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Volumn 53, Issue 6, 1997, Pages 865-875

Activation of protein kinase C subtypes α, γ, δ, ε, ζ, and η by tumor-promoting and nontumor-promoting agents

Author keywords

bryostatin 1; indolactam V; mezerein; protein kinase C; sapintoxin D; tumor promoters

Indexed keywords

BRYOSTATIN 1; INDOLACTAM V; ISOENZYME; K 252A; MEZEREIN; MIDOSTAURIN; PHORBOL ESTER; PROTEIN KINASE C; RECOMBINANT PROTEIN; RESINIFERATOXIN; SAPINTOXIN D; STAUROSPORINE; THAPSIGARGIN; TINYATOXIN; UNCLASSIFIED DRUG; VIRUS VECTOR;

EID: 0030949418     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(96)00885-4     Document Type: Article
Times cited : (91)

References (53)
  • 2
    • 0027322679 scopus 로고
    • Protein kinase C isoenzymes: Divergence in signal transduction?
    • Hug H and Sarre TF, Protein kinase C isoenzymes: Divergence in signal transduction? Biochem J 291: 329-343, 1993.
    • (1993) Biochem J , vol.291 , pp. 329-343
    • Hug, H.1    Sarre, T.F.2
  • 4
    • 0027431089 scopus 로고
    • Molecular cloning and characterization of PKC, an atypical isoform of protein kinase C derived from insulin-secreting cells
    • Selbie LA, Schmitz-Pfeiffer C, Sheng Y and Biden TJ, Molecular cloning and characterization of PKC, an atypical isoform of protein kinase C derived from insulin-secreting cells. J Biol Chem 268: 24296-24302, 1993.
    • (1993) J Biol Chem , vol.268 , pp. 24296-24302
    • Selbie, L.A.1    Schmitz-Pfeiffer, C.2    Sheng, Y.3    Biden, T.J.4
  • 5
    • 0028298476 scopus 로고
    • A new member of the third class in the protein kinase C family, PKC λ, expressed dominantly in an undifferentiated mouse embryonal carcinoma cell line and also in many tissues and cells
    • Akimoto K, Mizuno K, Osada S-i, Hirai S-i, Tanuma S-i, Suzuki K and Ohno S, A new member of the third class in the protein kinase C family, PKC λ, expressed dominantly in an undifferentiated mouse embryonal carcinoma cell line and also in many tissues and cells. J Biol Chem 269: 12677-12683, 1994.
    • (1994) J Biol Chem , vol.269 , pp. 12677-12683
    • Akimoto, K.1    Mizuno, K.2    Osada, S.-I.3    Hirai, S.-I.4    Tanuma, S.-I.5    Suzuki, K.6    Ohno, S.7
  • 6
    • 0009484240 scopus 로고
    • PKC and cellular transformation
    • Eds. Lester D and Epand R. Ellis Horwood Series in Biochemistry and Biotechnology, Chichester
    • Borner C and Fabbro D, PKC and cellular transformation. In: Protein Kinase C: Current Concepts and Future Perspectives (Eds. Lester D and Epand R), pp. 297-354. Ellis Horwood Series in Biochemistry and Biotechnology, Chichester, 1992.
    • (1992) Protein Kinase C: Current Concepts and Future Perspectives , pp. 297-354
    • Borner, C.1    Fabbro, D.2
  • 7
    • 0025951511 scopus 로고
    • Possible regulatory functions of protein kinase C-α and -ε isoenzymes in rat renal mesangial cells
    • Huwiler A, Fabbro D and Pfeilschifter J, Possible regulatory functions of protein kinase C-α and -ε isoenzymes in rat renal mesangial cells. Biochem J 279: 441-445, 1991.
    • (1991) Biochem J , vol.279 , pp. 441-445
    • Huwiler, A.1    Fabbro, D.2    Pfeilschifter, J.3
  • 8
    • 0027070452 scopus 로고
    • Effect of tumourpromoting phorbol ester, thrombin and vasopressin on translocation of three distinct protein kinase C isoforms in human platelets and regulation by calcium
    • Crabos M, Fabbro D, Stabel S and Erne P, Effect of tumourpromoting phorbol ester, thrombin and vasopressin on translocation of three distinct protein kinase C isoforms in human platelets and regulation by calcium. Biochem J 288: 891-896, 1992.
    • (1992) Biochem J , vol.288 , pp. 891-896
    • Crabos, M.1    Fabbro, D.2    Stabel, S.3    Erne, P.4
  • 9
    • 0026451081 scopus 로고
    • Intracellular signalling by hydrolysis of phospholipids and activation of protein kinase C
    • Nishizuka Y, Intracellular signalling by hydrolysis of phospholipids and activation of protein kinase C. Science 258: 607-613, 1992.
    • (1992) Science , vol.258 , pp. 607-613
    • Nishizuka, Y.1
  • 10
    • 0022407093 scopus 로고
    • Cell membrane associated protein kinase C as receptor of diterpene ester co-carcinogens of the tumor promoter type and the phenotypic expression of tumors
    • Hecker E, Cell membrane associated protein kinase C as receptor of diterpene ester co-carcinogens of the tumor promoter type and the phenotypic expression of tumors. Arzneimforsch/Drug Res 35: 1890-1903, 1985.
    • (1985) Arzneimforsch/Drug Res , vol.35 , pp. 1890-1903
    • Hecker, E.1
  • 11
    • 0020326790 scopus 로고
    • Direct activation of calcium-activated, phospho-lipid-dependent protein kinase by tumour-promoting phorbol esters
    • Castagna M, Takai Y, Kaibuchi K, Sano K, Kikkawa U and Nishizuka Y, Direct activation of calcium-activated, phospho-lipid-dependent protein kinase by tumour-promoting phorbol esters. J Biol Chem 257: 7847-7851, 1982.
    • (1982) J Biol Chem , vol.257 , pp. 7847-7851
    • Castagna, M.1    Takai, Y.2    Kaibuchi, K.3    Sano, K.4    Kikkawa, U.5    Nishizuka, Y.6
  • 12
    • 0025228948 scopus 로고
    • 125I]EGF binding and stimulate the phosphorylation of an 80 kd protein kinase C substrate protein in intact quiescent Swiss 3T3 cells
    • 125I]EGF binding and stimulate the phosphorylation of an 80 kd protein kinase C substrate protein in intact quiescent Swiss 3T3 cells. Carcinogenesis 11: 667-672, 1990.
    • (1990) Carcinogenesis , vol.11 , pp. 667-672
    • Brooks, G.1    Brooks, S.F.2
  • 13
    • 0018407855 scopus 로고
    • Investigations into the skin-irritant properties of resiniferonol ortho esters
    • Schmidt RJ and Evans FJ, Investigations into the skin-irritant properties of resiniferonol ortho esters. Inflammation 3: 273-280, 1979.
    • (1979) Inflammation , vol.3 , pp. 273-280
    • Schmidt, R.J.1    Evans, F.J.2
  • 14
    • 0024833063 scopus 로고
    • Structure-activity analysis of resiniferatoxin analogs
    • Szallasi A, Sharkey N and Blumberg PM, Structure-activity analysis of resiniferatoxin analogs. Phytother Res 3: 253-257, 1989.
    • (1989) Phytother Res , vol.3 , pp. 253-257
    • Szallasi, A.1    Sharkey, N.2    Blumberg, P.M.3
  • 15
    • 0021751909 scopus 로고
    • Structure-activity studies on synthetic analogues (indolactams) of the tumor promoter teleocidin
    • Fujiki H, Saganuma M, Nakayasu M, Tahira T, Endo Y, Shudo K and Sugimura T, Structure-activity studies on synthetic analogues (indolactams) of the tumor promoter teleocidin. Gann 75: 866-870, 1984.
    • (1984) Gann , vol.75 , pp. 866-870
    • Fujiki, H.1    Saganuma, M.2    Nakayasu, M.3    Tahira, T.4    Endo, Y.5    Shudo, K.6    Sugimura, T.7
  • 16
    • 0022410234 scopus 로고
    • Bryostatin, a non-phorbol macrocyclic lactone, activates intact human polymorphonuclear leukocytes and binds to the phorbol ester receptor
    • Berkow RL and Kraft AS, Bryostatin, a non-phorbol macrocyclic lactone, activates intact human polymorphonuclear leukocytes and binds to the phorbol ester receptor. Biochem Biophys Res Commun 131: 1109-1116, 1985.
    • (1985) Biochem Biophys Res Commun , vol.131 , pp. 1109-1116
    • Berkow, R.L.1    Kraft, A.S.2
  • 17
    • 0023912339 scopus 로고
    • Bryostatin 1, an activator of protein kinase C, mimics as well as inhibits biological effects of the phorbol ester TPA in vivo and in vitro
    • Gschwendt M, Fürstenberger G, Rose-John S, Rogers M, Kittstein W, Pettit GR, Herald CL and Marks F, Bryostatin 1, an activator of protein kinase C, mimics as well as inhibits biological effects of the phorbol ester TPA in vivo and in vitro. Carcinogenesis 9: 555-562, 1988.
    • (1988) Carcinogenesis , vol.9 , pp. 555-562
    • Gschwendt, M.1    Fürstenberger, G.2    Rose-John, S.3    Rogers, M.4    Kittstein, W.5    Pettit, G.R.6    Herald, C.L.7    Marks, F.8
  • 18
    • 0022578105 scopus 로고
    • Thapsigargin, a histamine secretagogue, is a non-12-o-tetradecanoylphorbol-13-acetate (TPA) type tumor promoter in two-stage mouse skin carcinogenesis
    • Hakii H, Fujiki H, Suganuma M, Nakayusa M, Tahira T, Sugimura T, Scheuer PJ and Christensen SB, Thapsigargin, a histamine secretagogue, is a non-12-O-tetradecanoylphorbol-13-acetate (TPA) type tumor promoter in two-stage mouse skin carcinogenesis. J Cancer Res Clin Oncol III: 177-181, 1986.
    • (1986) J Cancer Res Clin Oncol , vol.3 , pp. 177-181
    • Hakii, H.1    Fujiki, H.2    Suganuma, M.3    Nakayusa, M.4    Tahira, T.5    Sugimura, T.6    Scheuer, P.J.7    Christensen, S.B.8
  • 19
    • 0025733712 scopus 로고
    • Activation of the PKC-isotypes α, βl, γ, δ and ε by phorbol esters of different biological activities
    • Ryves WJ, Evans AT, Olivier AR, Parker PJ and Evans FJ, Activation of the PKC-isotypes α, βl, γ, δ and ε by phorbol esters of different biological activities. FEBS Lett 288: 5-9, 1991.
    • (1991) FEBS Lett , vol.288 , pp. 5-9
    • Ryves, W.J.1    Evans, A.T.2    Olivier, A.R.3    Parker, P.J.4    Evans, F.J.5
  • 20
    • 0027297104 scopus 로고
    • Characterization of ligand and substrate specificity for the calcium-dependent and calcium-independent protein kinase C isozymes
    • Kazanietz MG, Areces LB, Bahador A, Mischak H, Goodnight J, Mushinski JF and Blumberg PM, Characterization of ligand and substrate specificity for the calcium-dependent and calcium-independent protein kinase C isozymes. Mol Pharmacol 44: 298-307, 1993.
    • (1993) Mol Pharmacol , vol.44 , pp. 298-307
    • Kazanietz, M.G.1    Areces, L.B.2    Bahador, A.3    Mischak, H.4    Goodnight, J.5    Mushinski, J.F.6    Blumberg, P.M.7
  • 21
    • 0028144797 scopus 로고
    • Comparison of different tumor promoters and bryostatin 1 on protein kinase C activation and down-regulation in rat renal mesangial cells
    • Huwiler A, Fabbro D and Pfeilschifter J, Comparison of different tumor promoters and bryostatin 1 on protein kinase C activation and down-regulation in rat renal mesangial cells. Biochem Pharmacol 48: 689-700, 1994.
    • (1994) Biochem Pharmacol , vol.48 , pp. 689-700
    • Huwiler, A.1    Fabbro, D.2    Pfeilschifter, J.3
  • 22
    • 0026335593 scopus 로고
    • Expression of protein kinase C isotypes using baculovirus vectors
    • Stabel S, Schaap D and Parker PJ, Expression of protein kinase C isotypes using baculovirus vectors. Methods Enzymol 200: 670-673, 1992.
    • (1992) Methods Enzymol , vol.200 , pp. 670-673
    • Stabel, S.1    Schaap, D.2    Parker, P.J.3
  • 23
    • 0026519632 scopus 로고
    • Protein kinase C group members PKC-δ, -ε, ζ and PKC-L (η): Comparison of properties of recombinant proteins in vitro and in vivo
    • Liyanage M, Frith D, Livneh E and Stabel S, Protein kinase C group members PKC-δ, -ε, ζ and PKC-L (η): Comparison of properties of recombinant proteins in vitro and in vivo. Biochem J 283: 781-787, 1992.
    • (1992) Biochem J , vol.283 , pp. 781-787
    • Liyanage, M.1    Frith, D.2    Livneh, E.3    Stabel, S.4
  • 24
    • 0026696106 scopus 로고
    • Expression and partial characterization of rat protein kinase C-δ and protein kinase C-ζ in insect cells using recombinant baculovirus
    • McGlynn E, Liebetanz J, Reutener S, Wood J, Lydon NB, Hofstetter H, Vanek M, Meyer T and Fabbro D, Expression and partial characterization of rat protein kinase C-δ and protein kinase C-ζ in insect cells using recombinant baculovirus. J Cell Biochem 49: 239-250, 1992.
    • (1992) J Cell Biochem , vol.49 , pp. 239-250
    • McGlynn, E.1    Liebetanz, J.2    Reutener, S.3    Wood, J.4    Lydon, N.B.5    Hofstetter, H.6    Vanek, M.7    Meyer, T.8    Fabbro, D.9
  • 25
    • 0025687388 scopus 로고
    • A phorbol ester receptor/protein kinase, nPKCη, a new member of the protein kinase C family predominantly expressed in lung and skin
    • Osada S-i, Mizuno K, Saido TC, Akita Y, Suzuki K, Kuroki T and Ohno S, A phorbol ester receptor/protein kinase, nPKCη, a new member of the protein kinase C family predominantly expressed in lung and skin. J Biol Chem 265: 22434-22440, 1990.
    • (1990) J Biol Chem , vol.265 , pp. 22434-22440
    • Osada, S.-I.1    Mizuno, K.2    Saido, T.C.3    Akita, Y.4    Suzuki, K.5    Kuroki, T.6    Ohno, S.7
  • 28
    • 0024340030 scopus 로고
    • Biosynthesis and posttranslational modifications of protein kinase C in human breast cancer cells
    • Borner C, Filipuzzi I, Wartmann M, Eppenberger U and Fabbro D, Biosynthesis and posttranslational modifications of protein kinase C in human breast cancer cells. J Biol Chem 264: 13902-13909, 1989.
    • (1989) J Biol Chem , vol.264 , pp. 13902-13909
    • Borner, C.1    Filipuzzi, I.2    Wartmann, M.3    Eppenberger, U.4    Fabbro, D.5
  • 29
    • 0022447890 scopus 로고
    • Epidermal growth factor binding and protein kinase C activities in human breast cancer cell lines: Possible quantitative relationship
    • Fabbro D, Küng W, Roos W, Regazzi R and Eppenberger U, Epidermal growth factor binding and protein kinase C activities in human breast cancer cell lines: Possible quantitative relationship. Cancer Res 46: 2720-2725, 1986.
    • (1986) Cancer Res , vol.46 , pp. 2720-2725
    • Fabbro, D.1    Küng, W.2    Roos, W.3    Regazzi, R.4    Eppenberger, U.5
  • 30
    • 0027978538 scopus 로고
    • Protein kinase C and mammary cell differentiation: Involvement of PKC-α in the induction of β-casein expression
    • Marte BM, Meyer T, Stabel S, Jaken S, Fabbro D and Hynes NE, Protein kinase C and mammary cell differentiation: Involvement of PKC-α in the induction of β-casein expression. Cell Growth Diff 5: 239-247, 1994.
    • (1994) Cell Growth Diff , vol.5 , pp. 239-247
    • Marte, B.M.1    Meyer, T.2    Stabel, S.3    Jaken, S.4    Fabbro, D.5    Hynes, N.E.6
  • 31
    • 0026658539 scopus 로고
    • Purification and characterization of the ζ isoform of protein kinase C from bovine kidney
    • Nakanishi H and Exton JH, Purification and characterization of the ζ isoform of protein kinase C from bovine kidney. J Biol Chem 267: 16347-16354, 1992.
    • (1992) J Biol Chem , vol.267 , pp. 16347-16354
    • Nakanishi, H.1    Exton, J.H.2
  • 33
    • 0025648519 scopus 로고
    • Effector-dependent conformational changes in protein kinase Cγ through epitope mapping with inhibitory monoclonal antibodies
    • Cazaubon S, Webster C, Camoin L, Strosberg AD and Parker PJ, Effector-dependent conformational changes in protein kinase Cγ through epitope mapping with inhibitory monoclonal antibodies. Eur J Biochem 194: 799-804, 1990.
    • (1990) Eur J Biochem , vol.194 , pp. 799-804
    • Cazaubon, S.1    Webster, C.2    Camoin, L.3    Strosberg, A.D.4    Parker, P.J.5
  • 34
    • 0026062945 scopus 로고
    • Protein kinase C contains two phorbol ester binding domains
    • Burns DJ and Bell RM, Protein kinase C contains two phorbol ester binding domains. J Biol Chem 266: 18330-18338, 1991.
    • (1991) J Biol Chem , vol.266 , pp. 18330-18338
    • Burns, D.J.1    Bell, R.M.2
  • 35
    • 0025317705 scopus 로고
    • Expression, purification, and characterization of protein kinase C-ε
    • Schaap D and Parker PJ, Expression, purification, and characterization of protein kinase C-ε. J Biol Chem 265: 7301-7307, 1990.
    • (1990) J Biol Chem , vol.265 , pp. 7301-7307
    • Schaap, D.1    Parker, P.J.2
  • 36
    • 0026507722 scopus 로고
    • Immuno-characterization of δ-and ζ-isoenzymes of protein kinase C in rat renal mesangial cells
    • Huwiler A, Fabbro D, Stabel S and Pfeilschifter J, Immuno-characterization of δ-and ζ-isoenzymes of protein kinase C in rat renal mesangial cells. FEES Lett 300: 259-262, 1992.
    • (1992) FEES Lett , vol.300 , pp. 259-262
    • Huwiler, A.1    Fabbro, D.2    Stabel, S.3    Pfeilschifter, J.4
  • 38
    • 0024379951 scopus 로고
    • A derivative of Staurosporine (CGP 41251) shows selectivity for protein kinase C inhibition and in vitro anti-proliferative as well as in vivo anti-tumor activity
    • Meyer T, Regenass U, Fabbro D, Alteri E, Rösel J, Müller M, Caravatti G and Matter A, A derivative of Staurosporine (CGP 41251) shows selectivity for protein kinase C inhibition and in vitro anti-proliferative as well as in vivo anti-tumor activity. Int J Cancer 43: 851-856, 1989.
    • (1989) Int J Cancer , vol.43 , pp. 851-856
    • Meyer, T.1    Regenass, U.2    Fabbro, D.3    Alteri, E.4    Rösel, J.5    Müller, M.6    Caravatti, G.7    Matter, A.8
  • 39
    • 0022500301 scopus 로고
    • K252a, a potent inhibitor of protein kinase C from microbial origin
    • Kase H, Iwahashi K and Matsuda Y, K252a, a potent inhibitor of protein kinase C from microbial origin. J Antibiot 39: 1059-1063, 1986.
    • (1986) J Antibiot , vol.39 , pp. 1059-1063
    • Kase, H.1    Iwahashi, K.2    Matsuda, Y.3
  • 41
    • 0026067787 scopus 로고
    • 11protein kinase C to the nucleus of human promyelocytic (HL60) leukemia cells
    • 11protein kinase C to the nucleus of human promyelocytic (HL60) leukemia cells. J Biol Chem 266: 28-33, 1991.
    • (1991) J Biol Chem , vol.266 , pp. 28-33
    • Hocevar, B.A.1    Fields, A.P.2
  • 42
    • 0028055160 scopus 로고
    • Differen-tial regulation of protein kinase C isozymes by bryostatin 1 and phorbol 12-myristate 13-acetate in NIH 3T3 fibroblasts
    • Szallasi Z, Smith CB, Pettit GR and Blumberg PM, Differen-tial regulation of protein kinase C isozymes by bryostatin 1 and phorbol 12-myristate 13-acetate in NIH 3T3 fibroblasts. J Biol Chem 269: 2118-2124, 1994.
    • (1994) J Biol Chem , vol.269 , pp. 2118-2124
    • Szallasi, Z.1    Smith, C.B.2    Pettit, G.R.3    Blumberg, P.M.4
  • 43
    • 0026779291 scopus 로고
    • Differential irreversible insertion of protein kinase C into phospholipid vesicles by phorbol esters and related activators
    • Kazanietz MG, Krausz KW and Blumberg PM, Differential irreversible insertion of protein kinase C into phospholipid vesicles by phorbol esters and related activators. J Biol Chem 267: 20878-20886, 1992.
    • (1992) J Biol Chem , vol.267 , pp. 20878-20886
    • Kazanietz, M.G.1    Krausz, K.W.2    Blumberg, P.M.3
  • 45
    • 0026448386 scopus 로고
    • Selective redistribution of protein kinase C isozymes by thapsigargin and staurosporine
    • Kiley SC, Parker PJ, Fabbro D and Jaken S, Selective redistribution of protein kinase C isozymes by thapsigargin and staurosporine. Carcinogenesis 13: 1997-2001, 1992.
    • (1992) Carcinogenesis , vol.13 , pp. 1997-2001
    • Kiley, S.C.1    Parker, P.J.2    Fabbro, D.3    Jaken, S.4
  • 46
    • 0027312987 scopus 로고
    • Staurosporine-related compounds, K252a and UCN-01, inhibit both cPKC and nPKC
    • Mizuno K, Saido TC, Ohno S, Tamaoki T and Suzuki K, Staurosporine-related compounds, K252a and UCN-01, inhibit both cPKC and nPKC. FEES Lett 330: 114-116, 1993.
    • (1993) FEES Lett , vol.330 , pp. 114-116
    • Mizuno, K.1    Saido, T.C.2    Ohno, S.3    Tamaoki, T.4    Suzuki, K.5
  • 47
    • 0027438086 scopus 로고
    • A role for protein kinase-ε in angiotensin II stimulation of phospholipase D in rat renal mesangial cells
    • Pfeilschifter J and Huwiler A, A role for protein kinase-ε in angiotensin II stimulation of phospholipase D in rat renal mesangial cells. FEBS Lett 331: 267-271, 1993.
    • (1993) FEBS Lett , vol.331 , pp. 267-271
    • Pfeilschifter, J.1    Huwiler, A.2
  • 48
    • 0027971994 scopus 로고
    • Stimulation by extracellular ATP and UTP of the mitogen-activated protein kinase cas-cade and proliferation of rat renal mesangial cells
    • Huwiler A and Pfeilschifter J, Stimulation by extracellular ATP and UTP of the mitogen-activated protein kinase cas-cade and proliferation of rat renal mesangial cells. Br J Pharmacol 113: 1455-1463, 1994.
    • (1994) Br J Pharmacol , vol.113 , pp. 1455-1463
    • Huwiler, A.1    Pfeilschifter, J.2
  • 49
    • 0027943828 scopus 로고
    • Possible role of protein kinase C-ε. Isoenzyme in inhibition of interleukin 1β induction of nitric oxide synthase in rat renal mesangial cells
    • Mühl H and Pfeilschifter J, Possible role of protein kinase C-ε. isoenzyme in inhibition of interleukin 1β induction of nitric oxide synthase in rat renal mesangial cells. Biochem J 303: 607-612, 1994.
    • (1994) Biochem J , vol.303 , pp. 607-612
    • Mühl, H.1    Pfeilschifter, J.2
  • 50
    • 0027448972 scopus 로고
    • A role for protein kinase C-α in zymosan-stimulated eicosanoid synthesis in mouse peritoneal macrophages
    • Huwiler A and Pfeilschifter J, A role for protein kinase C-α in zymosan-stimulated eicosanoid synthesis in mouse peritoneal macrophages. Eur J Biochem 217: 69-75, 1993.
    • (1993) Eur J Biochem , vol.217 , pp. 69-75
    • Huwiler, A.1    Pfeilschifter, J.2


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