Regulation of transforming growth factor expression in a growth factor- independent cell line

Molecular and Cellular Biology

Volumn 18, Issue 1, 1998, Pages 303-313

  Howell, Gillian M ^a,e   Humphrey, Lisa E ^a,e   Ziober, Barry L ^b   Awwad, Rana ^a   Periyasamy, Basker ^a   Koterba, Alan ^a   Li, Wenhui ^a,e   Willson, James K V ^c   Coleman, Kevin ^d   Carboni, Joan ^d   Lynch, Mark ^d   Brattain, Michael G ^a,e  

^a MEDICAL COLLEGE OF OHIO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c CASE WESTERN RESERVE UNIVERSITY   (United States)

^d BRISTOL MYERS SQUIBB   (United States)

^e UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; COMPLEMENTARY RNA; DNA; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; GROWTH FACTOR; MESSENGER RNA; TRANSFORMING GROWTH FACTOR ALPHA;

ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; HUMAN; HUMAN CELL; MALIGNANT NEOPLASTIC DISEASE; PHENOTYPE; PRIORITY JOURNAL; TRANSCRIPTION REGULATION;

EID: 17144464934     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.18.1.303     Document Type: Article

References (47)

1. Angel, P., M. Imagawa, R. Chiu, B. Stein, R. J. Imbra, H. J. Rahmsdorf, C. Jonat, P. Herrlich, and M. Karin. 1987. Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor. Cell 49:729-739.
2. Bjorge, J. D., A. J. Paterson, and J. E. Kudlow. 1989. Phorbol ester or epidermal growth factor (EGF) stimulates the concurrent accumulation of mRNA for the EGF receptor and its ligand transforming growth factor-α in a breast cancer cell line. J. Biol. Chem. 264:4021-4027.
3. Blasband, A. J., K. T. Rogers, X. Chen, J. C. Azizkhan, and D. C. Lee. 1990. Characterization of the rat transforming growth factor alpha gene and identification of promoter sequences. Mol. Cell. Biol. 10:2111-2121.
4. Boyd, D. D., A. E. Levine, D. E. Brattain, M. K. McKnight, and M. G. Brattain. 1988. A comparison of growth requirements for two human intratumoral colon carcinoma cell lines in monolayer and soft agarose. Cancer Res. 48:2469-2474.
5. Cao, X., R. A. Koski, A. Gashler, M. McKiernan, C. F. Morris, R. Gaffney, R. V. Hay, and V. P. Sukhatme. 1990. Identification and characterization of the Egr-1 gene product, a DNA-binding zinc finger protein induced by differentiation and growth signals. Mol. Cell. Biol. 10:1931-1939.
6. Carpenter, G., and S. Cohen. 1990. Epidermal growth factor. J. Biol. Chem. 265:7709-7712.
7. Chirgwin, J. M., A. E. Przybyla, R. J. Mackondla, and W. J. Rutter. 1979. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 18:5294-5299.
8. Coffey, R. J., R. Derynck, J. N. Wilcox, T. S. Bringman, A. S. Goustin, H. L. Moses, and M. R. Pittelkow. 1987. Production and auto-induction of transforming growth factor-α in human keratinocytes. Nature 328:817-820.
9. Coffey, R. J., Jr., R. Graves-Deal, P. J. Dempsey, R. H. Whitehead, and M. R. Pittelkow. 1992. Differential regulation of transforming growth factor α autoinduction in a non-transformed and transformed epithelial cell. Cell Growth Differ. 3:347-354.
10. Curran, T., and B. R. Franza, Jr. 1988. Fos and Jun: the AP-1 connection. Cell 55:395-397.
11. DeLarco, J. E., and G. J. Todaro. 1978. Growth factors from murine sarcoma virus-transformed cell. Proc. Natl. Acad. Sci. USA 75:4001-4005.
12. Derynck, R. 1992. The physiology of transforming growth factor-α. Adv. Cancer Res. 58:27-52.
13. Derynck, R., D. V. Goeddel, A. Ullrich, J. U. Gutterman, R. D. Williams, T. S. Bringman, and W. H. Berger. 1987. Synthesis of messenger RNAs for transforming growth factors α and β and the epidermal growth factor receptor by human tumors. Cancer Res. 47:707-712.
14. Dignam, J. D., R. M. Lebowitz, and R. G. Roeder. 1983. Accurate transcription initiation by polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1475-1489.
15. Elsholtz, H. P., H. J. Mangalam, E. Potter, V. R. Albert, S. Supowit, R. M. Evans, and M. G. Rosenfeld. 1986. Two different cis-active elements transfer the transcriptional effects of both EGF and phorbol esters. Science 234: 1552-1557.
16. Ennis, B. W., E. M. Valverius, S. E. Bates, M. E. Lippman, F. Bellot, R. Kris, J. Schlessinger, H. Masui, A. Goldenberg, J. Mendelsohn, and R. B. Dickson. 1989. Anti-epidermal growth factor receptor antibodies inhibit the autocrine-stimulated growth of MDA-468 human breast cancer cells. Mol. Endocrinol. 3:1830-1838.
17. Fisch, T. M., R. Prywes, and R. G. Roeder. 1989. An AP1-binding site in the c-fos gene can mediate induction by epidermal growth factor and 12-O-tetradecanoyl phorbol-13-acetate. Mol. Cell. Biol. 9:1327-1331.
18. Gorski, K., M. Carneiro, and U. Schibler. 1986. Tissue-specific in vitro transcription from the mouse albumin promoter. Cell 47:767-776.
19. Greenberg, M. E., A. L. Hermanowski, and E. B. Ziff. 1986. Effect of protein synthesis inhibitors on growth factor activation of c-fos, c-myc, and actin gene transcription. Mol. Cell. Biol. 6:1050-1057.
20. Greenberg, M. E., and E. B. Ziff. 1984. Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene. Nature 311:433-438.
21. Howell, G. M., B. L. Ziober, L. E. Humphrey, J. K. V. Willson, L. Sun, M. Lynch, and M. G. Brattain. 1995. Regulation of autocrine gastrin expression by the TGFα autocrine loop. J. Cell. Physiol. 162:256-265.
22. Hudson, L. G., K. L. Thompson, J. Xu, and G. N. Gill. 1990. Identification and characterization of a regulated promoter element in the epidermal growth factor receptor gene. Proc. Natl. Acad. Sci. USA 87:7536-7540.
23. Imanishi, K.-I., K. Yamaguchi, M. Kuranami, E. Kyo, T. Hozumi, and K. Abe. 1989. Inhibition of growth of human lung adenocarcinoma cell lines by anti-transforming growth factor-α monoclonal antibody. J. Natl. Cancer Inst. 81:220-223.
24. Jakobovits, E. B., U. Schlokat, J. L. Vannice, R. Derynck, and A. D. Levinson. 1988. The human transforming growth factor alpha promoter directs initiation from a single site in the absence of a TATA sequence. Mol. Cell. Biol. 8:5549-5554.
25. Lee, L. W., V. W. Raymond, M.-S. Tsao, D. C. Lee, H. S. Earp, and J. W. Grisham. 1991. Clonal cosegregation of tumorigenicity with overexpression of c-myc and transforming growth factor α genes in chemically transformed rat liver epithelial cells. Cancer Res. 51:5238-5244.
26. Lewis, E. J., and D. M. Chikaraishi. 1987. Regulated expression of the tyrosine hydroxylase gene by epidermal growth factor. Mol. Cell. Biol. 7: 3332-3336.
27. Lynch, M. J., L. Pelosi, J. M. Carboni, J. Merwin, K. Coleman, R. R. C. Wang, P. F. M. Lin, and M. G. Brattain. 1994. Transforming growth factor β1 induces transforming growth factor-α (TGFα) promoter activity and TGFα secretion in the human colon adenocarcinoma cell line FET. Cancer Res. 53:4041-4047.
28. Malden, L. T., U. Novak, and A. W. Burgess. 1989. Expression of transforming growth factor alpha messenger RNA in the normal and neoplastic gastrointestinal tract. Int. J. Cancer 43:380-384.
29. Maniatis, T., E. F. Fritsch, and J. Sambrook. 1982. Molecular cloning: a laboratory manual, p. 202-203. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
30. McDonnell, S. E., L. D. Kerr, and L. M. Matrisian. 1990. Epidermal growth factor stimulation of stromelysin mRNA in rat fibroblasts requires induction of proto-oncogenes c-fos and c-jun and activation of protein kinase C. Mol. Cell. Biol. 10:4284-4293.
31. Markowitz, S. D., K. Molkentin, C. Gerbic, J. Jackson, T. Stellato, and J. K. V. Willson. 1990. Growth stimulation by co-expression of transforming growth factor-α and epidermal growth factor-receptor in normal and adenomatous human colon epithelium. J. Clin. Invest. 86:356-362.
32. Merchant, J. L., B. Demediuk, and S. J. Brand. 1991. A GC-rich element confers epidermal growth factor responsiveness to transcription from the gastrin promoter. Mol. Cell. Biol. 11:2686-2696.
33. Mulder, K. M., and M. G. Brattain. 1989. Effects of growth stimulatory factors on mitogenicity and c-myc expression in poorly differentiated and well differentiated human colon carcinoma cells. Mol. Endocrinol. 3:1215-1222.
34. Mulder, K. M., and M. G. Brattain. 1989. Growth factor expression and response in human colon carcinoma cells, p. 45-67. In L. Augenlicht (ed.), The cell and molecular biology of colon cancer. CRC Press, Boca Raton, Fla.
35. Pittelkow, M. R., P. B. Lindquist, R. T. Abraham, R. Graves-Deal, R. Derynk, and R. J. Coffey. 1989. Induction of transforming growth factor-α expression in human keratinocytes by phorbol esters. J. Biol. Chem. 264: 5164-5171.
36. Raja, R. H., A. J. Paterson, T. H. Shin, and J. E. Kudlow. 1991. Transcriptional regulation of the human transforming growth factor-α gene. Mol. Endocrinol. 5:514-520.
37. Saeki, T., A. Gistiano, M. J. Lynch, M. Brattain, N. Kim, N. Normanno, N. Kenney, F. Ciardiello, and D. S. Salomon. 1991. Regulation by estrogen through the 5′-flanking region of the transforming growth factor α gene. Mol. Endocrinol. 5:1955-1963.
38. Scheidereit, C., A. Heguy, and R. G. Roeder. 1987. Identification and purification of a human lymphoid-specific octamer-binding protein (OTF-2) that activates transcription of an immunoglobulin promoter in vitro. Cell 51:783-793.
39. Sizeland, A. M., and A. W. Burgess. 1991. The proliferative and morphologic responses of a colon carcinoma cell line (LIM 1215) require the production of two autocrine factors. Mol. Cell. Biol. 11:4005-4014.
40. Sizeland, A. M., and A. W. Burgess. 1992. Anti-sense transforming growth factor α oligonucleotides inhibit autocrine stimulated proliferation of a colon carcinoma cell line. Mol. Biol. Cell 3:1235-1243.
41. Sporn, M. B., and A. B. Roberts. 1985. Introduction: autocrine, paracrine and endocrine mechanisms of growth control. Cancer Surv. 4:627-632.
42. Sporn, M. B., and A. B. Roberts. 1985. Autocrine growth factors and cancers. Nature 313:745-747.
43. Sporn, M. B., and G. J. Todaro. 1980. Autocrine secretion and malignant transformation of cells. N. Engl. J. Med. 303:878-880.
44. Sukhatme, V. P. 1991. The Egr family of nuclear signal transducers. Am. J. Kidney Dis. 17:615-618.
45. Todaro, G. J., T. M. Rose, C. E. Spooner, M. Shoyab, and G. D. Plowman. 1990. Cellular and viral ligands that interact with the EGF receptor. Semin. Cancer Biol. 1:257-263.
46. Wan, C.-W., K. M. McKnight, D. E. Brattain, M. G. Brattain, and L. C. Yeoman. 1988. Growth requirements and receptor levels for epidermal growth factor in human colon carcinoma cell lines. Cancer Lett. 43:139-145.
47. Ziober, B. L., J. K. V. Willson, L. E. Humphrey, K. Childress-Fields, and M. G. Brattain. 1993. Autocrine transforming growth factor-α is associated with progression of transformed properties in human colon cancer cells. J. Biol. Chem. 268:691-698.