 0030599172 scopus 로고    scopus 로고
    • Brain nitrite production during global ischemia and reperfusion: An in vivo microdialysis study
    • Shibata M, Araki N, Hamada J, Sasaki T, Shimazu K, Fukuuchi Y. Brain nitrite production during global ischemia and reperfusion: an in vivo microdialysis study. Brain Res 1996;734:86-90.
    • (1996) Brain Res , vol.734 , pp. 86-90
    • Shibata, M.1    Araki, N.2    Hamada, J.3    Sasaki, T.4    Shimazu, K.5    Fukuuchi, Y.6
  • 11
    • 0032472217 scopus 로고    scopus 로고
    • Consecutive evaluation of nitric oxide production after transient cerebral ischemia in the rat hippocampus using in vivo brain microdialysis
    • Togashi H, Mori K, Ueno K, Matsumoto M, Suda N, Saito H, Yoshioka M. Consecutive evaluation of nitric oxide production after transient cerebral ischemia in the rat hippocampus using in vivo brain microdialysis. Neurosci Lett 1998;240:53-7.
    • (1998) Neurosci Lett , vol.240 , pp. 53-57
    • Togashi, H.1    Mori, K.2    Ueno, K.3    Matsumoto, M.4    Suda, N.5    Saito, H.6    Yoshioka, M.7
  • 12
    • 0026554894 scopus 로고
    • Cardioprotection and attenuation of endothelial dysfunction by organic nitric oxide donors in myocardial ischemia-reperfusion
    • Siegfried MR, Erhardt J, Rider T, MA X-L, Lefer AM. Cardioprotection and attenuation of endothelial dysfunction by organic nitric oxide donors in myocardial ischemia-reperfusion. J Pharmacol Exp Ther 1992;260:668-75.
    • (1992) J Pharmacol Exp Ther , vol.260 , pp. 668-675
    • Siegfried, M.R.1    Erhardt, J.2    Rider, T.3    Ma, X.-L.4    Lefer, A.M.5
  • 13
    • 0027431768 scopus 로고
    • Endothelial and myocardial cell protection by a cysteine-containing nitric oxide donor after myocardial ischemia and reperfusion
    • Lefer DJ, Nakanishi K, Vinten-Johansen J. Endothelial and myocardial cell protection by a cysteine-containing nitric oxide donor after myocardial ischemia and reperfusion. J Cardiovasc Pharmacol 1993;22(suppl 7):S34-43.
    • (1993) J Cardiovasc Pharmacol , vol.22 , Issue.7 SUPPL.
    • Lefer, D.J.1    Nakanishi, K.2    Vinten-Johansen, J.3
  • 14
    • 0027952964 scopus 로고
    • Modulation of ischemia/reperfusion-induced microvascular dysfunction by nitric oxide
    • Kurose I, Wolf R, Grisham MB, Granger DN. Modulation of ischemia/reperfusion-induced microvascular dysfunction by nitric oxide. Circ Res 1994;74:376-82.
    • (1994) Circ Res , vol.74 , pp. 376-382
    • Kurose, I.1    Wolf, R.2    Grisham, M.B.3    Granger, D.N.4
  • 15
    • 0023912670 scopus 로고
    • Vascular endothelial cells synthesize nitric oxide from L-arginine
    • Palmer RMJ, Ashton DS, Moncada S. Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature 1988;333:664-6.
    • (1988) Nature , vol.333 , pp. 664-666
    • Palmer, R.M.J.1    Ashton, D.S.2    Moncada, S.3
  • 16
    • 0024816829 scopus 로고
    • Modulation of arterial endothelial permeability: Studies on an in vitro model
    • Gudgeon JR, Martin W. Modulation of arterial endothelial permeability: studies on an in vitro model. Br J Pharmacol 1989;98:1267-74.
    • (1989) Br J Pharmacol , vol.98 , pp. 1267-1274
    • Gudgeon, J.R.1    Martin, W.2
  • 17
    • 0030738911 scopus 로고    scopus 로고
    • Acceleration of oxidative stress-induced endothelial cell death by nitric oxide synthase dysfunction accompanied with decrease in tetrahydrobiopterin content
    • Ishii M, Shimizu S, Yamamoto T, Momose K, Kuroiwa Y. Acceleration of oxidative stress-induced endothelial cell death by nitric oxide synthase dysfunction accompanied with decrease in tetrahydrobiopterin content. Life Sci 1997;61:739-47.
    • (1997) Life Sci , vol.61 , pp. 739-747
    • Ishii, M.1    Shimizu, S.2    Yamamoto, T.3    Momose, K.4    Kuroiwa, Y.5
  • 19
    • 0029056897 scopus 로고
    • Antioxidative activity of 5,6,7,8,-tetrahydrobiopterin and its inhibitory effect on paraquat-induced cell toxicity in cultured rat hepatocytes
    • Kojima S, Ona S, Iizuka I, Arai T, Mori H, Kubota K. Antioxidative activity of 5,6,7,8,-tetrahydrobiopterin and its inhibitory effect on paraquat-induced cell toxicity in cultured rat hepatocytes. Free Radic Res 1995;23:419-30.
    • (1995) Free Radic Res , vol.23 , pp. 419-430
    • Kojima, S.1    Ona, S.2    Iizuka, I.3    Arai, T.4    Mori, H.5    Kubota, K.6
  • 21
    • 0030932524 scopus 로고    scopus 로고
    • Possible involvement of nitric oxide synthase in oxidative stress-induced endothelial cell injury
    • Ishii M, Yamamoto T, Shimizu S, Sano A, Momose K, Kuroiwa Y. Possible involvement of nitric oxide synthase in oxidative stress-induced endothelial cell injury. Pharmacol Toxicol 1997;80:191-6.
    • (1997) Pharmacol Toxicol , vol.80 , pp. 191-196
    • Ishii, M.1    Yamamoto, T.2    Shimizu, S.3    Sano, A.4    Momose, K.5    Kuroiwa, Y.6
  • 22
    • 0018868814 scopus 로고
    • Analysis of reduced forms of biopterin in biological tissues and fluids
    • Fukushima T, Nixon JC. Analysis of reduced forms of biopterin in biological tissues and fluids. Anal Biochem 1980;102:176-88.
    • (1980) Anal Biochem , vol.102 , pp. 176-188
    • Fukushima, T.1    Nixon, J.C.2
  • 23
    • 0029787902 scopus 로고    scopus 로고
    • Self-limiting enhancement by nitric oxide of oxygen free radical-induced endothelial cell injury: Evidence against the dual action of NO as hydroxyl radical donor/scavenger
    • Az-ma T, Fujii K, Yuge O. Self-limiting enhancement by nitric oxide of oxygen free radical-induced endothelial cell injury: evidence against the dual action of NO as hydroxyl radical donor/scavenger. Br J Pharmacol 1996;119:455-62.
    • (1996) Br J Pharmacol , vol.119 , pp. 455-462
    • Az-ma, T.1    Fujii, K.2    Yuge, O.3
  • 25
    • 0029959717 scopus 로고    scopus 로고
    • DNA strand breakage and activation of poly-ADP ribosyltransferase: A cytotoxic pathway triggered by peroxynitrite
    • Szabo C. DNA strand breakage and activation of poly-ADP ribosyltransferase: a cytotoxic pathway triggered by peroxynitrite. Free Radic Biol Med 1996;21:855-69.
    • (1996) Free Radic Biol Med , vol.21 , pp. 855-869
    • Szabo, C.1
  • 26
  • 27
    • 0030885658 scopus 로고    scopus 로고
    • Nitric oxide- and superoxide-mediated toxicity in cerebral endothelial cells
    • Gobbel GT, Chan TY-Y, Chan PH. Nitric oxide- and superoxide-mediated toxicity in cerebral endothelial cells. J Pharmacol Exp Ther 1997;282:1600-7.
    • (1997) J Pharmacol Exp Ther , vol.282 , pp. 1600-1607
    • Gobbel, G.T.1    Chan, T.Y.-Y.2    Chan, P.H.3
  • 28
    • 0029099103 scopus 로고
    • Inactivation of glutathione peroxidase by nitric oxide: Implication for cytotoxicity
    • Asahi M, Fujii J, Suzuki K, et al. Inactivation of glutathione peroxidase by nitric oxide: implication for cytotoxicity. J Biol Chem 1995;270:21035-9.
    • (1995) J Biol Chem , vol.270 , pp. 21035-21039
    • Asahi, M.1    Fujii, J.2    Suzuki, K.3
  • 29
    • 0030805135 scopus 로고    scopus 로고
    • The oxidation of selenocysteine is involved in the inactivation of glutathione peroxidase by nitric oxide donor
    • Asahi M, Fujii J, Takao T, et al. The oxidation of selenocysteine is involved in the inactivation of glutathione peroxidase by nitric oxide donor. J Biol Chem 1997;272:19152-7.
    • (1997) J Biol Chem , vol.272 , pp. 19152-19157
    • Asahi, M.1    Fujii, J.2    Takao, T.3
  • 30
    • 0030942089 scopus 로고    scopus 로고
    • Modulation of S-nitroso-N-acetyl-D,L-penicillamine (SNAP) induced HL-60 cell death by tetrahydrobiopterin
    • Kojima S, Nimura K, Komatsu H, Taguchi T, Iizuka H. Modulation of S-nitroso-N-acetyl-D,L-penicillamine (SNAP) induced HL-60 cell death by tetrahydrobiopterin. Anticancer Res 1997;17:929-38.
    • (1997) Anticancer Res , vol.17 , pp. 929-938
    • Kojima, S.1    Nimura, K.2    Komatsu, H.3    Taguchi, T.4    Iizuka, H.5
  • 31
    • 0026584089 scopus 로고
    • 2+/calmodulin-dependent formation of hydrogen peroxide by brain nitric oxide synthase
    • 2+/calmodulin-dependent formation of hydrogen peroxide by brain nitric oxide synthase. Biochem J 1992;281:627-30.
    • (1992) Biochem J , vol.281 , pp. 627-630
    • Heinzel, B.1    John, M.2    Klatt, P.3    Böhme, E.4    Mayer, B.5
  • 32
    • 0026556496 scopus 로고
    • Tetrahydrobiopterin-dependent formation of endothelium-derived relaxing factor (nitric oxide) in aortic endothelial cells
    • Schmidt K, Werner ER, Mayer B, Wachter H, Kukovetz WR. Tetrahydrobiopterin-dependent formation of endothelium-derived relaxing factor (nitric oxide) in aortic endothelial cells. Biochem J 1992;281:297-300.
    • (1992) Biochem J , vol.281 , pp. 297-300
    • Schmidt, K.1    Werner, E.R.2    Mayer, B.3    Wachter, H.4    Kukovetz, W.R.5
  • 33
    • 0028813306 scopus 로고
    • Tetrahydrobiopterin and dysfunction of endothelial nitric oxide synthase in coronary arteries
    • Cosentino F, Katusic ZS. Tetrahydrobiopterin and dysfunction of endothelial nitric oxide synthase in coronary arteries. Circulation 1995;91:139-44.
    • (1995) Circulation , vol.91 , pp. 139-144
    • Cosentino, F.1    Katusic, Z.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.