|
|
Volumn 20, Issue 57, 2001, Pages 8203-8214
|
|
Aberrant expression and activation of insulin-like growth factor-1 receptor (IGF-1R) are mediated by an induction of IGF-1R promoter activity and stabilization of IGF-1R mRNA and contributes to growth factor independence and increased survival of the pancreatic cancer cell line MIA PaCa-2
|
|
Author keywords
Apoptosis; Growth regulation; IGF 1R; Pancreatic cancer; Signal transduction
|
|
Indexed keywords
GROWTH FACTOR;
MESSENGER RNA;
SOMATOMEDIN C RECEPTOR;
ARTICLE;
CANCER CELL CULTURE;
CELL SURVIVAL;
CONTROLLED STUDY;
GENE INDUCTION;
PANCREAS CANCER;
PRIORITY JOURNAL;
PROMOTER REGION;
PROTEIN EXPRESSION;
RNA STABILITY;
1-PHOSPHATIDYLINOSITOL 3-KINASE;
APOPTOSIS;
CELL DIVISION;
CELL SURVIVAL;
CULTURE MEDIA, SERUM-FREE;
GENE EXPRESSION REGULATION, NEOPLASTIC;
GROWTH SUBSTANCES;
HUMANS;
INSULIN-LIKE GROWTH FACTOR I;
MITOGEN-ACTIVATED PROTEIN KINASES;
PANCREATIC NEOPLASMS;
PROMOTER REGIONS (GENETICS);
RECEPTOR, IGF TYPE 1;
RNA STABILITY;
RNA, MESSENGER;
RNA, NEOPLASM;
SIGNAL TRANSDUCTION;
TRANS-ACTIVATION (GENETICS);
TUMOR CELLS, CULTURED;
AGOUTI PACA;
|
|
EID: 0035857042
PISSN: 09509232
EISSN: None
Source Type: Journal
DOI: 10.1038/sj.onc.1205044 Document Type: Article |
|
Times cited : (71)
|
|
References (50)
|
