Downregulation of free ubiquitin: A novel mechanism of p53 stabilization and neuronal cell death

Molecular Brain Research

Volumn 91, Issue 1-2, 2001, Pages 179-188

  Tan, Zhiqun ^a   Tu, Wenli ^a   Schreiber, Steven S ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Mdm2; Neuronal cell death; p53; Protein degradation; Ubiquitin

Indexed keywords

CAMPTOTHECIN; DNA TOPOISOMERASE INHIBITOR; EXCITOTOXIN; KAINIC ACID; PROTEIN MDM2; PROTEIN P53; UBIQUITIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CELL DEGENERATION; CELL LYSATE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DEGENERATIVE DISEASE; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOPRECIPITATION; MALE; NERVE CELL; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN STABILITY; PROTEIN TARGETING; RAT; REGULATORY MECHANISM; STRESS; TREATMENT OUTCOME;

ANIMALS; BRAIN; CAMPTOTHECIN; CELL DEATH; CELLS, CULTURED; DNA DAMAGE; DOWN-REGULATION; ENZYME INHIBITORS; EXCITATORY AMINO ACID AGONISTS; IN SITU NICK-END LABELING; KAINIC ACID; MALE; NERVE DEGENERATION; NEURONS; NUCLEAR PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MDM2; RATS; RATS, SPRAGUE-DAWLEY; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITINS;

EID: 0035854477     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(01)00117-6     Document Type: Article

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